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Showing papers in "American Journal of Obstetrics and Gynecology in 1987"


Journal ArticleDOI
TL;DR: The use of cocaine during pregnancy was associated with lower gestational age at delivery, an increase in preterm labor and delivery, lower birth weights, and delivery of small for Gestational age infants.

338 citations


Journal ArticleDOI
TL;DR: It is suggested that during this period the intervillous space is bathed by an acellular fluid that could be plasma filtered by the trophoblastic shell and its endovascular cone and the physiology of early pregnancy must be reconsidered.

311 citations



Journal ArticleDOI
TL;DR: A hypothesis is formulated suggesting that endometriosis is associated with an increased influx of macrophage that are allowed to undergo further maturation-activation and the resultant population of large macrophages may contribute to the maintenance of the disease or associated infertility.

280 citations


Journal ArticleDOI
TL;DR: Noncompliance, stemming from side effects or the problem of forgetting to take medications, can be improved through the use of the transdermal estrogen formulation, and any problems with unscheduled bleeding or hyperplasia can be circumvented through the addition of progestogens.

270 citations


Journal ArticleDOI
TL;DR: It is concluded that the four-chamber view may be a useful screen for the presence of congenital heart disease and should be included as a part of all routine obstetric ultrasound examinations.

246 citations


Journal ArticleDOI
TL;DR: In this paper, multiple colposcopic biopsy specimens were collected from 160 women, with sampling of principal cervical and vulvar lesions as well as secondary areas of either minor acetowhitening or normal epitheluim.

246 citations


Journal ArticleDOI
TL;DR: It is concluded that the umbilical artery flow velocity waveform systolic/diastolic ratio measures the reflection coefficient at the peripheral vascular bed (the "resistance vessels") of the placenta.

234 citations


Journal ArticleDOI
TL;DR: First-trimester pregnancy hormones were measured in the serum of 35 women with hyperemesis and 35 control women and results are consistent with the hypothesis that elevated estrogen levels are responsible for excessive vomiting in pregnancy.

228 citations


Journal ArticleDOI
TL;DR: Previous estrogen users who stopped estrogen after age 65 years lost bone more rapidly than women of similar age who had never taken estrogen, so early and continued hormone replacement for life is recommended.

215 citations


Journal ArticleDOI
TL;DR: A prospective study of 270 pregnant women with endocervical C. trachomatis found no statistically significant differences between cases and controls for any of these variables, but in the subset of women with recent or invasive chlamydial infection, preterm delivery occurred in 13/67 IgM-positive versus 8/99 IgM -negative cases.

Journal ArticleDOI
TL;DR: Pulmonary edema is infrequent in severe preeclampptic-eclampsia without associated medical, surgical and obstetric complications, but the occurrence of pulmonary edema in such patients is associated with high maternal and perinatal mortality and morbidity.

Journal ArticleDOI
TL;DR: It is concluded that percutaneous estradiol is effective as preventive therapy of postmenopausal bone loss and that addition of progesterone does not influence bone or calcium metabolism.


Journal ArticleDOI
TL;DR: Comparison of curvilinear regression of foot length versus gestational age demonstrated a strong correlation with an R2 value of 0.981; 95% confidence intervals at each week compared favorably with both biparietal diameter and femur length data.

Journal ArticleDOI
TL;DR: It is concluded that, if left untreated, one abnormal value on an oral glucose tolerance test is strongly associated with adverse perinatal outcome.

Journal ArticleDOI
TL;DR: It is suggested that to completely avoid alcohol-related anatomic abnormalities, advice to discontinue drinking or at least to reduce it to a minimal level before conception is clinically appropriate.

Journal ArticleDOI
TL;DR: Pregnancy outcomes were more favorable in the exercise groups, particularly the high-exercise group, and patients reported positive subjective responses to the conditioning program.

Journal ArticleDOI
TL;DR: Observations are compatible with the participation of prostaglandins in the mechanisms of onset of preterm labor associated with intra-amniotic infection.

Journal ArticleDOI
TL;DR: It is suggested that abnormal bacterial colonization of the genital tract may lead to an increase in arachidonic acid metabolism in amnion cells with a increase in prostaglandin E2 production and the consequent initiation of preterm labor.

Journal ArticleDOI
TL;DR: The benefits associated with a trial of labor in the patient with a prior cesarean birth far outweigh the risks and the policy of "once a cesAREan section, always a cESarean section" should be abandoned.

Journal ArticleDOI
TL;DR: Between 1971 and 1985, a total of 325 cases of cervical cancer, Stages IB to IIB, in which operation was performed were evaluated with a view toward prognostic factors and survival rates.

Journal ArticleDOI
TL;DR: One hundred forty-four pregnancies that occurred in 74 patients with congenital heart disease at the Toronto General Hospital between 1975 and 1986 were reviewed and the major benefits of corrective cardiac surgery were in the cyanotic group.

Journal ArticleDOI
TL;DR: It is concluded that in the group of pregnancies delivering neonates greater than or equal to 4000 gm, the occurrence of shoulder dystocia cannot be predicted from clinical characteristics or labor abnormalities, and that the occurrence is not evidence of medical malpractice.

Journal ArticleDOI
TL;DR: The biparietal diameter/femur length ratio may prove superior to current Down syndrome screening methods and, as a third independent variable, may significantly enhance the sensitivity and specificity of combined maternal age/maternal serum alpha-fetoprotein screening modalities.

Journal ArticleDOI
TL;DR: Current prematurity prevention methods are most likely to prevent low birth weight births related to idiopathic premature labor, and the relative success of such programs in reducing the rate of lowBirth weight births is likely to depend on the characteristics of the patient population to which the programs are directed.

Journal ArticleDOI
TL;DR: Current research is aimed at finding the estrogen/progestogen formulations that induce the least changes in the coagulation system and other physiologic processes, and the new low-dose formulations should reduce the risk of vascular thrombotic complications.

Journal ArticleDOI
TL;DR: In this paper, the authors used laparoscopic ovarian cautery to induce ovulation in women with polycystic ovarian disease (POMD) who failed to ovulate with clomiphene citrate and human chorionic gonadotropin.

Journal ArticleDOI
TL;DR: Of 74 women previously treated for anorexia nervosa or bulimia, 15 had conceived 23 pregnancies when assessed at follow-up, and women in whom eating disorders were in remission at conception had greater maternal weight gain and babies with higher birth weights and 5-minute Apgar scores.

Journal ArticleDOI
TL;DR: Ten sera, all from patients with primary habitual abortion, showed high anticardiolipin antibody values, which could be explained at least in part by an activation of complement by the classical pathway.