Showing papers in "Biochimica et Biophysica Acta in 1978"

TL;DR: These vesicles prove to be excellently suited for transport studies, as suggested by the measurements of D-glucose transport, and the mode of choline transport across the brush border membrane was investigated.

TL;DR: One of the major proteins of the outer membrane of Escherichia coli, the matrix protein (porin), has been isolated by detergent solubilisation and the findings are consistent with the assumption that the protein forms large aqueous channels in the membrane.

TL;DR: Abnormal synthesis of fibronectin and other matrix components and abnormal interactions with the tissue matrix may account for several phenotypic characteristics of transformed cultutred cells and for some of the malignant behavior of neoplastic cells in vivo.

TL;DR: A modification of two similar procedures further increases the sensitivity, simplicity, and stability of the protein-dye binding assay over those of other commonly used assays for protein.

TL;DR: The polymorphic phase behavior of aqueous dispersions of phosphatidylethanolamines isolated from human erythrocytes, hen egg yolk and Escherichia coli have been investigated employing 31P NMR techniques as mentioned in this paper.

TL;DR: Although cholesterol has a marked effect on hydrocarbon chain organization, it was found that, within the resolution limits of the data, the phosphatidylcholine head group conformation is unchanged by the addition of cholesterol to the bilayer.

TL;DR: It is proposed that the bilayer structure of lipids in biomembranes may be in dynamic equilibrium with other available phases and a mechanism of “flip-flop” phenomena in biological membranes is suggested.

TL;DR: It is suggested that a release of constraints imposed by spectrin enables phosphatidylserine and phosph atidylethanolamine to move from the inner to the outer lipid layer of the erythrocyte membrane and that spectrin stabilizes the orientation of these phospholipids to the inner surface of the membrane.

TL;DR: Pyranine is shown to be a convenient and sensitive probe for reporting pH values, pHi, at the interior of anionic and at the outer surface of cationic liposomes, and in the presence of sodium acetate proton equilibration is promptly established.

TL;DR: In non-infected young pea seedlings, no lysopine dehydrogenase activity was detected and enzyme activities as low as 0.2 micrometerol octopine or nopaline per h per g fresh weight tumour tissue can still be detected.

TL;DR: The exchange protein did not appear to influence cholesterol esterification in lipoproteins by phosphatidylcholine cholesterol acyl-transferase, and the latter had no effect on the transfer of low density lipoprotein cholesteryl esters to high density lipiprotein.

TL;DR: A simple, rapid radiochemical assay for prostacyclin synthesis has been used to characterize the enzyme in arterial walls which converts prostaglandin endoperoxides to prostacyClin, which displays a broad pH optimum, and catalyses a rapid conversion of saturating concentrations of the endoperoxide.

TL;DR: It was concluded that proline forms aggregates by stepwise stacking and hydrophobic interaction of the pyrrolidine ring, and the proposed multimer contans aHydrophobic backbone and hydphilic groups on the surface, exposed to water.

TL;DR: The nature of Ca2+-induced changes in bilayers containing negatively charged phospholipids is strongly dependent on the character of the polar headgroup of the negatively chargedospholipid involved.

TL;DR: It is concluded that inorganic phosphate, 3-phosphoglycerate, dihydroxyacetone phosphate and glyceraldehyde phosphate are transported by the same carrier, which has been nominated phosphate translocator.

TL;DR: Comparison of the effects of amino acids with those of glucose and palmitate indicated that amino acids were not acting by providing substrates for energy metabolism, and the age and or nitritional state of the animal may influence the response of skeletal muscle to altered amino acid levels.

TL;DR: Massive release of entrapped 125I-labeled albumin from the liposome during incubation with plasma suggests that the observed release of phosphatidylcholine from theliposomes has a highly destructive influence on the Liposomal structure.

TL;DR: The results indicate that the plasma membrane and mitochondrial ATPases are distinct enzymes, in spite of the fact that they may play related roles in H+ transport across their respective membranes.

TL;DR: It is postulated that melittin causes a wedge effect in membranes, which under physiological conditions, in water,melittin is in extended conformation, which is enhanced in aqueous ethanol, however in 'membrane-like' conditions it is essentially alpha-helical.