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World Health Organization

GovernmentIslamabad, Pakistan
About: World Health Organization is a government organization based out in Islamabad, Pakistan. It is known for research contribution in the topics: Population & Public health. The organization has 13330 authors who have published 22232 publications receiving 1322023 citations. The organization is also known as: World Health Organisation & WHO.


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Journal ArticleDOI
TL;DR: To assess the impact of inadequate water and sanitation on diarrhoeal disease in low‐ and middle‐income settings, a large number of patients in low- and middle-income settings are exposed to faeces-based infectious diseases.
Abstract: Objective: To assess the impact of inadequate water and sanitation on diarrhoeal disease in low- and middle-income settings. Methods: The search strategy used Cochrane Library, MEDLINE & PubMed, Global Health, Embase and BIOSIS supplemented by screening of reference lists from previously published systematic reviews, to identify studies reporting on interventions examining the effect of drinking water and sanitation improvements in low- and middle-income settings published between 1970 and May 2013. Studies including randomised controlled trials, quasi-randomised trials with control group, observational studies using matching techniques and observational studies with a control group where the intervention was well defined were eligible. Risk of bias was assessed using a modified Ottawa-Newcastle scale. Study results were combined using meta-analysis and meta-regression to derive overall and intervention-specific risk estimates. Results: Of 6819 records identified for drinking water, 61 studies met the inclusion criteria, and of 12 515 records identified for sanitation, 11 studies were included. Overall, improvements in drinking water and sanitation were associated with decreased risks of diarrhoea. Specific improvements, such as the use of water filters, provision of high-quality piped water and sewer connections, were associated with greater reductions in diarrhoea compared with other interventions. Conclusions: The results show that inadequate water and sanitation are associated with considerable risks of diarrhoeal disease and that there are notable differences in illness reduction according to the type of improved water and sanitation implemented.

405 citations

Journal ArticleDOI
Nafees Ahmad, Shama D. Ahuja1, Onno W. Akkerman2, Jan-Willem C. Alffenaar2, Laura F Anderson3, Parvaneh Baghaei4, Didi Bang5, Pennan M. Barry6, Mayara Lisboa Bastos7, Digamber Behera8, Andrea Benedetti9, Gregory P. Bisson10, Martin J. Boeree11, Maryline Bonnet12, Sarah K. Brode13, James C.M. Brust14, Ying Cai15, Eric Caumes, J. Peter Cegielski16, Rosella Centis3, Pei-Chun Chan16, Edward D. Chan17, Kwok-Chiu Chang18, Macarthur Charles16, Andra Cirule, Margareth Pretti Dalcolmo19, Lia D'Ambrosio3, Gerard de Vries, Keertan Dheda20, Aliasgar Esmail20, Jennifer Flood6, Gregory J. Fox21, Mathilde Fréchet-Jachym, Geisa Fregona, Regina Gayoso19, Medea Gegia3, Maria Tarcela Gler, Sue Gu17, Lorenzo Guglielmetti22, Timothy H. Holtz16, Jennifer Hughes23, Petros Isaakidis23, Leah G. Jarlsberg24, Russell R. Kempker25, Salmaan Keshavjee26, Faiz Ahmad Khan9, Maia Kipiani, Serena P. Koenig26, Won-Jung Koh27, Afranio Lineu Kritski28, Liga Kuksa, Charlotte Kvasnovsky29, Nakwon Kwak30, Zhiyi Lan9, Christoph Lange31, Rafael Laniado-Laborín, Myungsun Lee, Vaira Leimane, Chi-Chiu Leung18, Eric Chung Ching Leung18, Pei Zhi Li9, Phil Lowenthal6, Ethel Leonor Noia Maciel, Suzanne M. Marks16, Sundari Mase16, Lawrence Mbuagbaw32, Giovanni Battista Migliori3, Vladimir Milanov33, Ann C. Miller34, Carole D. Mitnick34, Chawangwa Modongo10, Erika Mohr23, Ignacio Monedero, Payam Nahid24, Norbert Ndjeka, Max R. O'Donnell35, Nesri Padayatchi, Domingo Palmero, Jean W. Pape36, Laura Jean Podewils16, Ian R Reynolds17, Vija Riekstina, Jérôme Robert22, Maria I. Rodriguez, Barbara Seaworth37, Kwonjune J. Seung38, Kathryn Schnippel20, Tae Sun Shim39, Rupak Singla, Sarah Smith16, Giovanni Sotgiu40, Ganzaya Sukhbaatar, Payam Tabarsi4, Simon Tiberi41, Anete Trajman28, Lisa Trieu1, Zarir F Udwadia, Tjip S. van der Werf2, Nicolas Veziris22, Piret Viiklepp15, Stalz Charles Vilbrun, Kathleen F. Walsh, Janice Westenhouse6, Wing Wai Yew42, Jae-Joon Yim30, Nicola M. Zetola10, Matteo Zignol3, Dick Menzies9 
TL;DR: Treatment outcomes were significantly better with use of linezolid, later generation fluoroquinolones, bedaquiline, clofazimine, and carbapenems for treatment of multidrug-resistant tuberculosis, and the need for trials to ascertain the optimal combination and duration of these drugs is emphasised.

404 citations

Journal ArticleDOI
Claudio L. Afonso1, Gaya K. Amarasinghe2, Krisztián Bányai3, Yīmíng Bào4, Christopher F. Basler5, Sina Bavari6, Nicolás Bejerman, Kim R. Blasdell7, François Xavier Briand, Thomas Briese8, Alexander Bukreyev9, Charles H. Calisher10, Kartik Chandran11, Jiāsēn Chéng12, Anna N. Clawson4, Peter L. Collins4, Ralf G. Dietzgen13, Olga Dolnik14, Leslie L. Domier15, Ralf Dürrwald, John M. Dye6, Andrew J. Easton16, Hideki Ebihara4, Szilvia L. Farkas3, Juliana Freitas-Astúa17, Pierre Formenty18, Ron A. M. Fouchier19, Yanping Fu12, Elodie Ghedin20, Michael M. Goodin21, Roger Hewson22, Masayuki Horie23, Timothy H. Hyndman24, Dàohóng Jiāng12, E. W. Kitajima25, Gary P. Kobinger26, Hideki Kondo27, Gael Kurath28, Robert A. Lamb29, Sergio Lenardon, Eric M. Leroy, C. Li, Xian Dan Lin30, Lìjiāng Liú12, Ben Longdon31, Szilvia Marton3, Andrea Maisner14, Elke Mühlberger32, Sergey V. Netesov33, Norbert Nowotny34, Norbert Nowotny35, Jean L. Patterson36, Susan Payne37, Janusz T. Paweska, Richard E. Randall38, Bertus K. Rima39, Paul A. Rota30, Dennis Rubbenstroth40, Martin Schwemmle40, Mang Shi41, Sophie J. Smither42, Mark D. Stenglein10, David M. Stone, Ayato Takada43, Calogero Terregino, Robert B. Tesh9, Jun Hua Tian30, Keizo Tomonaga44, Noël Tordo45, Jonathan S. Towner30, Nikos Vasilakis9, Martin Verbeek46, Viktor E. Volchkov47, Victoria Wahl-Jensen, John A. Walsh16, Peter J. Walker7, David Wang2, Lin-Fa Wang48, Thierry Wetzel, Anna E. Whitfield49, Jiǎtāo Xiè12, Kwok-Yung Yuen50, Yong-Zhen Zhang41, Jens H. Kuhn4 
United States Department of Agriculture1, Washington University in St. Louis2, Hungarian Academy of Sciences3, National Institutes of Health4, Georgia State University5, United States Army Medical Research Institute of Infectious Diseases6, Commonwealth Scientific and Industrial Research Organisation7, Columbia University8, University of Texas Medical Branch9, Colorado State University10, Yeshiva University11, Huazhong Agricultural University12, University of Queensland13, University of Marburg14, University of Illinois at Urbana–Champaign15, University of Warwick16, Empresa Brasileira de Pesquisa Agropecuária17, World Health Organization18, Erasmus University Rotterdam19, New York University20, University of Kentucky21, Public Health England22, Kagoshima University23, Murdoch University24, University of São Paulo25, Public Health Agency of Canada26, Okayama University27, United States Geological Survey28, Northwestern University29, Centers for Disease Control and Prevention30, University of Cambridge31, Boston University32, Novosibirsk State University33, University of Medicine and Health Sciences34, University of Veterinary Medicine Vienna35, Texas Biomedical Research Institute36, Texas A&M University37, University of St Andrews38, Queen's University Belfast39, University of Freiburg40, Chinese Center for Disease Control and Prevention41, Defence Science and Technology Laboratory42, Hokkaido University43, Kyoto University44, Pasteur Institute45, Wageningen University and Research Centre46, University of Lyon47, National University of Singapore48, Kansas State University49, University of Hong Kong50
TL;DR: The updated taxonomy of the order Mononegavirales is presented as now accepted by the International Committee on Taxonomy of Viruses (ICTV).
Abstract: In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae), the addition of five free-floating genera (Anphevirus, Arlivirus, Chengtivirus, Crustavirus, and Wastrivirus), and several other changes at the genus and species levels. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV).

404 citations

Journal ArticleDOI
08 Feb 2008-Science
TL;DR: It is suggested that the main obstacles to improving urban health are not technical or even financial, but rather are related to governance and the organization of civil society.
Abstract: The majority of people now live in urban areas and will do so for the foreseeable future. As a force in the demographic and health transition, urbanization is associated with falling birth and death rates and with the shift in burden of illness from acute childhood infections to chronic, noncommunicable diseases of adults. Urban inhabitants enjoy better health on average than their rural counterparts, but the benefits are usually greater for the rich than for the poor, thus magnifying the differences between them. Subject to better evidence, I suggest that the main obstacles to improving urban health are not technical or even financial, but rather are related to governance and the organization of civil society.

403 citations

Journal ArticleDOI
TL;DR: The findings support the recommendation of the Global Commission for the Certification of Smallpox Eradication to cease routine smallpox vaccination in monkeypox endemic areas, but to encourage continued epidemiological surveillance.
Abstract: Data on monkeypox in Zaire over the five years 1980-1984 are analysed to assess the protection imparted by past smallpox vaccination and the transmission potential of the virus in unvaccinated communities. Attack rates in individuals with and without vaccination scars indicated that smallpox vaccination (discontinued in 1980) imparted approximately 85% protection against monkeypox. It is predicted that monkeypox virus will continue to be introduced into human communities from animal sources, and that the average magnitude and duration of monkeypox epidemics will increase as vaccine-derived protection declines in the population. On the other hand, current evidence indicates that the virus is appreciably less transmissible than was smallpox, and that it will not persist in human communities, even in the total absence of vaccination. The findings thus support the recommendation of the Global Commission for the Certification of Smallpox Eradication to cease routine smallpox vaccination in monkeypox endemic areas, but to encourage continued epidemiological surveillance.

402 citations


Authors

Showing all 13385 results

NameH-indexPapersCitations
Christopher J L Murray209754310329
Michael Marmot1931147170338
Didier Raoult1733267153016
Alan D. Lopez172863259291
Zulfiqar A Bhutta1651231169329
Simon I. Hay165557153307
Robert G. Webster15884390776
Ali H. Mokdad156634160599
Matthias Egger152901184176
Paolo Boffetta148145593876
Jean Bousquet145128896769
Igor Rudan142658103659
Holger J. Schünemann141810113169
Richard M. Myers134496137791
Majid Ezzati133443137171
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202319
202279
20211,792
20201,612
20191,402
20181,360