Annals of African Medicine 

About: Annals of African Medicine is an academic journal published by Medknow. The journal publishes majorly in the area(s): Medicine & Population. It has an ISSN identifier of 1596-3519. Over the lifetime, 1002 publications have been published receiving 12039 citations.

Inflammation and cancer.

Abstract: Inflammation is often associated with the development and progression of cancer. The cells responsible for cancer-associated inflammation are genetically stable and thus are not subjected to rapid emergence of drug resistance; therefore, the targeting of inflammation represents an attractive strategy both for cancer prevention and for cancer therapy. Tumor-extrinsic inflammation is caused by many factors, including bacterial and viral infections, autoimmune diseases, obesity, tobacco smoking, asbestos exposure, and excessive alcohol consumption, all of which increase cancer risk and stimulate malignant progression. In contrast, cancer-intrinsic or cancer-elicited inflammation can be triggered by cancer-initiating mutations and can contribute to malignant progression through the recruitment and activation of inflammatory cells. Both extrinsic and intrinsic inflammations can result in immunosuppression, thereby providing a preferred background for tumor development. The current review provides a link between inflammation and cancer development.

Treatment of pterygium.

Abstract: The treatment of ocular pterygium has been subjected to the development and application of various new strategies in the last few years. The worrisome problem of recurrence seems to have been significantly reduced with the newer methods of treatment. The field is however, still evolving. This review sets out to examine the various newer approaches to treating pterygium and in spite of the recent developments, to highlight the remaining challenges thereby suggesting the possible direction of future research. Also, to suggest treatment options for Ophthalmologists working in environments with limited resources. A library search and Internet search of PubMed and Google was conducted in 2010. Search terms included "pterygium in combination with surgery", "radiotherapy", "chemotherapy", "graft", and "recurrence." Abstracts were reviewed and relevant articles especially those published from the year 2000 to date were given more attention and when possible, reviewed in full. The relevant references in such articles were also reviewed. In conclusion, excision and adjunctive treatment with mitomycin C or conjunctival autograft is the most acceptable and most popular mode of treating both primary and recurrent pterygium. Outcomes seem to have been further improved with adjuvant combination therapy and the introduction of newer approaches to treatment.

Factors influencing the pattern of self-medication in an adult Nigerian population.

Abstract: Background: Despite the growing research interest in self-medication, little information has been available about its major determinants especially in developing countries. This informed the conduct of this study to determine the major factors that influence the pattern of self medication in a population of market women in Ifako-Ijaiye area of Lagos, Nigeria. Methods: Interviewer administered pretested semistructured questionnaire was used to collect data from 205 market women selected by multistage sampling technique. Results: The patent medicine dealers were the commonest source of information on medications (31.4%) and where they were obtained (52.2%). The exceptions were the educated (62.5%) respondents who obtained theirs from hospitals and pharmacies. Trade and generic names (61.1%) were common means of drug recognition especially among the educated respondents (P Keywords : Factors; pattern; self-medication; market women; Nigeria Annals of African Medicine Vol. 7 (3) 2008: pp. 120-127

Urbanization, cities, and health: The challenges to Nigeria - A review.

Abstract: The Nigerian society is rapidly becoming urban as a result of a multitude of push and pull factors. This has generated urban health crises among city dwellers notably the urban poor. A systematic search of published literature in English was conducted between 1960 and 2015. Published peer review journals, abstracts, Gray literature (technical reports, government documents, reports, etc.), inaugural lectures, and internet articles were reviewed. Manual search of reference lists of selected articles were checked for further relevant studies. The review showed that the pace of urbanization is unprecedented with cities such as Lagos having annual urban growth rate of 5.8%. Urbanization in Nigeria is mainly demographically driven without commensurate socioeconomic dividends and benefits to the urban environment. This has created urban health crises of inadequate water safe supply, squalor and shanty settlements, sanitation, solid waste management, double burden of diseases and inefficient, congested, and risky transport system. In conclusion, when managed carefully, urbanization could reduce hardship and human suffering; on the other hand, it could also increase poverty and squalor. Some laws need to be amended to change the status of poor urban settlements. Urban health development requires intersectoral approach with political will and urban renewal program to make our urban societies sustainable that promote healthy living.

Determinants of place of delivery among women in a semi-urban settlement in Zaria, northern Nigeria

Abstract: Background/Objective: Majority of the maternal deaths that occur especially in developing countries are avoidable or preventable. Studies have shown that the health, reproductive behaviour and socio economic status of women are among the important determinants of maternal mortality. This study was aimed at assessing the role of some health, socio-economic and demographic factors in determining the place of delivery among women in a semi-urban settlement in Zaria, north-western Nigeria. Method: The study design was a cross sectional descriptive study conducted in Sabuwar Unguwa, Magume district Zaria Local Government Area Kaduna State Nigeria in June, 2003. A total of 496 women who had delivered at least once were interviewed using a pre-tested interviewer administered questionnaire. Results: The study revealed both high rates of home deliveries and deliveries not supervised by skilled attendants of 70% and 78% respectively. Mother's educational level, husband's occupation and age at first pregnancy were the main determinants of place of delivery. Statistically significant associations between non- formal education and home delivery, (X 2 = 6.7 df = 1 P 2 =18.7 df = 1 P 2 = 0.59 df = 1 P>0.05). Conclusion: Low maternal education, unemployment among fathers, first pregnancies at less than 18 years of age increase the likelihood of home delivery in Sabuwar Unguwa, Magume district of Zaria. Girl child education, income generating activities and training of TBAs could reduce the high rate of home deliveries and its consequences in the study area. Keywords: Delivery, place, determinants Annals of African Medicine Vol. 5(2) 2006: 68-72