Yaşar University

About: Yaşar University is a education organization based out in Izmir, Turkey. It is known for research contribution in the topics: Exergy & Job shop scheduling. The organization has 760 authors who have published 1436 publications receiving 20813 citations. The organization is also known as: Yaşar Üniversitesi.

Optimality condition of a nonsmooth switching control system

Abstract: In this paper, a survey and refinement of recent results in discrete optimal control theory are presented. The step control problem depending on a parameter is investigated. Nonsmoothness of the cost function φ is assumed and new versions of the discrete maximum principle for the step control problem are derived.

What is wrong with private shopping sites? – evidence from turkey

Abstract: Since 2008, private shopping sites have been amongst the leading business models in the world. However, with the growing number of these companies, there are some problems which are declared by the customers through online platforms. Hence, this study provides evidence from Turkey through the examination of the customer complaints from the leading private shopping sites. In this regard, 1,014 customer complaints were analyzed for the period of three months (April, May and June 2013) from the popular online platform “sikayetvar.com”. The findings reveal that private shopping sites have same types of customer complaints which occur mainly due to problems in the logistics capabilities of the companies. However, number of complaints differs significantly according to private shopping sites and months. This study contributes to literature through identification of variations in the number and category of complaints across months and among private shopping sites. Additionally, it provides managerial implications for private shopping sites to improve the logistics capabilities and other facilities

Two-dimensional polynomial type canonical relaxation oscillator model for p53 dynamics.

Abstract: p53 network, which is responsible for DNA damage response of cells, exhibits three distinct qualitative behaviours; low state, oscillation and high state, which are associated with normal cell cycle progression, cell cycle arrest and apoptosis, respectively. The experimental studies demonstrate that these dynamics of p53 are due to the ATM and Wip1 interaction. This paper proposes a simple two-dimensional canonical relaxation oscillator model based on the identified topological structure of ATM and Wip1 interaction underlying these qualitative behaviours of p53 network. The model includes only polynomial terms that have the interpretability of known ATM and Wip1 interaction. The introduced model is useful for understanding relaxation oscillations in gene regulatory networks. Through mathematical analysis, we investigate the roles of ATM and Wip1 in forming of these three essential behaviours, and show that ATM and Wip1 constitute the core mechanism of p53 dynamics. In agreement with biological findings, we show that Wip1 degradation term is a highly sensitive parameter, possibly related to mutations. By perturbing the corresponding parameters, our model characterizes some mutations such as ATM deficiency and Wip1 overexpression. Finally, we provide intervention strategies considering our observation that Wip1 seems to be an important target to conduct therapies for these mutations.

Media Framing of Climate Change Action in Carbon Locked-in Developing Countries: Adaptation or Mitigation?

Abstract: As the public draws most of its information on scientific issues from the media, studies of media coverage of climate change have proliferated. Here, we analyze whether newspapers in developing cou...