Showing papers in "Analytica Chimica Acta in 2012"

TL;DR: These approaches have exhibited an excellent analytical performance with high sensitivities due to the strong LSPR and excellent selectivity strategically driven by the interaction analyte-NPs surroundings involving mainly electrostatic and hydrogen bond interactions as well as donor-acceptor chemical reactions, among others.

TL;DR: ZnO nanostructures have shown the binding of biomolecules in desired orientations with improved conformation and high biological activity, resulting in enhanced sensing characteristics, and compatibility with complementary metal oxide semiconductor technology for constructing integrated circuits makes ZnO Nanostructure suitable candidate for future small integrated biosensor devices.

TL;DR: The Cu-graphene sheets electrode allows highly selective and sensitive, stable and fast amperometric sensing of glucose, which is promising for the development of non-enzymatic glucose sensor.

TL;DR: This manuscript aims to review the various NGM techniques and devices and the challenges and future trends in NGM.

TL;DR: The topic of LC-MS-based global metabolic profiling is reviewed and the current challenges, limitations and opportunities of the current methodology are highlighted.

TL;DR: This critical review describes the basic fabrication principles, the configuration designs of SPEs and the hybrid analytical techniques based on SPEs, including the determination of organic compounds, heavy metals and gas pollutants over the past 3 years.

TL;DR: The developments in data acquisition and multivariate analysis of NMR-based metabolomics data are described, with particular emphasis on the metabolomics of Cerebrospinal Fluid and biomarker discovery in Multiple Sclerosis.

TL;DR: An overview at the current status of ionic liquid-modified materials applied in solid-phase extraction, liquid and gas chromatography and capillary electrochromatography with reference to recent applications and the potential of Ionic liquids in the modification of capillary inner wall in capillary electrophoresis is demonstrated.

TL;DR: A new ultrasound-assisted extraction method was developed for the determination of phenolic compounds present in grapes, which produced similar or higher recoveries for these three parameters; however a much shorter extraction time was needed.

TL;DR: This review focuses on the developments and analytical applications of fluorescent nanoparticles in chemical and biological sensing within the intracellular environment, and points out the great potential of fluorescent NPs for fluorescence lifetime imaging microscopy (FLIM).

TL;DR: The use of CNTs as solid-phase extraction and microextraction sorbents, as part of membranes as well as their use in chromatography and electrophoresis will be discussed and commented.

TL;DR: The results clearly indicated that NIR hyperspectral imaging technique has the potential as a fast and non-invasive method for predicting quality attributes of lamb meat.

TL;DR: Under the optimum extraction conditions, the AALLME method showed low limits of detection and quantification and some aqueous samples were successfully analyzed using the proposed method and three analytes, DIBP, DNBP and DEHP, were determined in them at ng mL(-1) level.

TL;DR: In this paper, a portable sensor consisting of flame-deposited and in situ annealed, Si-doped epsilon-WO(3) nanostructured films was developed.

TL;DR: A new analytical protocol by TIMS is presented that aims at improving analytical efficiency and cutting down experimental cost, and the analytical results obtained for these standard rocks show a good agreement with reported values, indicating the effectiveness of the proposed method.

TL;DR: A comprehensive review about the fabrication of SiNW biosensors and their applications in disease diagnostics discusses the detection of important biomarkers related to diseases including cancer, cardiovascular diseases, and infectious diseases.

TL;DR: Comparative studies showed that graphene is superior to other adsorbents including C18 silica, graphitic carbon, and single- and multi-walled carbon nanotubes for the extraction of Pb and reveals the great potential of graphene as an excellent sorbent material in analytical processes.

TL;DR: The outstanding film forming ability of RGO-MWNTs hybrid materials endowed the modified electrode enhanced stability and the fabricated sensor was applied for the simultaneous determination of HQ, CC, PC and NO(2)(-) in the river water sample.

TL;DR: Hyperspectral imaging technique was investigated for objective determination of pork quality attributes and indicated that this technique is a potential tool for rapid assessment of Pork quality.

TL;DR: A method using reversed-phase ultra high performance liquid chromatography (UPLC) coupled with electrospray ionization tandem mass spectrometry (ESI/MSMS) to simultaneously quantify 28 urinary VOC metabolites as biomarkers of exposure is developed.

TL;DR: In this review, insights are provided into the analytical potential of quantum dots focusing on prospects of their utilisation in automated flow-based and flow-related approaches and the future outlook of QDs applications in chemical analysis.

TL;DR: Various reasons for its scarce implementation in routine analytical laboratories despite its high analytical potential are identified, as well as the probably main "niche" for successfully practical developments is suggested.

TL;DR: Nitrogen-doped graphene sheets and chitosan were used to prepare electrochemical BPA sensor, which exhibits a sensitive response to BPA and was successfully employed to determine BPA in water samples with satisfactory results.

TL;DR: The present work describes the construction and application of a simple, low cost and sensitive microfluidic paper-based device with electrochemical detection for the detection of paracetamol and 4-aminophenol.

TL;DR: This article provides a review of how functionally modified gold colloids are applied in the detection of a broad range of threat agents, including radioactive substances, explosive compounds, chemical warfare agents, biotoxins, and biothreat pathogens through any of the four sensory means mentioned previously.

TL;DR: Polydimethylsiloxane is gaining importance in the manufacturing of lab-on-a-chip devices, which have revolutionized bio-analysis and the field of analytical chemistry.

TL;DR: The development of algorithms that possess the advantages of RJMCMC methods and are also efficient and easy to follow for selecting disease-associated genes is required.

TL;DR: Photopatterning appears thereby as one of the most suitable methods for patterning MIP at the micro and nano scale, directly on the transducer surface, significantly simplifies the integration of MIP for sensor applications.

TL;DR: A sensitive luminescent bioassay for the simultaneous detection of Salmonella Typhimurium and Staphylococcus aureus was developed using aptamer-conjugated magnetic nanoparticles for both recognition and concentration elements and using upconversion nanoparticles (UCNPs) as highly sensitive dual-color labels.

TL;DR: This review summarizes the use of microextraction methods in food flavor compounds analysis based on papers published in the last 5years, and discusses the potential of micro Extraction techniques in this field.