Showing papers in "American Journal of Kidney Diseases in 2011"

TL;DR: Allan J. Collins, MD, Robert N. Foley, MB, Charles Herzog,MD, Blanche Chavers, MDs, David Gilbertson, PhD, Areef Ishani, Md, MS, Bertram Kasiske, MD and Jiannong Liu, PhD.

TL;DR: The nature and extent of TDF-associated kidneyoxicity in the HIV-infected population, potential underlying mechanisms of toxicity in the proximal tubule, and risk factors for developing tubular dysfunction are discussed and suggested strategies to monitor patients on TDF therapy are suggested.

TL;DR: Higher 25(OH)D levels are associated with significantly improved survival in patients with CKD and may be limited by heterogeneity, unconsidered confounders, and the observational design of the studies.

TL;DR: Serum CysC appears to be a good biomarker in the prediction of AKI, whereas urinary CysCs excretion has only moderate diagnostic value.

TL;DR: IAH should be considered as a potential cause of acute kidney injury in critically ill patients and its role in other conditions, such as hepatorenal syndrome, remains to be elucidated.

TL;DR: A Western dietary pattern is associated with a significantly increased odds of microalbuminuria and rapid kidney function decrease, whereas a DASH-style dietary pattern may be protective against rapid eGFR decline.

TL;DR: The CKD-EPI equation without ethnic adjustment for estimating GFR in multiethnic Asian patients with CKD is more accurate than the MDRD Study equation throughout the GFR range, with improved bias and root mean square error.

TL;DR: Serum albumin predicts all-cause, cardiovascular, and infection-related mortality in both peritoneal dialysis patients and HD patients, but the threshold at which risk of death increases varies by dialysis modality, and this difference should be considered by agencies or organizations that set quality standards.

TL;DR: The re-expression of previously reported equations to estimate GFR from Scys for use with Scys values traceable to the new IRMM CRM is reported on.

TL;DR: Plasma exchange may decrease the composite end point of end-stage renal disease or death in patients with renal vasculitis, and additional trials are required given the limited data available.

TL;DR: There is an emerging HD dose-effect in Australia and New Zealand, with lower mortality risks associated with some of the more intensive HD regimens in these countries.

TL;DR: For patients with CKD, this Kidney Knowledge Survey (KiKS) is reliable and valid and identifies areas of and risk factors for poor kidney knowledge.

TL;DR: A graded relationship between severity of CKD and CAC independent of traditional risk factors is showed and support recent guidelines that state that if vascular calcification is present, it should be considered as a complementary component to be included in the decision making required for individualizing CKD treatment.

TL;DR: Administrative database analyses have utility, but must be conducted and interpreted judiciously to avoid bias arising from poor code validity.

TL;DR: A dipstick test result <1+ or less than trace has a high negative predictive value in the general community setting, with minimal risk of a missed diagnosis of macroalbuminuria.

TL;DR: In conjunction withprednisone, induction therapy with tacrolimus is at least as efficacious as intravenous cyclophosphamide and prednisone in producing complete remission of lupus nephritis and has a more favorable safety profile.

TL;DR: Compared with DEXA, multifrequency BIA appears to be a robust tool for measuring and monitoring total-body fat and lean body mass in hemodialysis patients; however, there is less agreement in bone mineral content assessment between the 2 methods.

TL;DR: It is hypothesized that the dialysis procedure itself may have important implications for SCD, and recognition that hemodialysis is associated with both ventricular arrhythmias and dynamic electrocardiographic changes, may show changes that are modifiable by alterations to dialysis prescription.

TL;DR: In this article, the authors explored the interplay among vascular calcification promoters, inhibitors, and substrate that affect phosphorus handling leading to the progression of calcification in individuals with chronic kidney disease.

TL;DR: The findings have unveiled an unexpected link between aging and phosphate, and patients with chronic kidney disease (CKD), patients with CKD have high serum FGF-23 levels with decreased klotho expression in the kidney and parathyroid, rendering F GF-23 and Klotho as potential biomarkers and therapeutic targets for CKD.

TL;DR: The findings suggest the need for interventional studies to test the effects of preventing and treating metabolic syndrome on the risk of kidney stone development.

TL;DR: Attending an options class predialysis was associated with more frequent selection of home dialysis, fewer tunneled HD catheters, and lower mortality risk during the first 90 days of dialysis therapy.

TL;DR: Early nephrologist involvement in patients with AKI may reduce the risk of a further decrease in kidney function and a larger randomized trial is needed to confirm the findings.

TL;DR: In conclusion, hypertension control affects both patient and long-term transplant survival, and its best management requires careful analysis of causes and close monitoring of therapies.

TL;DR: Red blood cell survival in hemodialysis and peritoneal dialysis patients compared with healthy persons is determined and decreased RBC survival contributes to chronic kidney disease-related anemia, although the reduction is less than previously reported.

TL;DR: The CKD-EPI equation reclassifies people at lower risk of CKD and death into higher eGFR categories, suggesting more accurate categorization.

TL;DR: Two-thirds of peritoneal dialysis patients had moderate to severe cognitive impairment, enough to interfere with safely self-administering dialysis and adhering to complex medication regimens, similar to hemodialysis patients.

TL;DR: Measurement of troponin T and NT-pro-BNP may improve the identification of patients with CKD who are likely to require renal replacement therapy, supporting a link between cardiac injury and the development of ESRD.

TL;DR: Basic patient characteristics, comorbid conditions, and laboratory variables can predict 3-year mortality in incident dialysis patients with sufficient accuracy and Identification of subgroups of patients according to mortality risk can guide future research and subsequently target treatment decisions in individual patients.

TL;DR: This review article details how several impediments to Kidney paired donation have been overcome to the benefit of ever greater numbers of patients.