Showing papers in "American Heart Journal in 2013"

TL;DR: In this study, iron deficiency is common in patients with chronic HF, relates to disease severity, and is a strong and independent predictor of outcome.

TL;DR: If low-dose methotrexate reduces cardiovascular events, CIRT would provide a novel therapeutic approach for the secondary prevention of heart attack, stroke, and cardiovascular death.

TL;DR: The liberal transfusion strategy was associated with a trend for fewer major cardiac events and deaths than a more restrictive strategy, and these results support the feasibility of and the need for a definitive trial.

TL;DR: The CANVAS trial as discussed by the authors evaluated the effects of canagliflozin on the risk of cardiovascular disease and to assess safety and tolerability in patients with inadequately controlled T2DM and increased cardiovascular risk.

TL;DR: For instance, this article found that posttraumatic stress disorder is associated with increased risk for incident CHD, even after adjusting for depression and other covariates, and these results suggest that it may be a modifiable risk factor for CHD.

TL;DR: Investigations of the innate and adaptive immune responses occurring in RA may delineate novel mechanisms in the pathogenesis of heart disease and help identify novel therapeutic targets for the prevention and treatment ofHeart disease.

TL;DR: Among patients prescribed statins, women and nonwhite patients are at increased risk for nonadherence, and further research is needed to identify interventions best suited to improve adherence in these populations.

TL;DR: It is expected that LEADER will provide conclusive data regarding the cardiovascular safety of liraglutide relative to the current standard of usual care for a global population of patients with T2DM.

TL;DR: A benefit of IVUS optimized DES implantation was observed in complex lesions in the post-procedure minimal lumen diameter and no statistically significant difference was found in MACE up to 24 months.

TL;DR: The primary study hypothesis is that PCDT will reduce the proportion of patients who develop postthrombotic syndrome within 2 years by one-third, assessed using the Villalta Scale.

TL;DR: In this article, the authors performed a retrospective analysis of medical records of 1,605 patients referred to the Cleveland Clinic Preventive Cardiology Section for statin intolerance between January 1995 and March 2010 with at least a 6-month follow-up.

TL;DR: Older patients with PAD undergoing major LE amputation still face a slightly high mortality risk, with almost half of all patients withPAD dying within a year of major Le amputation.

TL;DR: In this cohort of high-risk patients, preoperative hs-cTnT concentrations were significantly associated with postoperative MI and long-term mortality after noncardiac surgery.

TL;DR: Only a modest number of additional person-years of follow-up were ascertained from this reevaluation of CV end points in RECORD, and HRs and CIs from these analyses showed similar treatment effects of rosiglitazone compared with the original RECORD results.

TL;DR: Frailty is independently associated with risk of HF in older adults and results were comparable across age, sex, and race, and in sub-groups based on diabetes mellitus or cardiovascular disease at baseline.

TL;DR: Early treatment of atrial fibrillation for stroke prevention trial (EAST) as mentioned in this paper was designed to test whether an early, modern rhythm control therapy can reduce cardiovascular complications in patients with Atrial Fibrillation.

TL;DR: Among women with signs and symptoms of ischemia, nonobstructive CAD is common and associated with adverse outcomes over the longer term, and the new WISE angiographic score appears to be useful for risk prediction in this population.

TL;DR: Clinically and statistically significant increases in mortality were observed as early as at 30 days post-ACS and persisted at 1 year and anemia in patients with ACS is independently associated with a significantly increased risk of early and late mortality.

TL;DR: The meta-analysis indicates that higher PTH concentrations are associated with increased risk of CVD events, and specifically in whites with a mean age between 55 and 75 years.

TL;DR: The PURE study as mentioned in this paper investigated associations between social, behavioural, genetic, and environmental factors and cardiovascular diseases in 17 countries and found that modest differences exist between the PURE household population and national data for the indicators studied.

TL;DR: Women with stable angina and nonobstructive CAD are 3 times more likely to experience a cardiac event within the first year of cardiac catheterization than men, and a prospective trial to examine the impact of medical therapy on MACE is warranted.

TL;DR: The TECOS trial as mentioned in this paper evaluated the effects of adding sitagliptin to usual diabetes care on cardiovascular outcomes and clinical safety, and the primary composite cardiovascular endpoint is time to the first occurrence of cardiovascular death, non-fatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina.

TL;DR: In patients with CAD and without tachyarrhythmia, prospectively triggered coronary CTA provides image quality and diagnostic accuracy comparable with retrospectively gated CTA, but at a much lower radiation dose.

TL;DR: The data suggest that sST2 may be more useful for monitoring long-term heart failure, and galectin-3 may beMore useful for the diagnosis of heart failure remodeling.

TL;DR: Acute factors, rather than preexisting cardiovascular comorbid conditions, are associated with increased risk for newly diagnosed atrial fibrillation during sepsis, suggesting that mechanisms of newly diagnosed AF during Sepsis may differ from the general population of patients with AF.

TL;DR: Six weeks of supplementation with 2,000 IU oral VitD3 increased 25-hydroxyvitamin D3 levels and decreased PRA and plasma renin concentration and no significant changes were observed in secondary outcome parameters, including N-terminal pro-B-type natriuretic peptide natriurestic peptides and fibrosis markers.

TL;DR: Cardiac catheterization reports generated by the Department of Veterans Affairs' CART Program demonstrate excellent data validity, superior completeness, and a trend toward more timely availability to referring providers relative to cardiacCatheterization laboratory reports generated prior to Cart Program implementation.

TL;DR: Routine screening for undiagnosed diabetes may be useful since these patients seem to have worse short-term outcomes and deserve consideration of alternative management strategies.

TL;DR: This randomized clinical study suggested that PCB provided much better clinical and angiographic outcomes than did conventional balloon angioplasty in patients with BMS-ISR and DES-ISr.

TL;DR: Conventional echo RV functional parameters are valuable to identify risk for transplant or death in children with PAH.