Showing papers in "Acta Tropica in 2016"

TL;DR: The upturns of current treatment of Chagas disease are summarized, the increment on research and scientific publications about this topic is discussed, and an overview of the state-of-the-art research aiming to produce an alternative medication to treat T. cruzi infection is given.

TL;DR: The integration of the sterile insect technique has proven successful to manage crop pests and disease vectors, particularly tsetse flies, and is likely to prove effective against mosquito vectors,particularly once sex-separation methods are improved.

TL;DR: An up to date review of the biology and pathogenesis of N. fowleri is presented and needs for future research against this fatal infection are discussed.

TL;DR: Evaluating the role of socioeconomic and environmental factors associated with this outbreak of dengue fever in Cali, Colombia at the neighborhood level using a Geographically Weighted Regression model provides evidence to support public health strategies in allocating resources locally.

TL;DR: Evidence is found that the prevalence of Chagas disease is higher than expected in some migrant groups and that reliance on blood donor screening prevalence estimates underestimates the burden of disease.

TL;DR: The present study established that bioactive andrographolide served as a potential useful for dengue vector management.

TL;DR: A systematic review and meta-analysis to identify the seroprevalence rate of T. gondii infection among Iranian pregnant women population to achieve a comprehensive explanation of the disease condition in Iran for future use found there's a statistically significant correlation between toxoplasmosis and two risk factors including "place of residence" and "contact with cat".

TL;DR: This review covers the basic background of the current visceral leishmaniasis treatments with an emphasis on the modes of action, and describes potential new antileishmanial drug targets and pathways, and introduces recent progress on the utilization of high-throughput phenotypic screening assays to identify novel antileistmanial compounds.

TL;DR: This review approaches the problem of benzimidazole resistance in helminths in both humans and animals, focusing on the properties of the drug, the molecular mechanisms of drug resistance and how resistance is diagnosed.

TL;DR: It is postulate that CyHV-2 was the primary etiological agent responsible for this outbreak with secondary infection by A. hydrophila, and the experimental infection trials in Labeo rohita and koi carp by intraperitoneal challenge with CyHWVs failed to reproduce the disease in those co-cultured fish species.

TL;DR: This is the first study to predict the distribution of ZCL reservoir hosts in Iran, and climbers and topography variables had high contributions toward the prediction of potential distribution of the main reservoir species; therefore, as climate changes, the models should be updated periodically with novel data, and the results should be used in disease-monitoring programs.

TL;DR: This article rigorously reviews plants and other natural products used in oral health from Africa, Asia, Brazil, Mexico, Europe, and the Middle East and exposes a dire gap for more studies on clinical efficacy and toxicity.

TL;DR: Five essential oils extracted from plants demonstrated promising insect repellent activity and show promise for further development into formulations that may serve as alternatives to DEET or possibly be used as natural bio-pesticides to kill mosquitoes.

TL;DR: This review focuses on natural antimycobacterial agents from endophytes and medicinal plants of Africa, Europe, Asia, South America and Canada that may provide leads to novel and more efficacious drugs to lessen the global burden of TB and drug-resistant M. tuberculosis strains.

TL;DR: The quick, one-step, single-tube, highly sensitive loop-mediated isothermal amplification (LAMP) assay for rapid detection of Leishmania DNA from tissue materials spotted on an FTA card is established and has great potential usefulness for diagnosis and surveillance of leishmaniasis in endemic areas.

TL;DR: For the daily clinical work, tissue manifestation by parasites should be considered in cases of unspecific organ manifestations, (i.e. heart, lungs, liver), accompanied by fever and eosinophilia with or without allergic skin rashes.

TL;DR: The current evidence and the results from proposed transdisciplinary research on dengue within different ecosystems will help guide the development of new vector control strategies and foster a better understanding of climate change impacts on vector-borne disease transmission.

TL;DR: It is likely that the relatively stable kdr mutation allele frequencies observed here result from balancing selection, in the form of overdominance for VG/FC genotypes and/or the effects of fluctuating environments that vary in insecticide exposure.

TL;DR: In this paper, loop-mediated isothermal amplification (LAMP) was used for the detection of Leishmania DNA in human blood or tissue samples, and three LAMP systems were developed; in two of those the primers were designed based on shared regions of the ITS1 gene among different leishmaniasis species, while the third LAMP system were derived from a newly identified repeated region in the Leishman genome.

TL;DR: Three detection methods are complementary for monitoring Giardia and Cryptosporidium in environmental waters through immunofluorescence assays, nested PCR and loop-mediated isothermal amplification.

TL;DR: Evidence is presented that the infection can be detected in filtered urine samples collected and processed in the field and subsequently assayed for the presence of parasite DNA, and DNA amplification from urine residue reveals significantly more cases of S. stercoralis infection than the current standard stool examination techniques.

TL;DR: In the clinical efficacy study, a reduction in cyst weight was observed after the administration of 40mg/kg of carvacrol during 20days in mice with cysts developed during 4 months, compared to that of those collected from control mice.

TL;DR: A rapid and specific nested-PCR for detection of DENV, CHIKV and ZIKV infection in the same sample is reported, which might be a useful and an inexpensive tool for Detection of these infections in regions where these arboviruses co-circulate.

TL;DR: Response of M2 macrophages emerge as an alternative for a better understanding of the innate immunity in the polar forms of leprosy, highlighting the role of cytokines, arginase 1 and costimulatory molecules in the repair and suppressive responses in the lepromatous form of the disease.

TL;DR: It is confirmed that these morphologically close species are valid, and that geometric morphometrics can considerably increase the reliability of morphological identification.

TL;DR: It is confirmed that schistosomiasis transmission is focal in nature as indicated by significant S. haematobium cases and infection intensity clusters (p<0.05) in the study area.

TL;DR: It may be hypothesized that there are large number of asymptomatic dengue infections in the community as compared to reported symptomatic cases in Delhi, and this study suggests that out of the total population screened, 10.6% d Dengue infection was either primary or secondary.

TL;DR: In this paper, the authors provided an epidemiological description of human leptospirosis cases over a 9-year period (2004-2012) and disease relationship with meteorological, geographical, and demographical information.

TL;DR: The results demonstrate that IRS can have both an immediate and sustained effect on reducing adult and immature A. aegypti populations and should be considered as an adult mosquito control strategy by dengue vector control programs.

TL;DR: The scientific literature of the last 25 years and estimated country-wide prevalence rates for South-East Asia are reviewed to summarise what is known today about the prevalence of S. stercoralis in South- East Asia and to ascertain the risk factors and diagnostic methods most commonly applied.