Showing papers in "American Journal of Kidney Diseases in 2003"

TL;DR: CKD is common and warrants improved detection and classification using standardized criteria to improve outcomes, and CCr estimates showed a steeper decline with age and were lower in non-Hispanic blacks.

TL;DR: Because MICS leads to a low body mass index, hypocholesterolemia, hypocreatininemia, and hypohomocysteinemia, a "reverse epidemiology" of cardiovascular risks can occur in dialysis patients, obesity, hypercholesterolesmia, and increased blood levels of creatinine and homocysteine appear to be protective and paradoxically associated with a better outcome.

TL;DR: Renal function correlates weakly with BNP and influences the optimal cut point for BNP, particularly in those with an eGFR less than 60 mL/min/1.73 m2.

TL;DR: Mortality and morbidity of ANCA-associated systemic vasculitis are improving compared with previous series, but remain high.

TL;DR: Results show that a low GFR per se is associated with an inflammatory state, suggesting impaired renal elimination of proinflammatory cytokines, increased generation of cytokines in uremia, or an adverse effect of inflammation on renal function.

TL;DR: This study indicates that the original Charlson index is a valid tool to assess comorbidity and predict survival in patients with end-stage renal disease, however, the modified ESRD com orbidity index had slightly better performance characteristics in this population.

TL;DR: Pain is a significant problem in more than 50% of HD patients and is not being effectively managed, and the development of effective pain management strategies is necessary to improve the quality of life for dialysis patients.

TL;DR: There are significant needs in both basic and clinical research in the pathogenesis, natural history, prevention, and therapy for hepatitis C in patients with renal disease, particularly among patients with end-stage renal disease and renal transplants.

TL;DR: Treatment of both traditional and uremia-related risk factors should be initiated in the earlier stages of CKD, and additional clinical trials with a goal to reduce CVD are urgently needed in CKD.

TL;DR: In this paper, the relation between body weight and fat distribution and microalbuminuria and elevated or diminished filtration in 7,676 subjects without diabetes was studied, where the total population was divided into six groups according to body weight (overweight is defined as body mass index [BMI] > 25 and ≤ 30 kg/m 2 ; obesity, as BMI > 30 kg /m 2 ) and fat distributions.

TL;DR: The incidence of diagnosed CKD is common, especially in the elderly, and is greater in more deprived areas, and the prognosis is poor, with CVD prominent.

TL;DR: This property supports the notion that abundant THP excretion in urine is promoted in the host by selective pressure to obtain an efficient defense against urinary tract infections caused by uropathogenic bacteria.

TL;DR: Type of initial hemodialysis access was associated with 1-year mortality in the US Medicare dialysis population and Mortality risks were fistulae, grafts, and catheters.

TL;DR: It is shown that treatment with atorvastatin in addition to a regimen with ACE inhibitors or ARBs may reduce proteinuria and the rate of progression of kidney disease in patients with chronic kidney disease, proteinuria, and hypercholesterolemia.

TL;DR: Sedentary behavior is associated with an increased risk for mortality among dialysis patients similar in magnitude to that of other well-established risk factors, such as a one-point reduction in serum albumin concentration.

TL;DR: This cross-sectional study tested the hypothesis that the Physical Component Summary and Mental Component Summary scales of the MOS SF-36 predict morbidity and mortality rates among dialysis patients and found that PCS and MCS were consistent predictors of hospitalizations and deaths even after adjustment for clinically relevant factors.

TL;DR: Until more accurate methods of estimating GFR in cirrhotic patients are adequately validated, care should be exercised in the management of these patients because of the potential for severely impaired renal function, even in the face of normal serum creatinine concentrations.

TL;DR: Patients with ANCA-related SVV and DAH benefit from prompt initiation of apheresis coupled with aggressive immunosuppressive therapy, and such therapy can be lifesaving with respect to the pulmonary component of this syndrome.

TL;DR: Moderate weight loss in overweight patients with chronic proteinuric nephropathies induces a significant decrease in proteinuria.

TL;DR: The beneficial effect of renal clearance and the absence of an effect of peritoneal clearance in the range of values common in current practice on patient outcome indicate that the 2 components of total solute clearance should not be regarded as equivalent.

TL;DR: Symptoms, especially pain, along with psychosocial and spiritual factors, are important determinants of QOL of patients with ESRD and their association with other QOL indices in larger and more diverse patient populations is investigated.

TL;DR: The existence of elements of MICS as indicated by a high MIS and increased levels of proinflammatory cytokines such as IL-6 as well as decreased nutritional values such as low serum concentrations of total cholesterol, prealbumin, and TIBC correlates with EPO hyporesponsiveness in MHD patients.

TL;DR: While kappa-LC deposition was more frequently associated with nodular sclerosing glomerulopathy, histological parameters were not predictors of renal/patient prognosis and Dialysis is worth performing in uremic LCDD patients.

TL;DR: Findings highlight the important role of PKC-MAPK pathway activation in mediating the development and progression of diabetic nephropathy.

TL;DR: In this article, the prevalence of depression in patients with end-stage renal disease (ESRD) starting dialysis therapy, identify patient characteristics associated with depression, and determine whether patients with serious depressive symptoms were receiving treatment.

TL;DR: In this paper, a 4.4-year mortality follow-up of 2,089 men and women without diabetes and treated hypertension, randomly selected from the population-based Nord-Trondelag Health Study (1995 to 1997; n=65,258), was conducted.