Institution
World Health Organization
Government•Islamabad, Pakistan•
About: World Health Organization is a government organization based out in Islamabad, Pakistan. It is known for research contribution in the topics: Population & Public health. The organization has 13330 authors who have published 22232 publications receiving 1322023 citations. The organization is also known as: World Health Organisation & WHO.
Topics: Population, Public health, Health care, Health policy, Global health
Papers published on a yearly basis
Papers
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TL;DR: In this report, orally administered drugs on the Model list of Essential Medicines of the World Health Organization (WHO) are assigned BCS classifications on the basis of data available in the public domain.
788 citations
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New York University1, J. Craig Venter Institute2, University of South Florida3, University of Maryland, Baltimore4, University of Maryland, College Park5, World Health Organization6, Burnet Institute7, University of Pennsylvania8, University of Barcelona9, Walter and Eliza Hall Institute of Medical Research10, Hood College11, Heidelberg University12, University of Queensland13, Emory University14, Macquarie University15, University of Melbourne16, University of São Paulo17, Centers for Disease Control and Prevention18
TL;DR: The synteny and isochore structure of P. vivax chromosomes are described, and it is shown that the parasite resembles other malaria parasites in gene content and metabolic potential, but possesses novel gene families and potential alternative invasion pathways not recognized previously.
Abstract: The human malaria parasite Plasmodium vivax is responsible for 25-40% of the approximately 515 million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe and incapacitating clinical symptoms and often causes relapses months after a primary infection has cleared. Despite its importance as a major human pathogen, P. vivax is little studied because it cannot be propagated continuously in the laboratory except in non-human primates. We sequenced the genome of P. vivax to shed light on its distinctive biological features, and as a means to drive development of new drugs and vaccines. Here we describe the synteny and isochore structure of P. vivax chromosomes, and show that the parasite resembles other malaria parasites in gene content and metabolic potential, but possesses novel gene families and potential alternative invasion pathways not recognized previously. Completion of the P. vivax genome provides the scientific community with a valuable resource that can be used to advance investigation into this neglected species.
787 citations
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TL;DR: It is recommended that policymakers should act on the available evidence to scale up effective and cost-effective treatments and preventive interventions for mental disorders and community-based rehabilitation models provide a low-cost, integrative framework for care of children and adults with chronic mental disabilities.
787 citations
01 Jan 2003
TL;DR: The growing scale, variety and frequency of major emergencies, the HIV/AIDS pandemic, complexities of modern lifestyles, coupled with continued promulgation of mixed messages and changing fashion with regard to breastfeeding complicate meeting the nutritional needs of infants and young children.
Abstract: 1. Some 1.5 million children still die every year because they are inappropriately fed, less than 35% of infants worldwide are exclusively breastfed for the first four months of life, and complementary feeding practices are frequently inappropriate and unsafe. The growing scale, variety and frequency of major emergencies, the HIV/AIDS pandemic, complexities of modern lifestyles, coupled with continued promulgation of mixed messages and changing fashion with regard to breastfeeding complicate meeting the nutritional needs of infants and young children.
783 citations
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TL;DR: The conceptual and methodological issues for quantifying the population health effects of individual or groups of risk factors in various levels of causality using knowledge from different scientific disciplines are discussed.
Abstract: Reliable and comparable analysis of risks to health is key for preventing disease and injury. Causal attribution of morbidity and mortality to risk factors has traditionally been conducted in the context of methodological traditions of individual risk factors, often in a limited number of settings, restricting comparability.In this paper, we discuss the conceptual and methodological issues for quantifying the population health effects of individual or groups of risk factors in various levels of causality using knowledge from different scientific disciplines. The issues include: comparing the burden of disease due to the observed exposure distribution in a population with the burden from a hypothetical distribution or series of distributions, rather than a single reference level such as non-exposed; considering the multiple stages in the causal network of interactions among risk factor(s) and disease outcome to allow making inferences about some combinations of risk factors for which epidemiological studies have not been conducted, including the joint effects of multiple risk factors; calculating the health loss due to risk factor(s) as a time-indexed "stream" of disease burden due to a time-indexed "stream" of exposure, including consideration of discounting; and the sources of uncertainty.
778 citations
Authors
Showing all 13385 results
Name | H-index | Papers | Citations |
---|---|---|---|
Christopher J L Murray | 209 | 754 | 310329 |
Michael Marmot | 193 | 1147 | 170338 |
Didier Raoult | 173 | 3267 | 153016 |
Alan D. Lopez | 172 | 863 | 259291 |
Zulfiqar A Bhutta | 165 | 1231 | 169329 |
Simon I. Hay | 165 | 557 | 153307 |
Robert G. Webster | 158 | 843 | 90776 |
Ali H. Mokdad | 156 | 634 | 160599 |
Matthias Egger | 152 | 901 | 184176 |
Paolo Boffetta | 148 | 1455 | 93876 |
Jean Bousquet | 145 | 1288 | 96769 |
Igor Rudan | 142 | 658 | 103659 |
Holger J. Schünemann | 141 | 810 | 113169 |
Richard M. Myers | 134 | 496 | 137791 |
Majid Ezzati | 133 | 443 | 137171 |