Institution
Washington State University
Education•Pullman, Washington, United States•
About: Washington State University is a education organization based out in Pullman, Washington, United States. It is known for research contribution in the topics: Population & Gene. The organization has 26947 authors who have published 57736 publications receiving 2341509 citations. The organization is also known as: WSU & Wazzu.
Topics: Population, Gene, Poison control, Catalysis, Hordeum vulgare
Papers published on a yearly basis
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TL;DR: It is proposed that reactive Cys persulfides and S-polythiolation have critical regulatory functions in redox cell signaling and H2S may act primarily as a marker for the biologically active of persulfide species.
Abstract: Using methodology developed herein, it is found that reactive persulfides and polysulfides are formed endogenously from both small molecule species and proteins in high amounts in mammalian cells and tissues. These reactive sulfur species were biosynthesized by two major sulfurtransferases: cystathionine β-synthase and cystathionine γ-lyase. Quantitation of these species indicates that high concentrations of glutathione persulfide (perhydropersulfide >100 μM) and other cysteine persulfide and polysulfide derivatives in peptides/proteins were endogenously produced and maintained in the plasma, cells, and tissues of mammals (rodent and human). It is expected that persulfides are especially nucleophilic and reducing. This view was found to be the case, because they quickly react with H2O2 and a recently described biologically generated electrophile 8-nitroguanosine 3′,5′-cyclic monophosphate. These results indicate that persulfides are potentially important signaling/effector species, and because H2S can be generated from persulfide degradation, much of the reported biological activity associated with H2S may actually be that of persulfides. That is, H2S may act primarily as a marker for the biologically active of persulfide species.
688 citations
TL;DR: In Taiwan, tourism and economic development reinforce each other, indicating a long-run equilibrium relationship and further a bi-directional causality between the two factors.
686 citations
TL;DR: Although institutional investors have a preference for large capitalization stocks, over time they have shifted their preferences toward smaller, riskier securities as mentioned in this paper, and evidence also suggests that recent growth in institutional investment combined with this shift in preferences helps explain why markets in general and smaller stocks in particular, have exhibited greater firm-specific risk and liquidity.
Abstract: Although institutional investors have a preference for large capitalization stocks, over time they have shifted their preferences toward smaller, riskier securities. These changes in aggregate preferences have arisen primarily from changes in the preferences of each class of institution, rather than changes in the importance of different classes. Evidence also suggests that recent growth in institutional investment combined with this shift in preferences helps explain why markets in general, and smaller stocks in particular, have exhibited greater firm-specific risk and liquidity in recent years. Additional analyses suggest that institutional investors moved toward smaller securities because such securities offer "greener pastures." Copyright 2003, Oxford University Press.
685 citations
University of Glasgow1, University of Salerno2, Max Planck Society3, University of Southampton4, University of Paris-Sud5, University of Nice Sophia Antipolis6, Washington State University7, Istituto Nazionale di Fisica Nucleare8, University of Warsaw9, University of Naples Federico II10, University of Birmingham11, Cardiff University12, University of Rome Tor Vergata13, Moscow State University14, California Institute of Technology15, VU University Amsterdam16, fondazione bruno kessler17, Leibniz University of Hanover18, University of Cambridge19, University of Tübingen20, University of Urbino21, University of Jena22, University of the Balearic Islands23, Northwestern University24, University of Minnesota25, University of Savoy26, Pennsylvania State University27, University of Pisa28, Roma Tre University29, Sapienza University of Rome30, University of Mississippi31
TL;DR: In this article, a special focus is set on evaluating the frequency band below 10 Hz where a complex mixture of seismic, gravity gradient, suspension thermal and radiation pressure noise dominates, including the most relevant fundamental noise contributions.
Abstract: Advanced gravitational wave detectors, currently under construction, are expected to directly observe gravitational wave signals of astrophysical origin. The Einstein Telescope (ET), a third-generation gravitational wave detector, has been proposed in order to fully open up the emerging field of gravitational wave astronomy. In this paper we describe sensitivity models for ET and investigate potential limits imposed by fundamental noise sources. A special focus is set on evaluating the frequency band below 10 Hz where a complex mixture of seismic, gravity gradient, suspension thermal and radiation pressure noise dominates. We develop the most accurate sensitivity model, referred to as ET-D, for a third-generation detector so far, including the most relevant fundamental noise contributions.
682 citations
University of Missouri1, Auburn University2, University of Cincinnati3, United States Environmental Protection Agency4, Maryville College5, University of Siena6, University of Florida7, Harvard University8, National Institutes of Health9, Washington State University10, National Institutes of Natural Sciences, Japan11, Brunel University London12, Case Western Reserve University13, University of Connecticut14, North Carolina State University15, Emory University16, Tulane University17, Universidad Miguel Hernández de Elche18, University of Granada19, University of Illinois at Chicago20, United States Geological Survey21, Tufts University22, Charité23, Carleton College24, University of Texas Medical Branch25, University of Massachusetts Amherst26
TL;DR: This document is a summary statement of the outcome from he meeting: “Bisphenol A: An Examination of the Relevance of cological, In vitro and Laboratory Animal Studies for Assessng Risks to Human Health” sponsored by both the NIEHS and IDCR at NIH/DHHS.
681 citations
Authors
Showing all 27183 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Anil K. Jain | 183 | 1016 | 192151 |
| Martin Karplus | 163 | 831 | 138492 |
| Herbert A. Simon | 157 | 745 | 194597 |
| Suvadeep Bose | 154 | 960 | 129071 |
| Rajesh Kumar | 149 | 4439 | 140830 |
| Kevin Murphy | 146 | 728 | 120475 |
| Jonathan D. G. Jones | 129 | 417 | 80908 |
| Douglas E. Soltis | 127 | 612 | 67161 |
| Peter W. Kalivas | 123 | 428 | 52445 |
| Chris Somerville | 122 | 284 | 45742 |
| Pamela S. Soltis | 120 | 543 | 61080 |
| Yuehe Lin | 118 | 641 | 55399 |
| Howard I. Maibach | 116 | 1821 | 60765 |
| Jizhong Zhou | 115 | 766 | 48708 |
| Farshid Guilak | 110 | 480 | 41327 |