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Showing papers in "Biochimica et Biophysica Acta in 1990"


Journal ArticleDOI
TL;DR: Synthese des mecanismes de photoprotection chez les vegetaux, en reponse a un eclairement energetique; implication des carotenoides, en particulier la zeaxanthine, a la dissipation d'energie, en relation avec le cycle des xanthophylles.

1,555 citations


Journal ArticleDOI
TL;DR: To facilitate the reading of this review, the various subtopics of this rapidly expanding field are presented, each of which is organized as a self-contained sub-chapter that can be read independently of the others.

1,081 citations


Journal ArticleDOI
TL;DR: The chiral stationary phase transitions of non-lamellar phase transitions are studied to show the role of chiral reprograming in the evolution of phase-by-phase chiral phase transitions.

1,031 citations



Journal ArticleDOI
TL;DR: It is suggested that HDL may play a protective role in atherogenesis by preventing the generation of an oxidatively modified LDL.

827 citations


Journal ArticleDOI
TL;DR: Despite the structural complexity of integral membrane proteins, it is interesting that in some respects their study be more straightforward, lacking as they do the elusive properties of melittin which limit the possibility of defining their interaction with membranes in terms of a single conformation, location, orientation and association state within the membrane.

813 citations


Journal ArticleDOI
TL;DR: The regula t ion of gene express ion in l iving organisms rests main ly upon the recogniT ion of nucleic acid base sequences by pro te ins, but nucleic acids can also p lay a role.

775 citations


Journal ArticleDOI
TL;DR: Mechanisms of H2 activation and electron transfer are proposed to explain the effects of CO binding and the ability of one of the hydrogenases to preferentially catalyze H2 oxidation and H2 production.

718 citations


Journal ArticleDOI
TL;DR: Long circulation time and high retention of the newly developed liposomes open up ways for the future systemic use as such stabilized drug carriers for the therapeutic applications in vivo.

694 citations



Journal ArticleDOI
TL;DR: Monensin, a monovalent ion-selective ionophore, has gained wide-spread acceptance as a tool for studying Golgi apparatus function and for localizing and identifying the molecular pathways of subcellular vesicular traffic involving acid compartments.

Journal ArticleDOI
TL;DR: The present review has summarized many of the recent studies that have just begun to conceptually integrate this expanding array of TGF beta functions into the context of a three-dimensional, multicellular organ or tissue, be it normal or diseased.

Journal ArticleDOI
TL;DR: Fluorescent analogues of two of the diacylglycerol-based cationic amphiphiles examined in this study are shown to be readily degraded after incorporation into CV-1 cells from PE/cationic lipid dispersions.

Journal ArticleDOI
TL;DR: The enzymes of sphingomyelin turnover release ceramide and free sphingosine from endogenous substrates, which may have implications for the participation of a sphingomelin/sphingoine cycle as another 'lipid second messenger' system.

Journal ArticleDOI
TL;DR: Chromosomal protein structure; Chromatin structure; Gene structure; DNA-protein interaction; High Mobility group protein; High mobility group protein.


Journal ArticleDOI
TL;DR: Synthese des Small nuclear Ribo Nucleoproteines (SnRNP) essentielles a l'epissage des premRNA nucleaires: composition, interactions proteine-proteines ou proteines-RNA, structures en microscopie electronique et role au niveau du spliceosome.

Journal ArticleDOI
TL;DR: Analysis of the phospholipid composition of the intact mitochondria and all subfractions showed that the inner membrane was virtually devoid of phosphatidylinositol and -serine, while the outer membrane contained 23% of the total mitochondrial cardiolipin, which did not originate from inner membrane contamination and therefore is a true component of the outer membranes.



Journal ArticleDOI
TL;DR: The present results indicate that scrambling of membrane phospholipids can only occur provided that aminophospholipid translocase is inactive, and support and extend the suggestion made by Sims et al. (1989) that membrane fusion, which is required for shedding to occur, produces transient flip-flop sites for membrane phosphate groups.

Journal ArticleDOI
TL;DR: The in vivo activation of Rubisco was markedly increased in UV-B-treated pea leaves and the underlying mechanisms for these results are discussed.

Journal ArticleDOI
TL;DR: The catalase activity of the enzyme and the protective role of compound III against an H2O2-dependent peroxidase inactivation are both shown to be important.

Journal ArticleDOI
TL;DR: In spinach thylakoids, heat-induced increase of the Chl a fluorescence yield is also differentially sensitive to the addition of DMQ and DCBQ suggesting that this increase is mainly on the 'I' level, and thus heating is suggested to convert active PS II to inactive PS II centers.

Journal ArticleDOI
TL;DR: Not only IL1, but also TNF alpha can exert profound influences on the collagen degradation and repair processes occurring in the pathology of articular cartilage.

Journal ArticleDOI
TL;DR: Quantitative analysis of its importance shows that about 20-30% of the oxygen consumption by resting hepatocytes is used to drive a heat-producing cycle of proton pumping by the respiratory chain and proton leak back to the matrix.

Journal ArticleDOI
TL;DR: This pH gradient-dependent encapsulation technique is extremely versatile, and well characterized liposomal doxorubicin preparations can be generated to exhibit a wide range of properties such as vesicle size, lipid composition, drug-to-lipid ratio and drug release kinetics.

Journal ArticleDOI
TL;DR: Electrostatic interaction energies of the electron carriers with their surroundings in a photosynthetic bacterial reaction center are calculated and are shown to be relatively insensitive to various details of the model, including the charge distribution in P+, the atomic charges used for the amino acid residues, the boundaries of the structural region that is considered microscopically and the treatments of the histidyl ligands of P and of potentially ionizable amino acids.

Journal ArticleDOI
TL;DR: The transport of the orally absorbed cephalosporin, cephalexin, was examined in the human epithelial cell line, Caco-2 that possesses intestinal enterocyte-like properties when cultured to represent a cellular model for future studies of the dipeptide transporter.

Journal ArticleDOI
TL;DR: The cellular uptake of microcystin-LR, a cyclic heptapeptide hepatotoxin from the cyanobacterium Microcystis aeruginosa, was studied by means of a radiolabelled derivative of the toxin, indicating that the uptake is through the multispecific transport system for bile acids.