scispace - formally typeset
Search or ask a question

Showing papers in "American Journal of Kidney Diseases in 1996"


Journal ArticleDOI
TL;DR: The authors' data under-score the frequency and severity of coronary and valvular calcifications in dialysis patients, and illustrate the rapid progression of this calcification, drawing attention to hypertension as an important risk factor in this process.

807 citations


Journal ArticleDOI
TL;DR: Anemia, an easily reversible feature of end- stage renal disease, is an independent risk factor for clinical and echocardiographic cardiac disease, as well as mortality in end-stage renal disease patients.

736 citations


Journal ArticleDOI
TL;DR: The high prevalence ofLVH in patients with renal insufficiency prior to the need for dialysis is demonstrated, which is associated with severity of renal impairment, and two modifiable factors (systolic blood pressure and anemia) are identified as important predictors of LVH.

686 citations


Journal ArticleDOI
TL;DR: Significantly increased risk for mortality was observed in patients with RLS at the 2.5-year follow-up and Symptoms of RLS, sleep onset latency, and transferrin saturation were independently associated with premature discontinuation of dialysis.

410 citations


Journal ArticleDOI
TL;DR: Primary analyses of the MDRD Study suggest that a lower protein intake, but not the keto acid-amino acid supplement, retards the progression of advanced renal disease.

311 citations


Journal ArticleDOI
TL;DR: It was concluded that SEP is one of the most serious complications of CAPD, and constant surveillance is necessary to detect SEP in patients during CAPD.

256 citations


Journal ArticleDOI
TL;DR: These epidemiologic observations have thoroughly dispelled the mistaken belief that renal prognosis was benign in type II diabetes and called for intense efforts to educate the medical community and intensify research in this field.

252 citations


Journal ArticleDOI
TL;DR: It is concluded that creatinine clearance was slightly decreased in all patients with hypothyroidism, this decrease being more noticeable in elderly patients.

247 citations


Journal ArticleDOI
TL;DR: It was found serious adverse reactions to be uncommon in hemodialysis patients treated with intravenous iron dextran, and future prospective studies will help confirm this finding.

246 citations


Journal ArticleDOI
TL;DR: The Modification of Diet in Renal Disease Study results confirm previous reports indicating that hypertension in renal disease is determined by the level of renal function and suggest that hypertension is inadequately treated in more than half of patients with chronic renal disease in the United States.

234 citations


Journal ArticleDOI
TL;DR: It is concluded that mupirocin ointment at the exit site and cyclic oral rifampin are equally effective in reducing S aureus catheter infections.

Journal ArticleDOI
TL;DR: In patients with low molecular weight types the Lp(a) concentrations remain unchanged during both phases of renal disease, and as in the general population, Lp (a) is a risk factor for cardiovascular events in ESRD patients.

Journal ArticleDOI
TL;DR: Application of the Cleveland Clinic Foundation (CCF) ARF acuity score showed highly predictable outcomes when compared using the Lemeshow, Hosmer goodness-of-fit statistics, and highly reproducible results in both the prospective database and double-blinded prospective clinical trials.

Journal ArticleDOI
TL;DR: Significant racial differences in the distribution of primary glomerular lesions exists in adults who had a renal biopsy for nephrotic proteinuria, with black patients four times as likely to have FSGS as white patients.

Journal ArticleDOI
TL;DR: Although VF are relatively infrequent in long-term survivors of renal transplantation, osteopenia is a frequent finding, and a substantial proportion of women present lumbar osteoporosis, and Prednisone dosage remains the most constantly isolated risk factor.

Journal ArticleDOI
TL;DR: It is inferred that initiation of uremia therapy is delayed in inner-city residents with progressive renal failure who do not receive specialist nephrologic care, and that as a consequence these patients suffer excess short-term morbidity.

Journal ArticleDOI
TL;DR: In conclusion, IV Fe supplementation in two thirds of anemic CRF patients not receiving dialysis resulted in a significant improvement of the anemia, thus avoiding the necessity of erythropoietin or blood administration.

Journal ArticleDOI
TL;DR: Black patients with previous peritonitis, black race, and those dialyzing with standard connectors or cyclers compared with disconnect systems were more likely than whites to use a disconnect system, and the outcome of peritonococcus epidermidis-like organisms was similar to that in whites.

Journal ArticleDOI
TL;DR: Using endoluminal thrombolytic therapy and percutaneous mechanical techniques, the mean survival for catheters intended for permanent vascular access is extended to 12.7 months and 95% of theCatheters inserted for temporary use to reach their use goal.

Journal ArticleDOI
TL;DR: Fungal peritonitis is rare in the CPD population, and although it leads to significant CPD drop-out, it can be managed in many patients with antifungal therapy, early catheter removal, and temporary hemodialysis.


Journal ArticleDOI
TL;DR: The etiology of the immunologic type of HIT is suggested to involve the binding of a specific antibody for platelet factor 4-heparin complex to platelets and their consequent activation.

Journal ArticleDOI
TL;DR: The transplant clinician now has a greater choice in the selection and application of immunosuppressants in the clinic for the fine regulation of the antiallograft repertory.

Journal ArticleDOI
TL;DR: Renal papillary necrosis and chronic renal insufficiency can occur with the prolonged use of these drugs, although the prevalence of this manifestation of nonsteroidal anti-inflammatory drug nephrotoxicity is unknown.

Journal ArticleDOI
TL;DR: The modem understanding of cyst pathogenesis opens opportunities to develop treatments that may diminish or halt altogether the progression of this disease.

Journal ArticleDOI
TL;DR: Results demonstrate that phosphorus accelerates the development of parathyroid hyperplasia and secondary hyperparathyroidism in rats with renal failure, and that phosphorus restriction prevents these abnormalities independent of changes in serum ionized calcium and 1,25-(OH)2D3.

Journal ArticleDOI
TL;DR: Treatment with captopril and antiretroviral therapy might be useful in delaying the rapidly progressive renal failure characterizing HIVAN, and findings must be confirmed by randomized, double-blind, placebo-controlled trials.

Journal ArticleDOI
TL;DR: The serum prealbumin level appears to be the single best nutritional predictor of survival in ESRD patients, and correlated significantly with other measures of nutrition, including serum albumin, serum creatinine, and serum cholesterol, in both HD and PD patients.

Journal ArticleDOI
TL;DR: Bardet-Biedl syndrome has an adverse prognosis, with early onset of blindness, obesity, hypertension, and diabetes mellitus, and survival is substantially reduced.

Journal ArticleDOI
TL;DR: It is concluded that the "reverse urea hypothesis" remains a viable explanation for dialysis disequilibrium and that rapid reduction of a high urea level in and of itself predisposes to this condition.