Wichita State University

About: Wichita State University is a education organization based out in Wichita, Kansas, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 4988 authors who have published 9563 publications receiving 253824 citations. The organization is also known as: WSU & Fairmount College.

Structure-based design of a general class of mechanism-based inhibitors of the serine proteinases employing a novel amino acid-derived heterocyclic scaffold.

Abstract: We describe in this paper the structure-based design of a general class of heterocyclic mechanism-based inhibitors of the serine proteinases that embody in their structure a novel peptidomimetic sc...

Automated detection and classification of vascular abnormalities in diabetic retinopathy

Abstract: Diabetic retinopathy is a progressive ocular disease. The disease may advance from mild to severe non-proliferative diabetic retinopathy. This paper proposes a method for automated detection and classification of vascular abnormalities in diabetic retinopathy. The vascular abnormalities are detected using scale and orientation selective Gabor filter banks. The proposed method classifies the retinal image as mild or severe case based on the outputs obtained from Gabor filters.

Automatic Landing System Design Using Fuzzy Logic

Abstract: A fuzzy logic system is developed for automatic landing control of a transport aircraft. A linear longitudinal aircraft model, with landing gear and flaps deployed at the sea level, is employed for fuzzy logic controller design of automatic landing system including the two landing phases - the glide-path capture and the flare maneuver. In addition, the fuzzy control system is tested using different values of fuzzy controller scaling factors on a six degree of. freedom nonlinear aircraft model. It is shown that the simple tuning fuzzy controller with altered scaling factors is well suited for controlling the trajectory of the aircraft in the landing phase which requires simultaneous control of engine thrust for the velocity and elevator for the pitch attitude in order to change altitude with a constant airspeed.

On the Primordial Scenario for Abundance Variations within Globular Clusters: The Isochrone Test

Abstract: Self-enrichment processes occurring in the early stages of a globular cluster lifetime are generally invoked to explain the observed CNONaMgAl abundance anticorrelations within individual Galactic globular clusters. We have tested, with fully consistent stellar evolution calculations, whether theoretical isochrones for stars born with the observed abundance anticorrelations satisfy the observational evidence that objects with different degrees of these anomalies lie on essentially identical sequences in the color-magnitude diagram (CMD). To this purpose, we have computed for the first time low-mass stellar models and isochrones with an initial metal mixture that includes the extreme values of the observed abundance anticorrelations and varying initial He mass fractions. Comparisons with "normal" α-enhanced isochrones and suitable Monte Carlo simulations that include photometric errors show that a significant broadening of the CMD sequences occurs only if the helium enhancement is extremely large (in this study, when Y = 0.35) in the stars showing anomalous abundances. Stellar luminosity functions up to the red giant branch tip are also very weakly affected, apart from—depending on the He content of the polluting material—the red giant branch bump region. We also study the distribution of stars along the zero-age horizontal branch and derive general constraints on the relative location of objects with and without abundance anomalies along the observed horizontal branches of globular clusters.