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Showing papers in "Biochimica et Biophysica Acta in 1989"


Journal ArticleDOI
TL;DR: In this article, the quantum yield of non-cyclic electron transport was found to be directly proportional to the product of the photochemical fluorescence quenching (qQ) and the efficiency of excitation capture by open Photosystem II (PS II) reaction centres (Fv/Fm).

7,821 citations


Journal ArticleDOI
TL;DR: In this paper, the extinction coefficients for chlorophylls a and b in diethylether (Smith, J.H. and Benitez, A.V., eds.), used in this paper as primary standards, were verified by magnesium determination using atomic absorbance spectrophotometry.

5,326 citations


Journal ArticleDOI
TL;DR: In this paper, the comportement energetique des bicouches lipidiques avec description des methodes permettant de mesurer les forces entre molecules lipidiques.

1,074 citations


Journal ArticleDOI

970 citations



Journal ArticleDOI
TL;DR: Most mitochondrial proteins are synthesized as precursors on cytosolic polysomes and are subsequently imported into mitochondria as discussed by the authors, where they are stored on the outer membrane of the mitochondria.

775 citations



Journal ArticleDOI
TL;DR: Etude de la synthese des groupements fonctionnels glycosyl-phosphatidylinositol se liant aux extremites C terminales des proteines procaryotique ou eucaryotiques, permettant leur determination et leur identification.

485 citations


Journal ArticleDOI
TL;DR: The identification of both topoisomersase I and II as the specific targets of cancer chemotherapeutic drugs now provides a rational basis for the development of topoisomerase I poisons for possible clinical use and may lead to the identification of new therapies for treating cancer.

471 citations


Journal ArticleDOI
TL;DR: The ability to achieve significant prolongation in circulation times of liposomes makes possible a number of therapeutic applications ofliposomes which, until now, have not been achievable.

458 citations


Journal ArticleDOI
TL;DR: The methods by which the intra-mitochondrial volume is measured both in vitro and in situ are described, the mechanisms thought to regulate the mitochondrial volume are summarised and evidence that changes in mitochondrial volume may be important in the responses of a variety of tissues to hormones and other stimuli is provided.

Journal ArticleDOI
TL;DR: Tumor stroma formation results from the interaction of tumor cells and their products with the host and certain of its normal defense mechanisms, particularly the clotting and fibrinolytic systems, and serves to regulate the influx of macrophages, and perhaps other inflammatory cells.

Journal ArticleDOI
TL;DR: Examination of the sites phosphorylated on acetyl-CoA carboxylase, hormone-sensitive lipase, glycogen synthase and phosphorylase kinase suggests a consensus recognition sequence in which the serine residueosphorylated by the AMP-activated protein kinase has a hydrophobic residue on the N-terminal side.

Journal ArticleDOI
TL;DR: The developmental profiles of the four major brain gangliosides were examined in human frontal lobe covering the period from 10 fetal weeks to 80 years of age, demonstrating more dynamic changes of theganglioside patterns during development than noted in previous studies.

Journal ArticleDOI
Vann Bennett1
TL;DR: Property of known and potential constituent proteins of the spectrin-actin junction, regulation of their interactions, the role of junction proteins in erythrocyte membrane dysfunction, and to consider aspects of assembly of the junctions are considered.

Journal ArticleDOI
TL;DR: While sphingosine has appeared to be a relatively potent and specific inhibitor of protein kinase C in the systems studied, recent findings with the epidermal growth factor receptor indicate that it may serve as a pleotrophic modulator of cell functions.

Journal ArticleDOI
TL;DR: The key research problems of micellar enzymology and its relation to enzyme membranology are discussed.

Journal ArticleDOI
TL;DR: In this paper, the authors have shown that the non-photochemical quench relaxes with complex kinetics, revealing at least three components with half-times of about 1 min (fast), 5 min (middle), and hours (slow).

Journal ArticleDOI
TL;DR: The binding of neomycin to PIP2 is investigated by making electrophoretic mobility measurements with multilamellar bilayer vesicles and surface potential measurements with monolayers and results are consistent with a hypothesis that most of the PIP1 in the inner leaflet of these plasma membranes is not accessible to neomyin because it is associated with proteins.

Journal ArticleDOI
TL;DR: Native fully hydrated fibrin gels formed at different fibr inogen and thrombin concentrations and at different ionic strengths were studied by confocal laser 3D microscopy, liquid permeation and turbidometric analyses of the gels, showing decreased gel porosity and fiber mass/length ratio and diameter.

Journal ArticleDOI
TL;DR: In this paper, it was shown that whereas gel-state lipids cannot be extruded at convenient pressures, systems incubated at temperatures above the gel-to-liquid-crystalline transition (T c ) can be readily extruded through filters with pore sizes ranging from 30 nm to 200 nm to produce homogeneously sized systems.

Journal ArticleDOI
TL;DR: Dans cette revue sont definies, quantifiees et commentees les principales donnees cinetiques concernant la catalyse interfaciale et l'activation interfaciales par la phospholipase A 2.

Journal ArticleDOI
TL;DR: Although the overall transfection activity of the liposome containing the quaternary ammonium detergent is somewhat lower than that of the Lipofectin, it may serve as an inexpensive and convenient alternative.

Journal ArticleDOI
TL;DR: Three lines of investigations are in progress which aim at the structural analysis of a given modification, elucidating its various biological functions and at an understanding of the biosynthetic event of the modification.

Journal ArticleDOI
TL;DR: In order to study the effect of the nucleus on dielectric behavior of the whole cell, permittivity and conductivity of mouse lymphocytes and erythrocytes were measured over a frequency range from 0.1 to 250 MHz.

Journal ArticleDOI
TL;DR: The key finding was that LDL receptors clustered in coated pits, structures that had been described by Roth and Porter 10 years earlier, and thus established receptor-mediated endocytosis as a distinct mechanism for the transport of macromolecules across the plasma membrane.


Journal ArticleDOI
TL;DR: Mature 125I-labelled Mn-SOD, isolated from rabbit liver, was not imported in vitro into mitochondria, indicating that the energy-dependent uptake of Mn-sOD by liver mitochondria was specific for the Mn- SOD precursor.

Journal ArticleDOI
TL;DR: N-terminal and internal sequences derived from the rat tumor-secreted phosphoprotein indicate that it is identical to rat osteopontin, a bone protein with an Arg-Gly-Asp cell-binding sequence, which is likely a human homolog of human bone sialoprotein I.

Journal ArticleDOI
TL;DR: It is demonstrated that induction of indoleamine 2,3-dioxygenase is a common feature of interferon-gamma action, that the extent of this induction is influenced by extracellular L-tryptophan concentrations and that indoleamines 2, 3-Dioxy genase is the only enzyme in the formation of 3-hydroxyanthranilic acid from tryptophan which is regulated by interferons-Gamma.