Showing papers in "Biochimica et Biophysica Acta in 1988"

TL;DR: The cytochrome aa3 spectrum in vivo from the brains of rats after replacing the blood with a fluorocarbon substitute is obtained and an algorithm for calculating the changes in oxygenated and deoxygenated haemoglobin and oxygenated cy tochrome a a3 in tissue from changes in near IR absorption is constructed.

TL;DR: The weight of the evidence suggests strongly that there is a direct interaction between the sugars and lipids in the dry state and that these effects may be important in the survival of intact cells and organisms such as seeds in the absence of water.

TL;DR: The mechanism of reversible electric breakdown of lipid membranes is studied and hydrophilic pores of an effective radius of 0.6 up to more than 1 nm are formed, which account for the membrane conductivity increase observed.

TL;DR: A fairly coherent picture of the design and function of many short ‘sorting signals’ attached either permanently or transiently to the protein is beginning to emerge.

TL;DR: With inadequate selenium intake there was a priority supply of the element to the brain, the reproductive and the endocrine organs, and at a molecular level to Se-containing proteins other than glutathione peroxidase.

TL;DR: Cl in ica l and exper imen ta l cons ide ra t ions of organ-speci f ic metas tas i s .

TL;DR: Using DCMU addition and light-saturation pulses, chlorophyll fluorescence quenching by isolated barley protoplasts has been examined upon illumination with different light intensities.

TL;DR: The spectrum of the protein after the second stage of thermal denaturation is the same as that after the first stage of alkaline denaturation (at pH 11), suggesting a common denaturation intermediate, which probably represents a crossover point in a complex potential hypersurface.

TL;DR: The divergent influence of acetylator phenotype on the incidence of tumors in different organ sites suggests an important role for extrahepatic acetyltransferases, and further characterization of them in human and animal tissues is needed.

TL;DR: The reactions leading to synthesis of the sulfated oligosaccharides are examined to determine which steps are hormone specific, and differences in sulfation and sialylation of LH, FSH and TSH may also play a role in the regulation of hormone bioactivity.

TL;DR: The stoichiometry of c Cecropin killing of bacteria suggests that amounts of cecropin sufficient to form a monolayer strongly modify the bacterial membrane.

TL;DR: Tetrahydrolipstatin is a specific lipase inhibitor derived from lipstatin, a lipid produced by Streptomyces toxytricini that inhibits human gastric lipase, carboxyl ester lipase (cholesterol esterase) of pancreatic origin and the closely related bile-salt-stimulated lipase of human milk.

TL;DR: Type II cells maintained in culture acquire immunoreactivity to monoclonal antibodies, demonstrating that type II cells in vitro have the capacity to develop a characteristic associated with type I cells in situ.

TL;DR: Biochemical studies with strains of Escherichia coli that are amplified for the products of the three fumarase genes have shown that there are two distinct classes of fumarases, and it is suggested that the Class I enzymes may belong to a wider family of iron-dependent carboxylic acid hydro-lyases that includes maleate dehydratase and aconitase.

TL;DR: The results demonstrate the presence of a phospholipase A2 in the macrophage cell line, RAW 264.7, that preferentially hydrolyzes arachidonoyl-containingospholipid substrates and shows apparent specificity for arachidonic acid at the sn-2 position.

TL;DR: A systemic formalism is developed that shows how the results for absolute specific volumes of multilamellar lipid dispersions may be combined with results from diffraction studies to obtain quantitative characterizations of the average structure of fully hydrated lipid bilayers.

TL;DR: It is proposed that increased lipid peroxidation may contribute to the toxic actions of Pb2+ in humans.

TL;DR: It was concluded that cells that were capable of modifying LDL produced superoxide or a substance that could be converted to superoxide in the medium, and that superoxide was an important, though possibly indirect, mediator of the modification of LDL by cells.

TL;DR: Evidence is provided for significant lipid peroxidative damage in the erythrocyte membrane during aging in vivo and by measuring lipid extract fluorescence, by lipid thin-layer chromatography for the presence of adduct of phosphatidylserine, PE and malondialdehyde and by thiobarbituric acid-reactivity.

TL;DR: In this paper, the authors explored the origins of the unidirectionality of electron transfer between the excited singlet state of the bacteriochlorophyll dimer and the bacteriopheophytin (H) along the L protein subunit.

TL;DR: Phospholipid flip-flop was strongly dependent on headgroup composition with a smaller dependence on acyl chain length, and transfer rates for the PE derivatives were 5-to 7-fold slower than the rates observed for PC, with the exception of PE.

TL;DR: Investigation of the interplay between lipoic acid and glutathione in microsomal Fe2+ (10 microM)/ascorbate (0.2 mM)-induced lipid peroxidation shows that this effect can be ascribed completely to reduction of GSSG to GSH by reduced lipoIC acid, which may provide a rationale for the therapeutic effectiveness of lipoics acid.