Institution
Wuhan University
Education•Wuhan, China•
About: Wuhan University is a education organization based out in Wuhan, China. It is known for research contribution in the topics: Population & Feature extraction. The organization has 92849 authors who have published 92882 publications receiving 1691049 citations. The organization is also known as: WHU & Wuhan College.
Papers published on a yearly basis
Papers
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TL;DR: An AI system that automatically analyzes CT images and provides the probability of infection to rapidly detect COVID-19 pneumonia and is able to overcome a series of challenges in this particular situation and deploy the system in four weeks.
266 citations
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TL;DR: Observations imply that the NEAT1 modulated the expression of E2F3 gene by acting as a ceRNA, which may build up the missing link between the regulatory miRNA network and NSCLC progression.
Abstract: // Chengcao Sun 1 , Shujun Li 1, 2 , Feng Zhang 1 , Yongyong Xi 1 , Liang Wang 1 , Yongyi Bi 1 , Dejia Li 1 1 Department of Occupational and Environmental Health, School of Public Health, Wuhan University, Wuhan, P. R. China 2 Wuhan Hospital for the Prevention and Treatment of Occupational Diseases, Wuhan, P. R. China Correspondence to: Dejia Li, email: lodjlwhu@sina.com Keywords: long non-coding RNA NEAT1 (lncRNA NEAT1), hsa-miRNA-377-3p (miR-377-3p), E2F3 , non-small cell lung cancer (NSCLC), tumorigenesis Received: February 16, 2016 Accepted: May 05, 2016 Published: June 16, 2016 ABSTRACT Recently, the long non-coding RNA (lncRNA) NEAT1 has been identified as an oncogenic gene in multiple cancer types and elevated expression of NEAT1 was tightly linked to tumorigenesis and cancer progression. However, the molecular basis for this observation has not been characterized in progression of non-small cell lung cancer (NSCLC). In our studies, we identified NEAT1 was highly expressed in patients with NSCLC and was a novel regulator of NSCLC progression. Patients whose tumors had high NEAT1 expression had a shorter overall survival than patients whose tumors had low NEAT1 expression. Further, NEAT1 significantly accelerates NSCLC cell growth and metastasis in vitro and tumor growth in vivo. Additionally, by using bioinformatics study and RNA pull down combined with luciferase reporter assays, we demonstrated that NEAT1 functioned as a competing endogenous RNA (ceRNA) for hsa-miR-377-3p, antagonized its functions and led to the de-repression of its endogenous targets E2F3, which was a core oncogene in promoting NSCLC progression. Taken together, these observations imply that the NEAT1 modulated the expression of E2F3 gene by acting as a ceRNA, which may build up the missing link between the regulatory miRNA network and NSCLC progression.
266 citations
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TL;DR: The results indicate the formation of well-defined fibrillar structure is a promising approach to achieving a favorable morphology in BHJ OSCs.
Abstract: A polymer fibril assembly can dictate the morphology framework, in forming a network structure, which is highly advantageous in bulk heterojunction (BHJ) organic solar cells (OSCs). A fundamental understanding of how to manipulate such a fibril assembly and its influence on the BHJ morphology and device performance is crucially important. Here, a series of donor-acceptor polymers, PBT1-O, PBT1-S, and PBT1-C, is used to systematically investigate the relationship between molecular structure, morphology, and photovoltaic performance. The subtle atom change in side chains is found to have profound effect on regulating electronic structure and self-assembly of conjugated polymers. Compared with PBT1-O and PBT1-S, PBT1-C-based OSCs show much higher photovoltaic performance with a record fill factor (FF) of 80.5%, due to the formation of optimal interpenetrating network morphology. Such a fibril network strategy is further extended to nonfullerene OSCs using a small-molecular acceptor, which shows a high efficiency of 12.7% and an FF of 78.5%. The results indicate the formation of well-defined fibrillar structure is a promising approach to achieving a favorable morphology in BHJ OSCs.
266 citations
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TL;DR: Recent progress in the synthesis, properties and applications of MoS2 and related heterostructures are reviewed, including their novel properties and functionalities as well as emerging applications, especially in the areas of light energy harvesting or conversion.
Abstract: As a two-dimensional (2D) material, molybdenum disulfide (MoS2) exhibits unique electronic and optical properties useful for a variety of optoelectronic applications including light harvesting. In this article, we review recent progress in the synthesis, properties and applications of MoS2 and related heterostructures. Heterostructured materials are developed to add more functionality or flexibility compared to single component materials. Our focus is on their novel properties and functionalities as well as emerging applications, especially in the areas of light energy harvesting or conversion. We highlight the correlation between structural properties and other properties including electronic, optical, and dynamic. Whenever appropriate, we also try to provide fundamental insight gained from experimental as well as theoretical studies. Finally, we discuss some current challenges and opportunities in technological applications of MoS2.
265 citations
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TL;DR: The state of the art and methods for the estimation of heavy metal concentrations by the use of visible and near-infrared reflectance spectroscopy are reviewed and the challenges facing the application of hyperspectral images in mapping soil contamination over large areas are discussed.
265 citations
Authors
Showing all 93441 results
Name | H-index | Papers | Citations |
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Jing Wang | 184 | 4046 | 202769 |
Jiaguo Yu | 178 | 730 | 113300 |
Lei Jiang | 170 | 2244 | 135205 |
Gang Chen | 167 | 3372 | 149819 |
Omar M. Yaghi | 165 | 459 | 163918 |
Xiang Zhang | 154 | 1733 | 117576 |
Yi Yang | 143 | 2456 | 92268 |
Thomas P. Russell | 141 | 1012 | 80055 |
Jun Chen | 136 | 1856 | 77368 |
Lei Zhang | 135 | 2240 | 99365 |
Chuan He | 130 | 584 | 66438 |
Han Zhang | 130 | 970 | 58863 |
Lei Zhang | 130 | 2312 | 86950 |
Zhen Li | 127 | 1712 | 71351 |
Chao Zhang | 127 | 3119 | 84711 |