Wright-Patterson Air Force Base

About: Wright-Patterson Air Force Base is a other organization based out in Wright-Patterson AFB, Ohio, United States. It is known for research contribution in the topics: Laser & Mach number. The organization has 5817 authors who have published 9157 publications receiving 292559 citations. The organization is also known as: Wright-Patterson AFB & FFO.

Deconstructing Cell-Free Extract Preparation for in Vitro Activation of Transcriptional Genetic Circuitry

Abstract: Recent advances in cell-free gene expression (CFE) systems have enabled their use for a host of synthetic biology applications, particularly for rapid prototyping of genetic circuits and biosensors Despite the proliferation of cell-free protein synthesis platforms, the large number of currently existing protocols for making CFE extracts muddles the collective understanding of how the extract preparation method affects its functionality A key aspect of extract performance relevant to many applications is the activity of the native host transcriptional machinery that can mediate protein synthesis However, protein yields from genes transcribed in vitro by the native Escherichia coli RNA polymerase are variable for different extract preparation techniques, and specifically low in some conventional crude extracts originally optimized for expression by the bacteriophage transcriptional machinery Here, we show that cell-free expression of genes under bacterial σ70 promoters is constrained by the rate of tran

Ability and motivation: Assessing individual factors that contribute to university retention.

Abstract: The current study explored individual differences in ability and motivation factors of retention in first-year college students. We used discrete-time survival mixture analysis to model university retention. Parents' education, gender, American College Test (ACT) scores, conscientiousness, and trait affectivity were explored as predictors of retention. Results indicate gender, ACT scores, and conscientiousness are significant predictors of retention, but parents' education level was not a significant predictor. Positive affectivity and negative affectivity also were significant predictors of university retention when added to the model. Interestingly, once affectivity was added to the model, conscientiousness was no longer a significant predictor, indicating conscientiousness may be an amalgamation of motivation and ability. Implications for research and theory are discussed.

Crystallographic Recognition Controls Peptide Binding for Bio-Based Nanomaterials

Abstract: The ability to control the size, shape, composition, and activity of nanomaterials presents a formidable challenge. Peptide approaches represent new avenues to achieve such control at the synthetic level; however, the critical interactions at the bio/nano interface that direct such precision remain poorly understood. Here we present evidence to suggest that materials-directing peptides bind at specific time points during Pd nanoparticle (NP) growth, dictated by material crystallinity. As such surfaces are presented, rapid peptide binding occurs, resulting in the stabilization and size control of single-crystal NPs. Such specificity suggests that peptides could be engineered to direct the structure of nanomaterials at the atomic level, thus enhancing their activity.

Evaluating project scheduling and due date assignment procedures: an experimental analysis

Abstract: Managers of construction projects, maintenance activities, auditing contracts, software shops, etc. are frequently faced with the task of establishing a new project's due date, which must compete with other projects already in progress or expected (forecasted) to start in the future. The study reported here addresses the problem of establishing due dates for projects which require limited resources, in an environment where new projects arrive continuously and randomly over time. A set of procedures is developed which set each project's due date when it arrives using information about the new project, current projects, and available resources. The due date setting procedures are tested via simulation with four activity scheduling heuristics that control the assignment of resources to specific activities of available projects. A second test demonstrates the performance of the due date procedures, where a portion of arriving projects have their due dates established by external forces beyond management's con...

Exceptional-point dynamics in photonic honeycomb lattices with PT symmetry

Abstract: We theoretically investigate the flow of electromagnetic waves in complex honeycomb photonic lattices with local $\mathcal{PT}$ symmetries. Such $\mathcal{PT}$ structure is introduced via a judicious arrangement of gain and loss across the honeycomb lattice, characterized by a gain and loss parameter $\ensuremath{\gamma}$. We found a class of conical diffraction phenomena where the formed cone is brighter and travels along the lattice with a transverse speed proportional to $\sqrt{\ensuremath{\gamma}}$.