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Institution

Xiamen University

EducationAmoy, Fujian, China
About: Xiamen University is a education organization based out in Amoy, Fujian, China. It is known for research contribution in the topics: Catalysis & Population. The organization has 50472 authors who have published 54480 publications receiving 1058239 citations. The organization is also known as: Amoy University & Xiàmén Dàxué.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the authors predict that MoS2/AlN(GaN) van der Waals (vdW) heterostructures are sufficiently efficient photocatalysts for water splitting under visible-light irradiation based on ab initio calculations.
Abstract: Hydrogen fuel produced from water splitting using solar energy and a catalyst is a clean and renewable future energy source. Great efforts in searching for photocatalysts that are highly efficient, inexpensive, and capable of harvesting sunlight have been made for the last decade, which, however, have not yet been achieved in a single material system so far. Here, we predict that MoS2/AlN(GaN) van der Waals (vdW) heterostructures are sufficiently efficient photocatalysts for water splitting under visible-light irradiation based on ab initio calculations. Contrary to other investigated photocatalysts, MoS2/AlN(GaN) vdW heterostructures can separately produce hydrogen and oxygen at the opposite surfaces, where the photoexcited electrons transfer from AlN(GaN) to MoS2 during the photocatalysis process. Meanwhile, these vdW heterostructures exhibit significantly improved photocatalytic properties under visible-light irradiation by the calculated optical absorption spectra. Our findings pave a new way to facil...

323 citations

Journal ArticleDOI
TL;DR: There was no evidence of a difference in favourable outcomes of patients receiving endovascular therapy compared with those receiving standard medical therapy alone, and the trial was terminated early after 131 patients had been randomly assigned because of high crossover rate and poor recruitment.
Abstract: Summary Background Previous randomised trials have shown an overwhelming benefit of mechanical thrombectomy for treating patients with stroke caused by large vessel occlusion of the anterior circulation. Whether endovascular treatment is beneficial for vertebrobasilar artery occlusion remains unknown. In this study, we aimed to investigate the safety and efficacy of endovascular treatment of acute strokes due to vertebrobasilar artery occlusion. Methods We did a multicentre, randomised, open-label trial, with blinded outcome assessment of thrombectomy in patients presenting within 8 h of vertebrobasilar occlusion at 28 centres in China. Patients were randomly assigned (1:1) to endovascular therapy plus standard medical therapy (intervention group) or standard medical therapy alone (control group). The randomisation sequence was computer-generated and stratified by participating centres. Allocation concealment was implemented by use of sealed envelopes. The primary outcome was a modified Rankin scale (mRS) score of 3 or lower (indicating ability to walk unassisted) at 90 days, assessed on an intention-to-treat basis. The primary safety outcome was mortality at 90 days. Secondary safety endpoints included the rates of symptomatic intracranial haemorrhage, device-related complications, and other severe adverse events. The BEST trial is registered with ClinicalTrials.gov , NCT02441556 . Findings Between April 27, 2015, and Sept 27, 2017, we assessed 288 patients for eligibility. The trial was terminated early after 131 patients had been randomly assigned (66 patients to the intervention group and 65 to the control group) because of high crossover rate and poor recruitment. In the intention-to-treat analysis, there was no evidence of a difference in the proportion of participants with mRS 0–3 at 90 days according to treatment (28 [42%] of 66 patients in the intervention group vs 21 [32%] of 65 in the control group; adjusted odds ratio [OR] 1·74, 95% CI 0·81–3·74). Secondary prespecified analyses of the primary outcome, done to assess the effect of crossovers, showed higher rates of mRS 0–3 at 90 days in patients who actually received the intervention compared with those who received standard medical therapy alone in both per-protocol (28 [44%] of 63 patients with intervention vs 13 [25%] of 51 with standard therapy; adjusted OR 2·90, 95% CI 1·20–7·03) and as-treated (36 [47%] of 77 patients with intervention vs 13 [24%] of 54 with standard therapy; 3·02, 1·31–7·00) populations. The 90-day mortality was similar between groups (22 [33%] of 66 patients in the intervention vs 25 [38%] of 65 in the control group; p=0·54) despite a numerically higher prevalence of symptomatic intracranial haemorrhage in the intervention group. Interpretation There was no evidence of a difference in favourable outcomes of patients receiving endovascular therapy compared with those receiving standard medical therapy alone. Results might have been confounded by loss of equipoise over the course of the trial, resulting in poor adherence to the assigned study treatment and a reduced sample size due to the early termination of the study. Funding Jiangsu Provincial Special Program of Medical Science.

322 citations

Journal ArticleDOI
TL;DR: If neuropilin-2 and the growth factor VEGF-C do not come together, lymphatic vessels don’t branch apart and the immune system shuts down.
Abstract: Vascular sprouting is a key process-driving development of the vascular system. In this study, we show that neuropilin-2 (Nrp2), a transmembrane receptor for the lymphangiogenic vascular endothelial growth factor C (VEGF-C), plays an important role in lymphatic vessel sprouting. Blocking VEGF-C binding to Nrp2 using antibodies specifically inhibits sprouting of developing lymphatic endothelial tip cells in vivo. In vitro analyses show that Nrp2 modulates lymphatic endothelial tip cell extension and prevents tip cell stalling and retraction during vascular sprout formation. Genetic deletion of Nrp2 reproduces the sprouting defects seen after antibody treatment. To investigate whether this defect depends on Nrp2 interaction with VEGF receptor 2 (VEGFR2) and/or 3, we intercrossed heterozygous mice lacking one allele of these receptors. Double-heterozygous nrp2vegfr2 mice develop normally without detectable lymphatic sprouting defects. In contrast, double-heterozygote nrp2vegfr3 mice show a reduction of lymphatic vessel sprouting and decreased lymph vessel branching in adult organs. Thus, interaction between Nrp2 and VEGFR3 mediates proper lymphatic vessel sprouting in response to VEGF-C.

321 citations

Journal ArticleDOI
TL;DR: The genetic bases of rice grain shape are examined, focusing on the protein products of 13 genes that have been cloned and the chromosome locations of 15 QTLs that has been fine mapped.

321 citations

Journal ArticleDOI
TL;DR: In this paper, a few-layer Molybdenum sulfide (MoS2) polymer composite is used as broadband saturable absorber (SA) for Q-switching.
Abstract: We propose and demonstrate 1, 1.5, and 2 μm passively Q-switched fiber lasers by exploiting a few-layer Molybdenum sulfide (MoS2) polymer composite as broadband saturable absorber (SA), respectively. The few-layer MoS2 nanosheets are prepared by the liquid-phase exfoliation method, and are composited with polyvinyl alcohol (PVA). The PVA-MoS2 film is sandwiched between two fiber ferrules to form the fiber-compatible SA. The few-layer MoS2 not only shows good transparency from ultraviolet to mid-infrared spectral region, but also possesses the nonlinear saturable absorption. The modulation depth and saturation optical intensity of the PVA-MoS2 film are measured to be 1.6% and 13 MW/cm2 at 1566 nm by the balanced twin-detector technique, respectively. By further inserting the filmy PVA-MoS2 SA into the cavities of Yb-, Er- and Tm-doped fiber lasers, we achieve stable Q-switching operations at 1.06, 1.56, and 2.03 μm, respectively. The output characteristics of the Q-switched pulses at the three wavelengths have been investigated, respectively. The MoS2-based Q-switching enables the large pulse energy of ∼1 μJ with a pulse width of 1.76 μs. This is, to the best of our knowledge, the first demonstration of MoS2-based Q-switched fiber lasers in a wide wavelength range (from 1 to 2 μm). Our results experimentally confirm that the new-type 2-D material, few-layer MoS2, is a promising broadband SA to Q-switch fiber lasers covering all major wavelengths from near- to mid-infrared region.

320 citations


Authors

Showing all 50945 results

NameH-indexPapersCitations
Zhong Lin Wang2452529259003
Lei Jiang1702244135205
Yang Gao1682047146301
William A. Goddard1511653123322
Rui Zhang1512625107917
Xiaoyuan Chen14999489870
Fuqiang Wang145151895014
Galen D. Stucky144958101796
Shu-Hong Yu14479970853
Wei Huang139241793522
Bin Liu138218187085
Jie Liu131153168891
Han Zhang13097058863
Lei Zhang130231286950
Jian Zhou128300791402
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023248
2022942
20216,782
20205,710
20194,982
20184,057