Washington State University

About: Washington State University is a education organization based out in Pullman, Washington, United States. It is known for research contribution in the topics: Population & Gene. The organization has 26947 authors who have published 57736 publications receiving 2341509 citations. The organization is also known as: WSU & Wazzu.

Shortest-path algorithms: Taxonomy and annotation

Abstract: We have evolved a classification scheme to characterize algorithms for solving shortestpath problems. The algorithms are classified according to (A) the problem type, i.e., the question being asked about the given network; (B) the input type, i.e., the salient features of the given network which impact on the design of the algorithm and selection of data structures; and (C) the type of underlying technique employed to solve the problem. An annotated bibliography of 79 selected references on shortest-path algorithms is included. We have also provided a more complete listing of 222 references carefully culled out of a larger body of literature on shortest-path algorithms through the year 1979.

The Ethical Climate Questionnaire: An Assessment of its Development and Validity:

Abstract: The Ethical Climate Questionnaire measures the ethical climates at individual and organizational levels of analysis. With 1,167 individuals tested across three surveys the results at the individual level have suggested strong support for the validity and reliability of the questionnaire However, given the limited number of organizations (n = 12) surveyed, the presence of organizational-level ethical climates remains contestable. This paper reports on the development of the Ethical Climate Questionnaire, includes the results of the latest survey, and contrasts these results with previous findings.

A ubiquitous tire rubber–derived chemical induces acute mortality in coho salmon

Abstract: In U.S. Pacific Northwest coho salmon (Oncorhynchus kisutch), stormwater exposure annually causes unexplained acute mortality when adult salmon migrate to urban creeks to reproduce. By investigating this phenomenon, we identified a highly toxic quinone transformation product of N-(1,3-dimethylbutyl)-N9-phenyl-p-phenylenediamine) (6PPD), a globally ubiquitous tire rubber antioxidant. Retrospective analysis of representative roadway runoff and stormwater-impacted creeks of the U.S. West Coast indicated widespread occurrence of 6PPD-quinone (

Identification and Characterization of a Gene Cluster for Synthesis of the Polyketide Antibiotic 2,4-Diacetylphloroglucinol from Pseudomonas fluorescens Q2-87

Abstract: The polyketide metabolite 2,4-diacetylphloroglucinol (2,4-DAPG) is produced by many strains of fluorescent Pseudomonas spp. with biocontrol activity against soilborne fungal plant pathogens. Genes required for 2,4-DAPG synthesis by P. fluorescens Q2-87 are encoded by a 6.5-kb fragment of genomic DNA that can transfer production of 2,4-DAPG to 2,4-DAPG-nonproducing recipient Pseudomonas strains. In this study the nucleotide sequence was determined for the 6.5-kb fragment and flanking regions of genomic DNA from strain Q2-87. Six open reading frames were identified, four of which (phlACBD) comprise an operon that includes a set of three genes (phlACB) conserved between eubacteria and archaebacteria and a gene (phlD) encoding a polyketide synthase with homology to chalcone and stilbene synthases from plants. The biosynthetic operon is flanked on either side by phlE and phlF, which code respectively for putative efflux and regulatory (repressor) proteins. Expression in Escherichia coli of phlA, phlC, phlB, and phlD, individually or in combination, identified a novel polyketide biosynthetic pathway in which PhlD is responsible for the production of monoacetylphloroglucinol (MAPG). PhlA, PhlC, and PhlB are necessary to convert MAPG to 2,4-DAPG, and they also may function in the synthesis of MAPG.