World Health Organization

About: World Health Organization is a government organization based out in Islamabad, Pakistan. It is known for research contribution in the topics: Population & Public health. The organization has 13330 authors who have published 22232 publications receiving 1322023 citations. The organization is also known as: World Health Organisation & WHO.

Integrated management of childhood illness by outpatient health workers: technical basis and overview. The WHO Working Group on Guidelines for Integrated Management of the Sick Child.

Abstract: About 12 million children under age 5 years die annually in developing countries 70% of which are due to pneumonia diarrhea malaria measles and malnutrition and 75% of children who seek health care at health facilities do so in response to morbidity from one of these conditions. Potentially fatal illnesses are often brought to the attention of health workers at first-level health facilities. This paper describes the technical basis of the guidelines for the integrated management of childhood illness (IMCI) approach presented in the WHO/UNICEF training course on IMCI for outpatient health workers at such first-level facilities in developing countries. These guidelines include the most important case management and preventive interventions against pneumonia diarrhea malaria measles and malnutrition. The training course enables health workers who use the guidelines to make informed correct decisions upon the management of sick children. The guidelines have been shaped through research studies and field-testing in the Gambia Ethiopia Kenya and Tanzania as well as in studies on the clinical signs of anemia and malnutrition. These studies as well as two others from Uganda and Bangladesh are presented.

Innovative lead discovery strategies for tropical diseases.

Abstract: Lead discovery is currently a key bottleneck in the pipeline for much-needed novel drugs for tropical diseases such as malaria, tuberculosis, African sleeping sickness, leishmaniasis and Chagas disease. Here, we discuss the different approaches to lead discovery for tropical diseases and emphasize a coordination strategy that involves highly integrated partnerships and networks between scientists in academic institutions and industry in both wealthy industrialized countries and disease-endemic countries. This strategy offers the promise of reducing the inherently high attrition rate of the early stages of discovery research, thereby increasing the chances of success and enhancing cost-effectiveness.