Institution
Xi'an Jiaotong University
Education•Xi'an, China•
About: Xi'an Jiaotong University is a education organization based out in Xi'an, China. It is known for research contribution in the topics: Heat transfer & Dielectric. The organization has 85440 authors who have published 99682 publications receiving 1579683 citations. The organization is also known as: '''Xi'an Jiaotong University''' & Xi'an Jiao Tong University.
Papers published on a yearly basis
Papers
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TL;DR: The diagnosis result shows the algorithm is able to reliably recognise not only different fault categories and severities but also the compound faults, and demonstrates the superior effectiveness and practicability of the algorithm.
237 citations
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TL;DR: In this paper, the thermal properties of all-metallic sandwich structures with two-dimensional prismatic and truss cores were analyzed using measurements in conjunction with analytical modeling and numerical simulation.
237 citations
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TL;DR: Compared with normoxic preconditioning (NP), HP not only improved MSC chemotaxis and viability but also stimulated secretion of proangiogenic and mitogenic factors and advanced knowledge about SDF-1-CX CR4/CXCR7 axis as an attractive target pathway for improving the beneficial effects of MSC-based therapies for renal I/R.
Abstract: In vitro hypoxic preconditioning (HP) of mesenchymal stem cells (MSCs) could ameliorate their viability and tissue repair capabilities after transplantation into the injured tissue through yet undefined mechanisms. There is also experimental evidence that HP enhances the expression of both stromal-derived factor-1 (SDF-1) receptors, CXCR4 and CXCR7, which are involved in migration and survival of MSCs in vitro, but little is known about their role in the in vivo therapeutic effectiveness of MSCs in renal ischemia/reperfusion (I/R) injury. Here, we evaluated the role of SDF-1-CXCR4/CXCR7 pathway in regulating chemotaxis, viability and paracrine actions of HP-MSCs in vitro and in vivo. Compared with normoxic preconditioning (NP), HP not only improved MSC chemotaxis and viability but also stimulated secretion of proangiogenic and mitogenic factors. Importantly, both CXCR4 and CXCR7 were required for the production of paracrine factors by HP-MSCs though the former was only responsible for chemotaxis while the latter was for viability. SDF-1α expression was upregulated in postischemic kidneys. After 24 h systemical administration following I/R, HP-MSCs but not NP-MSCs were selectively recruited to ischemic kidneys and this improved recruitment was abolished by neutralization of CXCR4, but not CXCR7. Furthermore, the increased recruitment of HP-MSCs was associated with enhanced functional recovery, accelerated mitogenic response, and reduced apoptotic cell death. In addition, neutralization of either CXCR4 or CXCR7 impaired the improved therapeutic potential of HP-MSCs. These results advance our knowledge about SDF-1-CXCR4/CXCR7 axis as an attractive target pathway for improving the beneficial effects of MSC-based therapies for renal I/R.
237 citations
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TL;DR: The developed UC-LFS platform is demonstrated to be highly sensitive and specific for sample-to-answer prognosis of HF, which holds great potential for risk assessment and health monitoring of post-treatment patients at home.
Abstract: Heart failure (HF) is the end-stage of cardiovascular diseases, which is associated with a high mortality rate and high readmission rate. Household early diagnosis and real-time prognosis of HF at bedside are of significant importance. Here, we developed a highly sensitive and quantitative household prognosis platform (termed as UC-LFS platform), integrating a smartphone-based reader with multiplexed upconversion fluorescent lateral flow strip (LFS). Dual-color core–shell upconversion nanoparticles (UCNPs) were synthesized as probes for simultaneously quantifying two target antigens associated with HF, i.e., brain natriuretic peptide (BNP) and suppression of tumorigenicity 2 (ST2). With the fluorescent LFS, we achieved the specific detection of BNP and ST2 antigens in spiked samples with detection limits of 5 pg/mL and 1 ng/mL, respectively, both of which are of one order lower than their clinical cutoff. Subsequently, a smartphone-based portable reader and an analysis app were developed, which could rapi...
237 citations
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TL;DR: In this paper, a detailed three-dimensional computational model of the whole parabolic trough solar collector (PTC) system and corresponding numerical simulations by combining the Finite Volume Method (FVM) and the Monte Carlo Ray-Trace (MCRT) method were presented.
236 citations
Authors
Showing all 86109 results
Name | H-index | Papers | Citations |
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Feng Zhang | 172 | 1278 | 181865 |
Yang Yang | 164 | 2704 | 144071 |
Jian Yang | 142 | 1818 | 111166 |
Lei Zhang | 130 | 2312 | 86950 |
Yang Liu | 129 | 2506 | 122380 |
Jian Zhou | 128 | 3007 | 91402 |
Chao Zhang | 127 | 3119 | 84711 |
Bin Wang | 126 | 2226 | 74364 |
Xin Wang | 121 | 1503 | 64930 |
Bo Wang | 119 | 2905 | 84863 |
Xuan Zhang | 119 | 1530 | 65398 |
Jian Liu | 117 | 2090 | 73156 |
Andrey L. Rogach | 117 | 576 | 46820 |
Yadong Yin | 115 | 431 | 64401 |
Xin Li | 114 | 2778 | 71389 |