•Journal•ISSN: 2211-3835
Acta Pharmaceutica Sinica B
Elsevier BV
About: Acta Pharmaceutica Sinica B is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Medicine & Chemistry. It has an ISSN identifier of 2211-3835. It is also open access. Over the lifetime, 1657 publications have been published receiving 53311 citations. The journal is also known as: APSB.
Topics: Medicine, Chemistry, Cancer research, Drug delivery, In vivo
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TL;DR: This study systematically analyzed all the proteins encoded by SARS-CoV-2 genes, compared them with proteins from other coronaviruses, predicted their structures, and built 19 structures that could be done by homology modeling and constructed a database of 78 commonly used anti-viral drugs.
1,680 citations
TL;DR: The role and regulation of the HIF-1α in cancer, and recent therapeutic approaches targeting this important pathway are summarized.
1,229 citations
TL;DR: The origin and structure of exosomes as well as their biological functions are outlined and specific applications of exOSomes as drug delivery systems in pharmaceutical drug development are focused on.
891 citations
TL;DR: A review of the recent advances in the field of insoluble drug delivery and business prospects covers the development of drug candidates with greater lipophilicity, high molecular weight and poor water solubility.
885 citations
TL;DR: The biochemical events and parameters involved in the metastatic process and tumor microenvironment have been targeted or can be potential targets for metastasis prevention and inhibition and this review provides an overview of them.
640 citations