Showing papers in "American Heart Journal in 2008"

TL;DR: Apical ballooning syndrome should be included in the differential diagnosis of patients with an apparent acute coronary syndrome with left ventricular regional wall motion abnormality and absence of obstructive coronary artery disease, especially in the setting of a stressful trigger.

TL;DR: Women with a history of preeclampsia/eClampsia have approximately double the risk of early cardiac, cerebrovascular, and peripheral arterial disease, and cardiovascular mortality and further research is needed to determine the mechanisms underlying these associations and to identify effective prevention strategies.

TL;DR: Overweight and obesity were associated with lower all-cause and cardiovascular mortality rates in patients with CHF and were not associated with increased mortality in any study.

TL;DR: Nonadherence to cardioprotective medications is common in clinical practice and associated with a broad range of adverse outcomes, and should be a target for quality improvement interventions to maximize the outcomes of patients with CAD.

TL;DR: Obesity increased the risk of developing AF by 49% in the general population, and the risk escalated in parallel with increased BMI, demonstrating that AF evolves as yet another pathogenetic factor by which obesity may increase cardiovascular and cerebrovascular events.

TL;DR: Application of these findings with a simple algorithm can distinguish patients who are low risk from those at high risk who may benefit from closer monitoring and aggressive evidence-based treatment.

TL;DR: The National Registry of Myocardial Infarction (NHRI) has been used to study the characteristics and hospital mortality of patients with either ST elevation (STEMI) or non-ST elevation (NSTEMI). as mentioned in this paper found that the proportion of NSTEMI increased from 14.2% to 59.1% from 1990 to 2006.

TL;DR: Hypoalbuminemia is common in HF and is independently associated with increased risk of death in HF, and further investigation of pathophysiologic mechanisms underlying hypo albuminemia in HF is warranted.

TL;DR: The IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) is a multicenter, randomized, double-blind, active-control trial designed to test the hypothesis that the addition of ezetimibe to statin therapy will translate into increased clinical benefit on cardiovascular outcomes relative to simvastatin monotherapy in patients with ACS.

TL;DR: In men and women with CHD, peak Vo(2) remains an independent predictor of all-cause and cardiovascular-specific mortality.

TL;DR: The angiogenic cell therapy using bone marrow mononuclear cells can induce a long-term improvement in limb ischemia, leading to extension of amputation-free interval, and the safety and efficacy are not inferior to the conventional revascularization therapies.

TL;DR: The National Registry of Myocardial Infarction (NRMI) collected data regarding reperfusion therapy, its timing and in-hospital mortality among STEMI patients from 1990 through 2006 as discussed by the authors.

TL;DR: The conventional and newer echocardiographic parameters used to evaluate LA size and function are discussed, including Doppler tissue imaging (DTI) including segmental atrial function assessment using color DTI, strain, and strain rate.

TL;DR: Atrial fibrillation is common in patients with atherothrombosis, associated with more frequent fatal and nonfatal CV outcomes, and underuse of oral anticoagulants.

TL;DR: Although calcium, phosphate, and calcium-phosphate product levels exhibit complex associations with traditional cardiovascular risk factors and outcomes, they may be potentially modifiable risk factors for stroke and death in community-dwelling adults.

TL;DR: Adherence to American Heart Association/American College of Cardiology practice guidelines has improved care of patients with AMI and is associated with significant reductions in in-hospital mortality rates, however, persistent gaps in overall care as well as care disparities remain and suggest the need for ongoing quality improvement efforts.

TL;DR: Evidence is provided that statin therapy may have a beneficial effect on plaque volume and composition, as assessed by noninvasive MRI, in patients with moderate hypercholesterolemia.

TL;DR: In addition to its reported rhythm-targeted and rate-targeting therapeutic actions in paroxysmal and persistent AF, dronedarone improves ventricular rate control in patients with permanent AF.

TL;DR: The novel observation of FDC pedigrees in which not all affected individuals carry the putative disease-causing LMNA mutation suggests that some protein-altering LMNA variants are not causative or that some proportion of F DC may be because of multiple causative factors.

TL;DR: Echocardiography should be systematically performed for all patients presenting with Tako-Tsubo syndrome for the detection of LVOT obstruction, with specific characteristics as compared with patients withoutLVOT obstruction.

TL;DR: The CHADS2 score is a good predictor of the stroke risk but could be improved, and adding sex, the extension of age categories and reweighing of established risk factors improved ChADS2 accuracy.

TL;DR: Current understanding of the pathophysiology of AHF is described, including a critical evaluation of the data supporting both traditional and novel mechanisms, and a framework for integrating these mechanisms into an overall model ofAHF is suggested.

TL;DR: Results from randomized trials are still needed to definitely establish the role of drug-eluting stent implantation instead of the reference treatment, surgery, and it is shown that disease location predicted MACE and TVR, whereas high-risk features predicted death.

TL;DR: C-reactive protein is associated with decreased HRV, even after controlling for traditional CAD risk factors, and Autonomic dysregulation leading to inflammation may represent one pathway through which traditional risk factors promote development of CAD.

TL;DR: This is the largest trial yet conducted in Chagas' disease and will clarify the role of trypanocidal therapy in preventing cardiac disease progression and death.

TL;DR: The results of this prospective, population-based study show that current and former smoking of cigarettes are associated with increased risk of atrial fibrillation.

TL;DR: A multivariable score based on readily available CPX responses provides a simple and integrated method that powerfully predicts outcomes in patients with HF.

TL;DR: The FREEDOM Trial is an international study designed to define the optimal revascularization strategy for the diabetic patient with multivessel coronary disease.

TL;DR: Clopidogrel in mild or moderate CKD patients may not have the same beneficial effect as it does in patients with normal renal function, but was not associated with a greater relative risk of bleeding based on renal function.

TL;DR: There have been significant increases in incidence of PPM implantation over 30 years, and PPM recipients have had an age-independent increase in comorbidities relative to the underlying population, especially over the past 15 years.