Showing papers by "Wuhan University published in 2007"

Metamaterial with simultaneously negative bulk modulus and mass density.

Abstract: We report a metamaterial which simultaneously possesses a negative bulk modulus and mass density. This metamaterial is a zinc blende structure consisting of one fcc array of bubble-contained-water spheres (BWSs) and another relatively shifted fcc array of rubber-coated-gold spheres (RGSs) in epoxy matrix. The negative bulk modulus and mass density are simultaneously derived from the coexistent monopolar resonances from the embedded BWSs and dipolar resonances from the embedded RGSs. The Poisson ratio of the metamaterial also turns negative near the resonance frequency.

Size Dependence of Gas Sensitivity of ZnO Nanorods

Abstract: We report the structure, optical, and gas-sensing properties of ZnO nanorods with different diameters. Vertically well-aligned homogeneous nanorods were grown along the c-axis orientation. The shift of Raman scattering E2 (high) mode and photoluminescence (PL) spectra were used to study the dependences of nanorod diameters on the stress and oxygen vacancy. Gas sensors were prepared and tested for the detection of C2H5OH and H2S (100 ppm) in air. It was found that the thin nanorods have a significantly better sensing performance than the thick nanorods. We provide a possible explanation from the aspect of the sensing mechanism of the surface reaction process.

Multifilament Fibers Based on Dissolution of Cellulose in NaOH/Urea Aqueous Solution: Structure and Properties

Abstract: High-quality cellulose multifilaments are spun using a preliminary pilot apparatus, from the cellulose dope in an NaOH and urea aqueous solution precooled to -12 {sup o}C, by using a low-cost, simple, and environmentally friendly process. Small-angle X-ray scattering patterns indicate that the orientation of the multifilaments increase with a drawing process, leading to the improvement of their tensile strength.

Transcription factor AtMYB103 is required for anther development by regulating tapetum development, callose dissolution and exine formation in Arabidopsis.

Abstract: †These authors contributed equally to this work. Summary Downregulation of the transcription factor AtMYB103 using transgenic technology results in early tapetal degeneration and pollen aberration during anther development in Arabidopsis thaliana. This paper describes the functional analysis of the AtMYB103 gene in three knock-out mutants. Two male sterile mutants, ms188-1 and ms188-2, were generated by ethyl-methane sulfonate (EMS) mutagenesis. A map-based cloning approach was used, and ms188 was mapped to a 95.8-kb region on chromosome 5 containing an AtMYB103 transcription factor. Sequence analysis revealed that ms188-1 had a pre-mature stop codon in the AtMYB103 coding region, whereas ms188-2 had a CCT fi CTT base-pair change in the first exon of AtMYB103, which resulted in the replacement of a proline by a leucine residue in the R2R3 domain. The third mutant, an AtMYB103 transposon-tagging line, also showed a male sterile phenotype. Allelism tests indicated that MS188 and AtMYB103 belong to the same locus. Cytological observation revealed defective tapetum development and altered callose dissolution in ms188 plants. Additionally, most of the microspores in mature anthers were degraded and surviving microspores lacked exine. AtMYB103 encoded an R2R3 MYB protein that is predominantly located in the nucleus. Real-time RT-PCR analysis indicated that the callase-related gene A6 was regulated by AtMYB103. Expression of the exine formation gene MS2 was not detected in mutant anthers. These results implicate that AtMYB103 plays an important role in tapetum development, callose dissolution and exine formation in A. thaliana anthers.

Human telomeric DNA forms parallel-stranded intramolecular G-quadruplex in K+ solution under molecular crowding condition

Abstract: The G-rich strand of human telomeric DNA can fold into a four-stranded structure called G-quadruplex and inhibit telomerase activity that is expressed in 85-90% tumor cells. For this reason, telomere quadruplex is emerging as a potential therapeutic target for cancer. Information on the structure of the quadruplex in the physiological environment is important for structure-based drug design targeting the quadruplex. Recent studies have raised significant controversy regarding the exact structure of the quadruplex formed by human telomeric DNA in a physiological relevant environment. Studies on the crystal prepared in K+ solution revealed a distinct propeller-shaped parallel-stranded conformation. However, many later works failed to confirm such structure in physiological K+ solution but rather led to the identification of a different hybrid-type mixed parallel/antiparallel quadruplex. Here we demonstrate that human telomere DNA adopts a parallel-stranded conformation in physiological K+ solution under molecular crowding conditions created by PEG. At the concentration of 40% (w/v), PEG induced complete structural conversion to a parallel-stranded G-quadruplex. We also show that the quadruplex formed under such a condition has unusual stability and significant negative impact on telomerase processivity. Since the environment inside cells is molecularly crowded, our results obtained under the cell mimicking condition suggest that the parallel-stranded quadruplex may be the more favored structure under physiological conditions, and drug design targeting the human telomeric quadruplex should take this into consideration.

A MAP Approach for Joint Motion Estimation, Segmentation, and Super Resolution

Abstract: Super resolution image reconstruction allows the recovery of a high-resolution (HR) image from several low-resolution images that are noisy, blurred, and down sampled. In this paper, we present a joint formulation for a complex super-resolution problem in which the scenes contain multiple independently moving objects. This formulation is built upon the maximum a posteriori (MAP) framework, which judiciously combines motion estimation, segmentation, and super resolution together. A cyclic coordinate descent optimization procedure is used to solve the MAP formulation, in which the motion fields, segmentation fields, and HR images are found in an alternate manner given the two others, respectively. Specifically, the gradient-based methods are employed to solve the HR image and motion fields, and an iterated conditional mode optimization method to obtain the segmentation fields. The proposed algorithm has been tested using a synthetic image sequence, the "Mobile and Calendar" sequence, and the original "Motorcycle and Car" sequence. The experiment results and error analyses verify the efficacy of this algorithm

Obesity and colorectal cancer risk: A meta-analysis of cohort studies

Abstract: AIM: To evaluate the association between obesity and colorectal cancer risk. METHODS: We searched PubMed, EMBASE, and the Cochrane Library up to January 1, 2007. Cohort studies permitting the assessment of causal association between obesity and colorectal cancer, with clear definition of obesity and well-defined outcome of colorectal cancer were eligible. Study design, sample size at baseline, mean follow-up time, co-activators and study results were extracted. Pooled standardized effect sizes were calculated. RESULTS: The pooled relative risk (RR) of colorectal cancer was 1.37 (95% CI: 1.21-1.56) for overweight and obese men, 1.07 (95% CI: 0.97-1.18) for women measured by body mass index (BMI). The pooled RR for the highest vs the lowest quantiles of BMI was 1.59 (95% CI: 1.35-1.86) for men and 1.22 (95% CI: 1.08-1.39) for women at risk of colon cancer, 1.16 (95% CI: 0.93-1.46) for men and 1.23 (95% CI: 0.98-1.54) for women at risk of rectal cancer. The pooled RR for the highest vs the lowest quantiles of waist circumference was 1.68 (95% CI: 1.36-2.08) for men and 1.48 (95% CI: 1.19-1.84) for women at risk of colon cancer, 1.26 (95% CI: 0.90-1.77) for men and 1.23 (95% CI: 0.81-1.86) for women at risk of rectal cancer. The pooled RR for the highest quantiles vs the lowest quantiles of waist-to-hip ratio was 1.91 (95% CI: 1.46-2.49) for men and 1.49 (95% CI 1.23-1.81) for women at risk of colon cancer, 1.93 (95% CI: 1.19-3.13) for men and 1.20 (95% CI: 0.81-1.78) for women at risk of rectal cancer. Compared with 'normal range', the pooled RR for proximal colon cancer was 1.14 (95% CI : 0.88-1.47) for the overweight and 1.41 (95% CI: 0.66-3.01) for the obese. The pooled RR for the highest quantiles vs the lowest quantiles was 2.05 (95% CI: 1.23-3.41) with waist circumference, 1.66 (95% CI: 0.69-3.99) with waist-to-hip ratio. Compared with 'normal range', the pooled RR for distal colon cancer was 1.38 (95% CI: 1.02-1.87) for the overweight and 1.23 (95% CI: 0.80-1.90) for the obese. The pooled RR for the highest quantiles vs the lowest quantiles was 1.86 (95% CI: 1.05-3.30) with waist circumference, and 1.79 (95% CI: 0.82-3.90) with waist-to-hip ratio. CONCLUSION: Obesity is a statistically significant risk factor for colorectal cancer and the relationship is more significant in men than in women among different cancer subsites. Indexes of abdominal obesity are more sensitive than those of overall obesity.

Rice UDP-Glucose Pyrophosphorylase1 Is Essential for Pollen Callose Deposition and Its Cosuppression Results in a New Type of Thermosensitive Genic Male Sterility

Abstract: UDP-glucose pyrophosphorylase (UGPase) catalyzes the reversible production of glucose-1-phosphate and UTP to UDP-glucose and pyrophosphate. The rice (Oryza sativa) genome contains two homologous UGPase genes, Ugp1 and Ugp2. We report a functional characterization of rice Ugp1, which is expressed throughout the plant, with highest expression in florets, especially in pollen during anther development. Ugp1 silencing by RNA interference or cosuppression results in male sterility. Expressing a double-stranded RNA interference construct in Ugp1-RI plants resulted in complete suppression of both Ugp1 and Ugp2, together with various pleiotropic developmental abnormalities, suggesting that UGPase plays critical roles in plant growth and development. More importantly, Ugp1-cosuppressing plants contained unprocessed intron-containing primary transcripts derived from transcription of the overexpression construct. These aberrant transcripts undergo temperature-sensitive splicing in florets, leading to a novel thermosensitive genic male sterility. Pollen mother cells (PMCs) of Ugp1-silenced plants appeared normal before meiosis, but during meiosis, normal callose deposition was disrupted. Consequently, the PMCs began to degenerate at the early meiosis stage, eventually resulting in complete pollen collapse. In addition, the degeneration of the tapetum and middle layer was inhibited. These results demonstrate that rice Ugp1 is required for callose deposition during PMC meiosis and bridges the apoplastic unloading pathway and pollen development.

Optimal convergence rates for the compressible navier–stokes equations with potential forces

Abstract: For the viscous and heat-conductive fluids governed by the compressible Navier–Stokes equations with an external potential force, there exist non-trivial stationary solutions with zero velocity. By combining the Lp - Lq estimates for the linearized equations and an elaborate energy method, the convergence rates are obtained in various norms for the solution to the stationary profile in the whole space when the initial perturbation of the stationary solution and the potential force are small in some Sobolev norms. More precisely, the optimal convergence rates of the solution and its first order derivatives in L2-norm are obtained when the L1-norm of the perturbation is bounded.

A Total Variation Regularization Based Super-Resolution Reconstruction Algorithm for Digital Video

Abstract: Super-resolution (SR) reconstruction technique is capable of producing a high-resolution image from a sequence of low-resolution images. In this paper, we study an efficient SR algorithm for digital video. To effectively deal with the intractable problems in SR video reconstruction, such as inevitable motion estimation errors, noise, blurring, missing regions, and compression artifacts, the total variation (TV) regularization is employed in the reconstruction model. We use the fixed-point iteration method and preconditioning techniques to efficiently solve the associated nonlinear Euler-Lagrange equations of the corresponding variational problem in SR. The proposed algorithm has been tested in several cases of motion and degradation. It is also compared with the Laplacian regularization-based SR algorithm and other TV-based SR algorithms. Experimental results are presented to illustrate the effectiveness of the proposed algorithm.

Multilayered Nanocrystalline SnO2 Hollow Microspheres Synthesized by Chemically Induced Self-Assembly in the Hydrothermal Environment

Abstract: Multilayered nanocrystalline SnO2 hollow microspheres (HS−SnO2) were synthesized by chemically induced self-assembly in the hydrothermal environment. First, multilayered spherical SnO2−C composite was produced through a condensation polymerization and carbonization of sucrose accompanied by hydrolysis of SnCl4 in the hydrothermal reaction. Then, the HS−SnO2were obtained by removal of carbon via calcination. The as-prepared HS−SnO2 exhibit good electrochemical performance as the anode material in lithium ion batteries. Since this synthetic route is simple, convenient, and “green”, it is possible to extend this synthetic method to preparation of a wide range of the multilayered hollow spheres of metal oxides for functional material applications.