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Showing papers in "Analytica Chimica Acta in 2004"


Journal ArticleDOI
TL;DR: In this paper, the authors provide an in-depth look at the state-of-the-art in integrated microfludic devices for a broad range of application areas from on-chip DNA analysis, immunoassays and cytometry to advances in integrated detection technologies for and miniaturized fuel processing devices.

738 citations


Journal ArticleDOI
TL;DR: This paper presents an ant colony optimization methodology for optimally clustering N objects into K clusters which employs distributed agents which mimic the way real ants find a shortest path from their nest to food source and back.

496 citations


Journal ArticleDOI
TL;DR: In this paper, a microfluidic lab-on-a-chip (LoC) platform for in vitro measurement of glucose for clinical diagnostic applications is presented, where droplets act as solution-phase reaction chambers and are manipulated using the electrowetting effect.

466 citations


Journal ArticleDOI
TL;DR: In this paper, the conditions required to form nanoliter-sized droplets (plugs) of viscous aqueous reagents in flows of inuniscible carrier fluid within microfluidic channels were characterized.

388 citations


Journal ArticleDOI
TL;DR: In this article, the authors compared three extraction methods: 0.01 µm-l − 1 CaCl 2 (The Netherlands), 0.1 µm − 1 NaNO 3 (Switzerland), and 1 µm−l −1 NH 4 NO 3 (Germany).

352 citations


Journal ArticleDOI
TL;DR: In this article, a method for assessing the occurrence of trace amounts of 12 representative estrogenic compounds in sewage and surface waters was developed, which consists in solid phase extraction (SPE) performed with OASIS cartridges followed by liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).

348 citations


Journal ArticleDOI
TL;DR: In this paper, a reagentless uric acid (UA) biosensor based on uricase immobilized on ZnO nanorods was developed, which showed a high thermal stability up to 85°C and an electrocatalytic activity to the oxidation of urea without the presence of an electron mediator.

331 citations


Journal ArticleDOI
TL;DR: In this article, the taste and mouth-feel properties of three different types of tannin-like polyphenolic compounds, representative of some of the TPC compounds found in red wines, were determined using descriptive sensory analysis.

320 citations


Journal ArticleDOI
TL;DR: In this paper, the authors used NIR spectroscopy to simultaneously predict the concentrations of malvidin-3-glucoside (M3G), pigmented polymers (PP) and tannins (T) in red wine.

312 citations


Journal ArticleDOI
TL;DR: In this article, current ideologies concerning the sources of DOC, how it is formed and utilized, and what determines the quality of DOC are examined, and developments in methods of analysis including the isolation and characterization of this fraction are reviewed.

298 citations


Journal ArticleDOI
TL;DR: In this article, the electrochemical oxidation of the (+)-catechin was investigated, over a wide range of conditions, using cyclic, differential and square wave voltammetry.

Journal ArticleDOI
TL;DR: In this paper, the authors evaluated the antioxidant activity of wine samples by different analytical methods, including oxygen radical absorbance capacity (ORAC), 2,2′-azinobis-(3-ethylbenzothiazoline)-6 sulfonic acid (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH).

Journal ArticleDOI
TL;DR: In this paper, Nafion, a perfluorosulfonated polymer, was used to solubilize single-wall carbon nanotubes (SWCNTs) to fabricate electrochemical sensors.

Journal ArticleDOI
TL;DR: In this paper, an optimization of the colorimetric method of Johnson and Pilson (1972) to accurately measure As concentrations in the <0.03 −5.3mol L −1 (<2 −400 gL −1 ) range in groundwater containing 2 −30mol l −1 dissolved phosphate was reported.

Journal ArticleDOI
TL;DR: In this article, the extraction of 75 elements by TODGA from nitric acid to n-dodecane was investigated and discussed concerning distribution ratios (D) of metal ions and their ionic radii.

Journal ArticleDOI
TL;DR: A solid phase microextraction (SPME) and gas chromatography (GC) based analytical method for the simultaneous separation and determination of 16 polycyclic aromatic hydrocarbons (PAHs) from aqueous samples has been developed, based on the sorption of target analytes on a selectively sorptive fibre and subsequent desorption of analytes directly into GC-MS.

Journal ArticleDOI
TL;DR: In this paper, a simple and sensitive method for the determination of hydroxyl radicals generated in advanced oxidation processes is described, which employed the reaction between hydroxyn radicals and dimethyl sulfoxide (DMSO) to generate quantitatively formaldehyde, which then reacted with 2,4-dinitrophenylhydrazine (DNPH) to form the corresponding hydrazone (HCHO-DNPH).

Journal ArticleDOI
TL;DR: In this paper, a polymer obtained by imprinting with Ni(II) ion as a ion-imprinted solid phase extraction (SPE) sorbent was synthesized and polymerized with cross-linking ethyleneglycoldimethacrylate to obtain [poly(EGDMA-MAH/Ni(II))].

Journal ArticleDOI
TL;DR: In this paper, the iron-cobalt complexes of 2,3,7,8,12,13,17,18-octakis(benzylthio)-5,10,15,20-tetraazaporphyrin (OBTAP) were synthesized and incorporated into PVC matrix as ionophores to fabricate anion selective membrane electrodes that exhibit selective potentiometric response to azide and nitrite ions, respectively.

Journal ArticleDOI
TL;DR: In this paper, a changeable size moving window partial least squares (CSMWPLS) and a searching combination moving window part-least-squares (SCMWPLs) are proposed to search for an optimized spectral interval and an optimized combination of spectral regions from informative regions obtained by a previously proposed spectral interval selection method.

Journal ArticleDOI
TL;DR: In this article, a micro flow cytometer which is capable of counting and sorting cells or particles is presented, which employs electrokinetic forces rather than the more conventional hydrodynamic forces technique for flow focusing and sample switching.

Journal ArticleDOI
TL;DR: In this article, a carbon nanotube (CNT) modified glassy carbon electrodes exhibiting a strong and stable electrocatalytic response towards sulfide are described. But the CNT-coated electrodes thus allow highly sensitive, low potential (+0.1 ǫ) amperometric sensing.

Journal ArticleDOI
TL;DR: A photodegradation study of triclosan, a commonly used antimicrobial agent, was carried out in order to investigate the formation of dibenzodichlorodioxin as a byproduct of photodegrad in various environmental matrices and under different conditions.

Journal ArticleDOI
TL;DR: In this article, an electronic tongue based on amperometric detection in a flow injection system (FIA) and a commercial electronic nose have been used to characterize and classify four types of Barbera wines having different denominations of origin and produced in northern Italy in enclosed geographical areas.

Journal ArticleDOI
TL;DR: In this paper, a poly(methyl methacrylate)/poly(decyl methacelate) (MMA/DMA) copolymer as membrane matrix was solvent-cast on a layer of poly( n -octyl)thiophene (POT) deposited on Au as internal contact.

Journal ArticleDOI
TL;DR: The work explores the evolution of the silhouette values computed from the clusters built by using k-means when non-informative variables are added to the original data set in both a literature data set as well as some simulated data in higher dimension.

Journal ArticleDOI
TL;DR: In this paper, a comparative study of imprinted polymers with a similar composition were synthesised by bulk, suspension, emulsion, two-step swelling and precipitation polymerization, and their ability to rebind propranolol under identical analytical conditions was assessed from organic and aqueous solutions by radioligand binding.

Journal ArticleDOI
TL;DR: In this article, the assessment of hazard from selenium (Se) and mercury (Hg) contaminants in the food chain based on their potential bioaccessibility and on estimate of their actual content in fish is reported under an in vitro model.

Journal ArticleDOI
TL;DR: In this paper, a liquid chromatographic-tandem mass spectrometric (LCMS-MS) method for most of those penicillins and cephalosporins for which EU maximum residue limits (MRL) were set in Council regulation (EEC) 2377/90 was developed and validated in bovine muscle, kidney and milk.

Journal ArticleDOI
TL;DR: In this paper, Baga native variety from the Portuguese Bairrada Appellation, harvest 2000, were submitted to a liquid-liquid continuous extraction with dichloromethane and analysis by gas chromatography-mass spectrometry (GC-MS).