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Showing papers in "American Journal of Kidney Diseases in 1998"



Journal ArticleDOI
TL;DR: This study concludes that a large percentage of hemodialysis patients who have a serum phosphorus level above 6.5 mg/dL and that this places them at increased risk of death, and supports the need for vigorous control of hyperphosphatemia to improve patient survival.

2,323 citations



Journal ArticleDOI
TL;DR: Mean serum creatinine values are higher in men, non-Hispanic blacks, and older persons and are lower in Mexican-Americans, and it is not clear to what extent the variability by sex, age, and age reflects normal physiological differences rather than the presence of kidney disease.

560 citations


Journal ArticleDOI
TL;DR: The data support the view that hypoalbuminemia and hypocholesterolemia are negative acute-phase responses to inflammatory stimuli and suggest that efforts to identify the nature of the stimuli for cytokine production and to lower cytokine levels in hemodialysis patients might be effective in improving the survival of patients undergoing he modialysis.

532 citations


Journal ArticleDOI
TL;DR: Serum albumin was confirmed to be a useful predictor of mortality risk in hemodialysis patients; BMI was established as an independently important predictor ofortality; both serum albumin and BMI, measured at baseline, continue to possess predictive value 5 years later; the subjective caregiver classification of nutritional status "undernourished" has independent value in predicting mortality risk beyond the information gained from two other markers of nutritionalStatus.

435 citations


Journal ArticleDOI
TL;DR: Patients who shortened HD sessions did not have a higher risk of death, but those who shortened three or more in 1 month had a 20% higher risk than compliant patients, and there was a significant correlation among the measures of noncompliance.

394 citations


Journal ArticleDOI
TL;DR: It is found that although dietary protein restriction retards the rate of renal function decline, the relatively weak magnitude of this effect suggests that better therapies are needed to slow the rates of renal disease progression.

372 citations


Journal ArticleDOI
TL;DR: This study confirms the high morbidity and mortality of calcific uremic arteriolopathy producing ischemic tissue necrosis while drawing attention to significant weight loss and warfarin therapy as risk factors for the development of isChemic tissue Necrosis.

301 citations



Journal ArticleDOI
TL;DR: It is hypothesized that proinflammatory cytokines, generated in response to cardiac failure, infection, and other inflammatory stimuli, appear to play a pivotal role by causing muscle wasting, hypoalbuminemia, and anorexia as well as reduced cardiac contractility and atherosclerotic vascular disease in ESRD patients.

Journal ArticleDOI
TL;DR: An improvement in QOL indices was globally observed; this improvement was much more marked in men than in women, for unclear reasons, and older age and greater prior comorbidity diminished the beneficial effects of transplantation.

Journal ArticleDOI
TL;DR: The likelihood of a surviving infant resulting from pregnancy in dialysis patients is higher than previously observed and there is a suggestion that increased dialysis time may improve outcome.

Journal ArticleDOI
TL;DR: Administration of intravenous anaritide before and during a radiocontrast study did not reduce the incidence of RCIN in patients with preexisting chronic renal failure, with or without diabetes mellitus.

Journal ArticleDOI
TL;DR: The investigation and treatment of one patient with TRAS is described and the current diagnostic approaches and therapy in this setting are reviewed.

Journal ArticleDOI
TL;DR: Optimal pre-end-stage renal disease care involves early interventions aimed at delaying progression of chronic renal failure, judicious management of uremic complications, timely placement of vascular access, timely initiation of renal replacement therapy, and implementation of educational programs targeted at maximum rehabilitation.

Journal ArticleDOI
TL;DR: It is suggested that oxygen free radicals contribute to ionic, high-osmolality contrast medium nephrotoxicity in hypomagnesemic patients with mild renal disease and that magnesium attenuates the neph rotoxicity mediated by oxygenFree radicals.

Journal ArticleDOI
TL;DR: There appears to be a renal salt-wasting syndrome with overlapping clinical features that make it indistinguishable from the syndrome of inappropriate secretion of antidiuretic hormone (SIADH), except possibly for extracellular volume depletion.

Journal ArticleDOI
TL;DR: Inflammation and positive acute-phase reactants, produced in response to inflammation, have been identified as important contributors to hypoalbuminemia in dialysis patients and markers of inflammation and peritoneal albumin loss as independent predictors in PD patients.

Journal ArticleDOI
TL;DR: Measurement of glomerular filtration rate (GFR) following the injection of one of several suitable marker substances remains the best method to determine the severity of renal insufficiency as well as its rate of progression, but the expense of these procedures continues to restrict their use.

Journal ArticleDOI
TL;DR: The clinical anecdotes demonstrate the short-term clinical efficacy of mycophenolate mofetil treatment and suggest that MMF may have major steroid-sparing effects and might represent an alternative to cyclosporin A in appropriate patients.

Journal ArticleDOI
TL;DR: Hepatitis C virus infection increased the risk for death among chronic dialysis patients who were positive for the HCV antibody and HCV RNA compared with negative patients, and the measures used to prevent and treat HCV infection were assessed.

Journal ArticleDOI
TL;DR: The incidence of CH was high, and its prognosis was poor, in patients undergoing maintenance HD, and there were no significant differences in the serum levels of albumin and cholesterol or the total dose of heparin during HD sessions between groups.

Journal ArticleDOI
Andrew S. Levey1
TL;DR: This month’s issue of the American Journal of Kidney Diseases contains a summary of the report of the Task Force, including a description of the process used to answer this question, as well as recommendations for clinical practice and clinical research.

Journal ArticleDOI
TL;DR: There was no statistically significant difference in long-term survival when ER patients are compared with LR patients or when patients who had received emergent HD were compared with those who had not, and the financial costs of emergentHD alone merit greater promotion of ER and the psychosocial preparation and modality choice it allows.

Journal ArticleDOI
TL;DR: Although optimal duration of steroid therapy cannot be determined by this review, treatment beyond 6 months does not appear to be beneficial, since long-term renal survival in both age groups with this event was 100%.

Journal ArticleDOI
TL;DR: In this article, the authors determined the prevalence of restless legs syndrome (RLS) in all stable hemodialysis patients under long-term treatment in two dialysis centers (n = 136) and compared the clinical and biochemical findings of patients with RLS and without RLS.

Journal ArticleDOI
TL;DR: In successful pregnancies, a correlation between birth weight and dose of dialysis is found, confirming the remarkable improvement in the prognosis of pregnancy in dialysis patients in recent years.

Journal ArticleDOI
TL;DR: The lag phenomenon is described in detail, its presence during treatment in other populations is documented, and how this knowledge is used in the application of the dry-weight method of drug-free BP control in the dialysis population is described.