Showing papers in "Analytica Chimica Acta in 2002"
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TL;DR: A review of the current directions in electrochemical DNA biosensors can be found in this article, where the authors discuss recent strategies and future prospects for electrical detection of DNA hybridization.
508 citations
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TL;DR: Current advances in the development of nanocomposite and mesostructured materials suggest that major improvements in bioimmobilisation are on the horizon, and should result in substantial improvements inBioanalytical devices over the next decade.
470 citations
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TL;DR: In this article, the authors validated the determination of the content of Cd, Cu, Pb and Zn using two digestion protocols: a microwave-assisted total digestion and an aqua regia extraction procedure based on the International Organization for Standardisation (ISO) 11466 method.
389 citations
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TL;DR: A glassy carbon electrode was modified with electropolymerized films of isonicotinic acid in pH 5.6 phosphate buffer solution (PBS) by cyclic voltammetry (CV) as mentioned in this paper.
386 citations
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TL;DR: In this paper, it was shown that low concentrations of trenbolone and melengestrol acetate are very mobile in agricultural soils and have a high affinity to the organic fraction of the immobile phase leading to a high retardation within soil materials.
323 citations
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TL;DR: In this article, the influence of controlled oxygenation on the color and phenolic composition of red wine was studied by UV-VIS spectrophotometry, liquid chromatography coupled to diode array detection (DAD) and electrospray ionisation mass spectrometry, and thiolysis.
287 citations
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TL;DR: In this paper, a new concept of the subset selection with K-means is introduced, which is a new subset selection method based on density based spatial clustering of applications with noise (DBSCAN).
268 citations
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TL;DR: During the last few years, control within the European Union for illegal growth promoters in cattle and pigs revealed only a limited number of positives, however, analysis of illegal preparations showed that steroids, often (esters of) natural hormones, and -agonists are still used.
253 citations
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TL;DR: An electrochemical DNA biosensor based on the recognition of single stranded DNA by hybridization detection with immobilized complementary DNA oligonucleotides is presented and the interaction of MB with inosine substituted probes was investigated.
233 citations
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TL;DR: This review will discuss both single target detection and microarray applications with a focus on gene expression and pathogenic microorganism (PM) detection.
229 citations
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TL;DR: For mixtures of compound, toxicities were additive in only 33% of the cases and 21% of mixtures were less toxic than expected based on the sum of concentrations of toxicants (antagonistic effect).
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TL;DR: Three acetylcholinesterase screen-printed biosensors designed for the detection of pesticides are evaluated and exhibited a storage stability of over 6 months when the enzyme was encapsulated in a polymer film.
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TL;DR: Two techniques for alignment of profiles, namely dynamic time Warping (DTW) and correlation optimized warping (COW) were tested and compared and the attention was focused on chromatographic and spectroscopic profiles.
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TL;DR: In this article, the concept of multicommutation is reviewed in order to permit a proper evaluation of the characteristics and potentialities of related flow systems, to assist methodological implementation and to discuss similarities with other existing strategies.
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TL;DR: Gas chromatography (GC) has been an indispensable analytical technique ever since the first exciting steps in the application of fatty acid determinations in oilseed plant breeding, biosynthesis and human metabolism as mentioned in this paper.
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TL;DR: It is demonstrated that the variables selected by the genetic algorithm are consistent with expert knowledge and a convincing application that the algorithm can select correct variables in an automated fashion.
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TL;DR: In this paper, a novel strategy for the implementation of flow-based analytical procedures using several micropumps is proposed, where the pumps are switched individually or in combination, in order to create a pulsed flowing stream through the analytical path, and are the only active devices acting simultaneously as liquid propelling units, sample insertion ports and commuting elements.
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TL;DR: A colorimetric protein phosphatase inhibition (PPI) assay, a commercial enzyme-linked immunosorbent assay (ELISA) test and different HPLC methods using UV detection were compared for the detection of cyanobacterial hepatotoxins, microcystins (MCYST) and nodularin this article.
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TL;DR: In this paper, an electrochemical detection method for analyzing sequence-specific DNA using gold nanoparticle DNA probes and subsequent signal amplification step by silver enhancement is described, which relies on the electrostatic adsorption of target oligonucleotides onto the sensing surface of the glassy carbon electrode (GCE) and its hybridization.
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TL;DR: The suitability of the HPAEC method was clearly shown by analyzing a series of steady state S. cerevisiae samples from a carbon limited aerobic chemostat culture and validation of the glucose-6-phosphosphate LC–MS–MS analysis results with enzymatic analysis showed an excellent agreement between the two methods.
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TL;DR: In this paper, terbium ion fluorescence was used as a post-column detection system for the simultaneous determination of catecholamines norepinephrine (NE), epinephrine (E) and dopamine (DA).
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TL;DR: In this article, the interactions between terazosin and bovine serum albumin (BSA) were studied by spectrofluorimetry, and the binding constants of BSA were measured at different temperatures.
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TL;DR: In this paper, a mixed-thiol modified gold electrode (MUA:MU/cyt c electrode) was used for a superoxide detection system based on the spontaneous dismutation of KO2 and a new calibration method was established.
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TL;DR: In this article, the authors describe the simultaneous determination of six resveratrol derivatives in wines by liquid chromatography (LC) with fluorescence detection, and the levels of pallidol, the symmetrical dimer of reserveratrol, are reported for the first time.
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TL;DR: Gas-liquid chromatography (GLC) has been widely used in the field of analytical analysis of short-chain fatty acids and has been used in many applications, such as volatile lipids and related materials as mentioned in this paper.
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TL;DR: In this article, the authors reviewed the legislative framework controlling the use of veterinary medicines and zootechnical food additives in the EU, and examples of interventions to minimise contamination are given.
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TL;DR: In this paper, the authors developed a method for the pre-treatment and determination of antimony, arsenic, cadmium, chromium, lead, mercury and selenium in human hair by inductively coupled plasma mass spectrometry (ICP-MS).
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TL;DR: In this paper, chemical modification of poly(methyl methacrylate) (PMMA), and poly(carbonate) (PC) surfaces for applications in microfluidic systems was described.
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TL;DR: A review of the current knowledge of fatty acid analysis can be found in this paper, with an emphasis on the analysis of fatty acids in microorganisms in relation to microbial taxonomy, chemotaxonomy, and clinical practice.
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TL;DR: In this paper, Radial basis function networks (RBFN) with regularized forward selection to control the model complexity were used for non-parametric regression, resulting in a RMSEP of 0.25%.