Wuhan University

About: Wuhan University is a education organization based out in Wuhan, China. It is known for research contribution in the topics: Population & Feature extraction. The organization has 92849 authors who have published 92882 publications receiving 1691049 citations. The organization is also known as: WHU & Wuhan College.

AID: A Benchmark Data Set for Performance Evaluation of Aerial Scene Classification

Abstract: Aerial scene classification, which aims to automatically label an aerial image with a specific semantic category, is a fundamental problem for understanding high-resolution remote sensing imagery. In recent years, it has become an active task in the remote sensing area, and numerous algorithms have been proposed for this task, including many machine learning and data-driven approaches. However, the existing data sets for aerial scene classification, such as UC-Merced data set and WHU-RS19, contain relatively small sizes, and the results on them are already saturated. This largely limits the development of scene classification algorithms. This paper describes the Aerial Image data set (AID): a large-scale data set for aerial scene classification. The goal of AID is to advance the state of the arts in scene classification of remote sensing images. For creating AID, we collect and annotate more than 10000 aerial scene images. In addition, a comprehensive review of the existing aerial scene classification techniques as well as recent widely used deep learning methods is given. Finally, we provide a performance analysis of typical aerial scene classification and deep learning approaches on AID, which can be served as the baseline results on this benchmark.

Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α

Abstract: Heterozygous mutations in the gene encoding isocitrate dehydrogenase-1 (IDH1) occur in certain human brain tumors, but their mechanistic role in tumor development is unknown. We have shown that tumor-derived IDH1 mutations impair the enzyme's affinity for its substrate and dominantly inhibit wild-type IDH1 activity through the formation of catalytically inactive heterodimers. Forced expression of mutant IDH1 in cultured cells reduces formation of the enzyme product, alpha-ketoglutarate (alpha-KG), and increases the levels of hypoxia-inducible factor subunit HIF-1alpha, a transcription factor that facilitates tumor growth when oxygen is low and whose stability is regulated by alpha-KG. The rise in HIF-1alpha levels was reversible by an alpha-KG derivative. HIF-1alpha levels were higher in human gliomas harboring an IDH1 mutation than in tumors without a mutation. Thus, IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.

Organic host materials for phosphorescent organic light-emitting diodes

Abstract: Phosphorescent organic light-emitting diodes (PhOLEDs) unfurl a bright future for the next generation of flat-panel displays and lighting sources due to their merit of high quantum efficiency compared with fluorescent OLEDs. This critical review focuses on small-molecular organic host materials as triplet guest emitters in PhOLEDs. At first, some typical hole and electron transport materials used in OLEDs are briefly introduced. Then the hole transport-type, electron transport-type, bipolar transport host materials and the pure-hydrocarbon compounds are comprehensively presented. The molecular design concept, molecular structures and physical properties such as triplet energy, HOMO/LUMO energy levels, thermal and morphological stabilities, and the applications of host materials in PhOLEDs are reviewed (152 references).

Positive RT-PCR Test Results in Patients Recovered From COVID-19.

Abstract: This case series describes reverse transcriptase–polymerase chain reaction (RT-PCR) test results in 4 health professionals discharged from hospitalization or quarantine after 2 negative RT-PCR test results and resolution of clinical COVID-19 infection.