scispace - formally typeset
Search or ask a question
JournalISSN: 0300-8924

Acta vitaminologica et enzymologica 

De Gruyter
About: Acta vitaminologica et enzymologica is an academic journal. The journal publishes majorly in the area(s): Vitamin & Kynurenine. It has an ISSN identifier of 0300-8924. Over the lifetime, 281 publications have been published receiving 1773 citations.


Papers
More filters
Journal Article
TL;DR: The results indicate that the efficacies of superoxide dismutase and ascorbic acid for catalyzing the decay ofsuperoxide radical in animal tissues are similar.
Abstract: The second order rate constant for the reaction between ascorbic acid and superoxide at pH 7.4 using the xanthine-xanthine oxidase system was estimated to be 5.4 x 10(6) M-1 sec-1. The results indicate that the efficacies of superoxide dismutase and ascorbic acid for catalyzing the decay of superoxide radical in animal tissues are similar. The significance of ascorbic acid as a scavenger of superoxide is discussed from the point of view of evolution of ascorbic acid synthesizing capacity in the terrestrial vertebrates.

53 citations

Journal Article
TL;DR: Experiments in rats have shown that treatments which increase free tryptophan in serum (in respect to competing amino acids) also increase brain tryPTophan and serotonin turnover, and in man the administration of an amino acid mixture lacking trytophan produces a marked depletion in serum tryptophile concentration.
Abstract: Changes in the synthesis rate of brain serotonin are positively correlated with changes in the concentration of brain tryptophan, indicating that the concentration of tryptophan in the whole brain reflects that at sites of serotonin synthesis. In turn, the concentration of brain tryptophan is positively correlated with that of free serum tryptophan (tryptophan is the only amino acid bound to serum proteins) and negatively to that of other amino acids competing with tryptophan for the same transport from blood to brain. Consistently, experiments in rats have shown that treatments which increase free tryptophan in serum (in respect to competing amino acids) also increase brain tryptophan and serotonin turnover. Conversely, the ingestion of diets containing all amino acids except tryptophan cause a dramatic fall in free serum tryptophan and a parallel decline in brain tryptophan and serotonin synthesis. In man the administration of an amino acid mixture lacking trytophan produces a marked depletion in serum tryptophan concentration.

49 citations

Journal Article
TL;DR: The presence of bovine serum albumin drastically reduces the vitamin oxidation rate regardless of stereoisomerism, and the interaction with alkaline phosphatase, an enzyme inhibited by preincubation with vitamin C, does not modify significantly the stability in the experimental conditions used.
Abstract: Different water purity provokes a great variation of the stability of ascorbic acid and isoascorbic acid solutions. The effect of temperature on ascorbate aerobic oxidation was assessed by means of Arrhenius plots from which thermodynamic parameters were derived. The presence of bovine serum albumin drastically reduces the vitamin oxidation rate regardless of stereoisomerism. On the other hand the interaction with alkaline phosphatase, an enzyme inhibited by preincubation with vitamin C, does not modify significantly the stability in the experimental conditions used.

44 citations

Journal Article
Kotake Y, Ueda T, Mori T, Igaki S, M. Hattori 
TL;DR: It is found that saturated fat increased urinary xanthurenic acid in vitamin B6 deficiency and reduced insulin activity, and the antigenicity of xanthUREnic acid-insulin was almost same as native insulin.
Abstract: 1) Xanthurenic acid-insulin complex reduced insulin activity. 2) The antigenicity of xanthurenic acid-insulin was almost same as native insulin. 3) Saturated fat increased urinary xanthurenic acid in vitamin B6 deficiency.

41 citations

Network Information
Related Journals (5)
Cellular and Molecular Life Sciences
32.2K papers, 865K citations
70% related
Biochemical Pharmacology
29.2K papers, 1.1M citations
69% related
Clinica Chimica Acta
22.7K papers, 557.3K citations
69% related
Biochemical Journal
54.1K papers, 2.7M citations
69% related
Journal of Nutrition
24.2K papers, 1.2M citations
68% related
Performance
Metrics
No. of papers from the Journal in previous years
YearPapers
198533
198433
198321
198229
198120
19807