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Showing papers in "American Journal of Kidney Diseases in 2007"




Journal ArticleDOI
TL;DR: There was a significant dose-dependent increase in risk of proteinuria and hypertension in patients with cancer who received bevacizumab.

576 citations


Journal ArticleDOI
TL;DR: Uric acid levels are associated strongly with prevalent CKD, and greater uric acid levels had a significant, but much weaker, association with progression of kidney disease.

355 citations


Journal ArticleDOI
TL;DR: Current evidence regarding the associations of blood pressure with proteinuria, the rationale for currently recommended blood pressure goals, and the use of various classes of antihypertensive agents in proteinuric patients is provided.

336 citations


Journal ArticleDOI
TL;DR: GFR estimates using the IDMS MDRD Study equation with the JSN-CKDI coefficient or the new JSN (JSN)KDI equation are more accurate than the IDM (MDRD) Study equation in hospitalized Japanese patients with eGFR less than 60 mL/min/1.73 m(2).

326 citations


Journal ArticleDOI
TL;DR: Application of CKD testing in national and international screening and surveillance programs could improve public health related to CKD and understanding the strengths and limitations of CKd testing is critical for appropriate implementation of these recommendations.

317 citations


Journal ArticleDOI
TL;DR: The magnitude of differences in serum creatinine measurements in NHANES III and 1999-2000 would result in large differences in estimates of kidney function, but no correction is needed for NHANes 2001-2002 or 2003-2004.

285 citations


Journal ArticleDOI
TL;DR: A stepwise increase in the prevalence of albuminuria was observed with decreasing quartiles of vitamin D concentration, and it is unclear whether vitamin D therapy prevents or improves markers of kidney and cardiovascular disease.

268 citations


Journal ArticleDOI
TL;DR: The presence of AAC is significantly associated with both all-cause and cardiovascular mortality in hemodialysis patients, suggesting that careful attention should be given to the presence of the AAC in a simple radiograph of the lateral abdomen as a prognostic indicator.

261 citations


Journal ArticleDOI
TL;DR: The finding that age is a key predictor of CKD, with an odds ratio of 13.95 for the group aged 75-plus years compared with the group younger than 20 years, provides a reasonable explanation for the subsequent epidemic of ESRD in Taiwan.

Journal ArticleDOI
TL;DR: It is shown for the first time that aggressive neointimal hyperplasia is present in venous segment specimens from patients with early AVF failure, and future therapies will need to target this pathogenetic pathway.

Journal ArticleDOI
TL;DR: In this paper, the authors assessed the prevalence of hypernatremia and its impact on mortality and ICU length of stay (LOS) in a 35-month observation period.

Journal ArticleDOI
TL;DR: An sVLPD was effective and safe when postponing dialysis treatment in elderly patients without diabetes in 1-year mortality assessed by using intention-to-treat and per-protocol analysis.

Journal ArticleDOI
TL;DR: In women with renal insufficiency, the presence of both GFR less than 40 mL/min/1.73 m(2) and proteinuria with protein greater than 1 g/d before conception predicts poor maternal and fetal outcomes.

Journal ArticleDOI
TL;DR: It is suggested that fenoldopam reduces the need for renal replacement and mortality in patients with acute kidney injury and a large, multicenter, appropriately powered trial will need to be performed to confirm these results.

Journal ArticleDOI
TL;DR: Short-term mortality and acute decreases in renal function are associated through a graded relationship such that even mild changes in serum creatinine levels portend worse outcome in a variety of clinical settings and patient-types.

Journal ArticleDOI
TL;DR: Calibration improves the performance of the MDRD Study equation and improved the percentage of estimates within 30% of measured GFR from 80% to 83% and varied across studies.

Journal ArticleDOI
TL;DR: Lower BMI is associated with greater mortality in patients with CKD not yet on dialysis therapy, and adjustment for case-mix and surrogate markers of malnutrition and inflammation attenuated, but did not reverse, this relationship.

Journal ArticleDOI
TL;DR: Data confirm the close association between mixedCryoglobulinemia and HCV infection and between glomerulonephritis and type II cryoglobulin and survival profiles are better than previously reported in the literature.

Journal ArticleDOI
TL;DR: There was a dose-dependent increase in risk of proteinuria and hypertension in patients with cancer who received targeted therapies, and few patients with glomerulonephritis or thrombotic microangiopathy secondary to treatment were reported.

Journal ArticleDOI
TL;DR: Mortality among patients on dialysis therapy after primary graft failure increases significantly relative to mortality among patients still awaiting primary kidney transplantation, and the mechanism of the increased risk and strategies to decrease mortality are urgently needed.


Journal ArticleDOI
TL;DR: Low- and full-intensity anticoagulation use in HD patients is associated with a significant bleeding risk, which has to be balanced against any potential benefit of therapy when prescribing warfarin to HD patients.

Journal ArticleDOI
TL;DR: Results show that ergocalciferol administration has a favorable effect on PTH levels if therapy results in an increase in 25-hydroxyvitamin D levels; this effect is more evident in patients with CKD stage 3.

Journal ArticleDOI
TL;DR: Renal damage progression in patients with IgA nephropathy was associated with microscopic hematuria at clinical onset, increased serum creatinine level, increased proteinuria, and grading of histological lesions, which could help identify individual high-risk patients and stratify patients enrolled in randomized clinical trials into homogeneous groups.

Journal ArticleDOI
TL;DR: The history of the clinical and political developments that occurred during the 13 years between these 2 dates and that led to dialysis as the authors know it today in this country are described.

Journal ArticleDOI
TL;DR: It is proposed that the national vascular access initiative be revised to have a dual goal of Fistula First and "Catheters Last," and a systematic refocus on interventions that not only increase fistulas, but help avoid extended catheter use.

Journal ArticleDOI
TL;DR: The purpose of this review is to highlight the importance of this neglected topic by providing an overview of recent epidemiological studies, outcomes data, proposed pathophysiological mechanisms, and emerging treatment options.

Journal ArticleDOI
TL;DR: A meta-analysis of cross-sectional observational studies suggests that BMD is lower in patients with stage 5 CKD who have fractures, and fractures may be prevented by treatments that preserve BMD.