scispace - formally typeset
Search or ask a question

Showing papers in "Analytica Chimica Acta in 2017"


Journal ArticleDOI
TL;DR: The aim of this review was to introduce conventional and recently-developed extraction techniques, with emphasis on the use of DESs as potential extractants for various bioactive compounds, such as phenolic acid, flavonoids, tanshinone, keratin, tocols, terpenoids, carrageenans, xanthones, isoflavones, α-mangostin, genistin, apigenin, and others.

326 citations


Journal ArticleDOI
TL;DR: A critical review of recent developments and challenges of colorimetric detection on microfluidic paper-based analytical devices (μPADs) are presented, and thoughts and insights towards future perspectives in the area to improve the use ofcolorimetric readouts in conjunction with μPADS are presented.

276 citations


Journal ArticleDOI
TL;DR: It is shown that convolutional neural networks can be efficiently used to classify vibrational spectroscopic data and identify important spectral regions and a new CNN based method is developed, which outperforms standard classification algorithms used in chemometrics and achieves better performance even on preprocessed test data.

258 citations


Journal ArticleDOI
TL;DR: A step-by-step tutorial on development of SRM/MRM protein assay intended for researchers without prior experience in proteomics is presented.

252 citations


Journal ArticleDOI
TL;DR: Application of main techniques widely used for preparation of a variety of coating materials of SPME, including sol-gel technique, electrochemical and electrospinning methods as well as the available commercial coatings, were presented and advantages and limitations of each technique were investigated.

234 citations


Journal ArticleDOI
TL;DR: The analytical performance of MIP materials in sample preparation is commented as function of the complexity of the matrix, and it is compared to that exhibited by (commercial) aspecific and/or immunosorbent phases.

233 citations


Journal ArticleDOI
TL;DR: Attention is paid to the increasing role of the HILIC mode in various two-dimensional LC techniques and the related mobile phase compatibility problems, and the impact of dual HilIC-reversed phase (RP) mechanism on a possible increase of the applications of some polar columns.

210 citations


Journal ArticleDOI
TL;DR: There is a lack in the application of nanomaterials for on-line analysis procedures, most probably due to some intrinsic properties of nanmaterials such as spontaneous agglomeration.

192 citations


Journal ArticleDOI
TL;DR: In this work, an "on-off" fluorescence phosphorus/nitrogen dual-doped CQDs (PNCQDs) probe was developed for the determination of Cr(VI) based on inner filter effect (IFE) and the as-constructed fluorescent sensing system was successfully applied to the analyses of AA in fresh fruits and in commercial fruit juices with satisfactory results.

187 citations


Journal ArticleDOI
TL;DR: A novel paper-based electrochemical biosensor using an anthraquinone-labeled pyrrolidinyl peptide nucleic acid probe (AQ-PNA) probe and graphene-polyaniline modified electrode to detect human papillomavirus (HPV) type 16 is promising for the screening and monitoring of the amount of HPV-DNA type 16 to identify the primary stages of cervical cancer.

164 citations


Journal ArticleDOI
TL;DR: The magnetically susceptible resultant MIPs (MMIPs) allowed a simple and fast elution of the template molecules from MMIPs, are easily and faster collected without filtration, centrifugation or other complex operations and are also faster assembled and removed from the electrode surface by simply using an external magnetic field.

Journal ArticleDOI
TL;DR: Key aspects related to the development, optimisation and validation of suitable class models for the characterisation of food products are critically analysed and discussed.

Journal ArticleDOI
TL;DR: An extensive review of the latest advances in continuous flow microfluidic rare cell separation and processing with each cell's specific characteristics and separation challenges as a point of view is provided.

Journal ArticleDOI
TL;DR: The first example of a paper-based screen-printed biosensor for the detection of ethanol in beer samples is reported, highlighting suitability towards its utilization in sensor development, and offers an affordable and sustainable tool for food quality control.

Journal ArticleDOI
TL;DR: This review includes nearly all the studies on the fabrication and applications of graphene-peptide based biosensors recently, which will promote the future developments of graphene in biomedical detection and environmental analysis.

Journal ArticleDOI
TL;DR: The present review critically summarizes and discusses the progress made since 2010 in the development and application of new electrodes for the analysis of metals and metalloids.

Journal ArticleDOI
TL;DR: The largest number of applications of molecular recognition mechanisms was observed for molecularly imprinted polymer monoliths as a consequence of the simplicity of this approach when compared to the use of immunosorbents or aptamers.

Journal ArticleDOI
Man He1, Lijin Huang1, Bingshan Zhao1, Beibei Chen1, Bin Hu1 
TL;DR: An overview of the use of advanced functional materials (AFMs) in SPE for ICP-MS determination of trace elements and their species in the past decade is presented, including nanometer-sized materials, porous materials, ion imprinting polymers, restricted access materials and magnetic materials.

Journal ArticleDOI
TL;DR: The present review provides a general overview of the analytical chemistry applications of PIMs reported in the literature to date and illustrates their versatility for solving challenging chemical analysis problems.

Journal ArticleDOI
TL;DR: This review critically evaluates microfluidic sample preparation platforms and separation methods for biomarker analysis reported in the last two years and key advances in device operation and ability to process different sample matrices in a variety of device materials are highlighted.

Journal ArticleDOI
TL;DR: This review covers the progress between 2010 and 2015 in the field of technologies enabling biosensor applications in environmental analysis, including i) printing technology, ii) nanomaterial technology, iii)nanomotors, iv) biomimetic design, and (v) microfluidics.

Journal ArticleDOI
Biao Gu1, Liyan Huang1, Wei Su1, Xiaoli Duan1, Haitao Li1, Shouzhuo Yao1 
TL;DR: The benzothiazole-based fluorescent probe BT showed ratiometric fluorescent response to Hg2+ and fluorescence quenching behavior to Cu2+, which induces naked-eye fluorescent color changes from green to blue and colorless, respectively.

Journal ArticleDOI
TL;DR: The chelating resin is shown to have a high affinity for all analyzed elements, with recoveries between 83 and 100% for all elements, except Mn, and showed higher recoveries for Ni, Cd, Pb, Co and Mn in direct comparison to an alternative resin (NOBIAS Chelate-PA1).

Journal ArticleDOI
TL;DR: The dual immunosensor was applied to the simultaneous determination of IL-1β and TNF-α in human serum spiked at clinically relevant concentration levels and in real saliva samples and exhibits excellent reproducibility of the measurements, storage stability of the anti-IL-Phe-DWCNTs/SPCE and anti-TNF-Pleasanton conjugates, and selectivity as well as negligible cross-talking.

Journal ArticleDOI
TL;DR: The as-prepared Fe3O4@PEI-RGO, integrating the superiority of PEI and RGO, showed higher extraction efficiency for polar acidic herbicides and the adsorption mechanism was investigated as well.

Journal ArticleDOI
TL;DR: This review compares the microfluidic platforms for dielectrophoretic manipulation of microbials and their coupling to various detection modalities, including immuno-capture, impedance measurement, Raman spectroscopy and nucleic acid amplification methods, as well as for phenotypic assessment of microbial viability and antibiotic susceptibility.

Journal ArticleDOI
TL;DR: It was showed that OM composition depends primarily on soil and sediment characteristics, and two sequential extraction protocols, progressing from polar to non-polar solvents, were found to provide the highest number and diversity of organic compounds extracted from the soil and sediments.

Journal ArticleDOI
TL;DR: This review presents an overview of the most recent advances in obtaining RAMs based on silica, polymers, carbon nanotubes, (activated) carbon, and solvents, as well as their applications in biological sample preparation.

Journal ArticleDOI
TL;DR: 2D and 3D microfluidic paper-based analytical devices (μPADs) for monitoring glucose, total protein, and nitrite in blood serum and artificial urine are fabricated and presented an excellent analytical performance for all analytes.

Journal ArticleDOI
TL;DR: The sequential normalization strategy was demonstrated to significantly improve patient stratification by decreasing the unwanted variability and thus enhancing data quality.