Institution
Yahoo!
Company•London, United Kingdom•
About: Yahoo! is a company organization based out in London, United Kingdom. It is known for research contribution in the topics: Population & Web search query. The organization has 26749 authors who have published 29915 publications receiving 732583 citations. The organization is also known as: Yahoo! Inc. & Maudwen-Yahoo! Inc.
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TL;DR: Patients who underwent patellar resurfacing experienced anterior knee pain and satisfaction with the arthroplasty procedure that were equivalent to those experienced by patients whose patella was not resurfaced; however, these patients underwent significantly fewer additional surgical procedures.
Abstract: Background: Treatment of the patella during total knee replacement is an area of continuing debate. We performed a meta-analysis of randomized controlled trials to address the hypothesis that patellar resurfacing in primary total knee replacement improved patient outcome.
Methods: Randomized controlled trials comparing patellar resurfacing with nonresurfacing in primary total knee replacement were included. The primary outcomes analyzed were knee scores, anterior knee pain, and patient satisfaction. We also investigated the prevalence of complications, revision surgery related specifically to the patellofemoral joint, the infection rate, operative time, and radiographic appearance.
Results: Sixteen randomized controlled trials assessing 3465 knee replacements were eligible; 1710 procedures included patellar resurfacing and 1755 did not. The knee component of the Knee Society Score was significantly higher in the resurfacing group (p = 0.005); however, no significant difference was observed for the function component of the Knee Society Score or for any other reported knee score. Anterior knee pain was reported in 13% of resurfaced knees and in 24% of nonresurfaced knees; this difference was not significant (p = 0.1). Patients were satisfied with the outcome after 485 (90%) of 539 procedures that included patellar resurfacing compared with 488 (89%) of 548 that did not; this difference was not significant. There were ninety-three reported patellofemoral complications in the resurfacing group and 205 in the nonresurfacing group; this difference was significant (p = 0.02) in a random-effect model. The rate of reoperation because of anterior knee pain (p < 0.00001) and the rate of reoperation because of any patellofemoral complication (p = 0.002) were significantly higher in the nonresurfaced group. No differences were found in the analyses of infection rate, operative time, or radiographic appearance.
Conclusions: Patients who underwent patellar resurfacing experienced anterior knee pain and satisfaction with the arthroplasty procedure that were equivalent to those experienced by patients whose patella was not resurfaced; however, these patients underwent significantly fewer additional surgical procedures. Further long-term follow-up of modern prostheses in randomized studies measuring outcome with a patella-specific score is needed.
142 citations
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06 Aug 2006TL;DR: This work proposes to incorporate prior knowledge of cluster membership for document cluster analysis and develops a novel semi-supervised document clustering model that reveals remarkable performance improvements with very limited training samples, and is a very effective semi- supervised classification tool.
Abstract: Document clustering is an important tool for text analysis and is used in many different applications. We propose to incorporate prior knowledge of cluster membership for document cluster analysis and develop a novel semi-supervised document clustering model. The method models a set of documents with weighted graph in which each document is represented as a vertex, and each edge connecting a pair of vertices is weighted with the similarity value of the two corresponding documents. The prior knowledge indicates pairs of documents that known to belong to the same cluster. Then, the prior knowledge is transformed into a set of constraints. The document clustering task is accomplished by finding the best cuts of the graph under the constraints. We apply the model to the Normalized Cut method to demonstrate the idea and concept. Our experimental evaluations show that the proposed document clustering model reveals remarkable performance improvements with very limited training samples, and hence is a very effective semi-supervised classification tool.
142 citations
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11 Nov 2004TL;DR: In this article, a software based system for facilitating streaming of media files to a device over a wide area network (WAN) includes an agent process, an authentication process, a client services process and a client process.
Abstract: A software based system for facilitating streaming of media files to a device over a wide area network (WAN) includes an agent process, an authentication process, a client services process and a client process. The agent process catalogs local media files and advises the authentication process of it's availability on the WAN and the address at which it may be contacted. The client process contacts the client services process to obtain, after authenticating with it, the WAN address of the agent process and contacts the agent process to receive information or meta-data describing the media files available for streaming. The client process obtains information for forming a URI or playlist, that it then passes to a media player to request the stream over the WAN. Alternately, the client process may direct the agent process to pass the URL to another client process on, for example, the same local area network.
142 citations
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24 Jun 2008TL;DR: In this article, the authors describe systems and methods delivering communications associated with delivery conditions in which the occurrence of the delivery condition is determined by monitoring information received from a plurality of sources via multiple communication channels.
Abstract: The disclosure describes systems and methods delivering communications associated with delivery conditions in which the occurrence of the delivery condition is determined by monitoring information received from a plurality of sources via multiple communication channels. The message delivery systems allow messages to be delivered to any “Who, What, When, Where” from any “Who, What, When, Where” upon the detection of an occurrence of one or more “Who, What, When, Where” delivery conditions. A message (which may be any data object including text-based messages, audio-based message such as voicemail or other audio such as music or video-based prerecorded messages) is delivered in accordance with delivery conditions based on any available data, including topical, spatial, temporal, and/or social data. Furthermore, because the systems coordinate delivery of messages via multiple communication channels and through multiple devices, the communication channel for delivery of a message may be dynamically determined based on the delivery conditions.
142 citations
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TL;DR: In vitro study demonstrated that upregulation of GLUT1 and HIF-1alpha was closely associated with [(18)F]FDG uptake into thymic tumor cell, whereas this relationship was not observed in GLUT3 and bcl-2.
Abstract: Purpose The usefulness of 2-[18F]-fluoro-2-deoxy-D-glucose ([18F]FDG) positron emission tomography (PET) can help predict the grade of malignancy and staging in thymic epithelial tumors. However, no satisfactory biologic explanation exists for this phenomenon. The aim of this study was to investigate the underlying biologic mechanisms of [18F]FDG uptake. Patients and Methods Forty-nine patients with thymic epithelial tumors who underwent [18F]FDG PET were included in this study. Tumor sections were stained by immunohistochemistry for glucose transporter 1 (GLUT1), glucose transporter 3 (GLUT3), hypoxia-inducible factor-1 α (HIF-1α), vascular endothelial growth factor (VEGF), microvessels (CD31 and CD34), cell cycle control marker (p53), and apoptosis marker (bcl-2). We also conducted an in vitro study of [18F]FDG uptake in a thymic tumor cell line. Results There was a positive correlation between [18F]FDG uptake and GLUT1 (P < .0001), HIF-1α (P = .0036), VEGF (P < .0001), microvessel density (MVD; P < .00...
142 citations
Authors
Showing all 26766 results
Name | H-index | Papers | Citations |
---|---|---|---|
Ashok Kumar | 151 | 5654 | 164086 |
Alexander J. Smola | 122 | 434 | 110222 |
Howard I. Maibach | 116 | 1821 | 60765 |
Sanjay Jain | 103 | 881 | 46880 |
Amirhossein Sahebkar | 100 | 1307 | 46132 |
Marc Davis | 99 | 412 | 50243 |
Wenjun Zhang | 96 | 976 | 38530 |
Jian Xu | 94 | 1366 | 52057 |
Fortunato Ciardiello | 94 | 695 | 47352 |
Tong Zhang | 93 | 414 | 36519 |
Michael E. J. Lean | 92 | 411 | 30939 |
Ashish K. Jha | 87 | 503 | 30020 |
Xin Zhang | 87 | 1714 | 40102 |
Theunis Piersma | 86 | 632 | 34201 |
George Varghese | 84 | 253 | 28598 |