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Showing papers in "Biochimica et Biophysica Acta in 1997"



Journal ArticleDOI
TL;DR: The electron-transport chains of Escherichia coli are composed of many different dehydrogenases and terminal reductases (or oxidases) which are linked by quinones (ubiquinone, menaquinone and demethylmenaquinone); Quinol:cytochrome c oxido-reductase ('bc1 complex') is not present.

681 citations


Journal ArticleDOI
TL;DR: Iron uptake by mammalian cells is mediated by the binding of serum Tf to the TfR, and recent work has suggested that the short-lived messenger molecule, NO, can affect cellular Fe metabolism via its interaction with IRP1.

676 citations






Journal ArticleDOI
TL;DR: The basic features of the photosystem I complex were discussed in this article. But the basic features were not discussed in this paper, and they were not considered in this article, either.

480 citations


Journal ArticleDOI
TL;DR: Several definable motifs have now been mapped to the linear amino acid sequence of the APC polypeptide, suggesting that inactivation of APC in cancer is likely due to loss of function(s) normally associated with the deleted protein structure.

476 citations


Journal ArticleDOI
TL;DR: The transmembrane form of HB-EGF is a juxtacrine growth and adhesion factor and is uniquely the receptor for diphtheria toxin.

452 citations




Journal ArticleDOI
TL;DR: In this article, the effect of high temperature (above 40°C) on Chlorophyll a fluorescence rise kinetics starting from 40 μs (to 1 s) in pea leaves (Pisum sativum) was examined.

Journal ArticleDOI
TL;DR: Increased lipid peroxidation and decreased antioxidant protection frequently occur, but they are not universal features of aging.


Journal ArticleDOI
TL;DR: Since macrophages constitute the major site of liposome localization after parenteral administration and play an important role in the control of the immune system, cationic liposomes should be used with caution to deliver gene or antisense oligonucleotide to mammalian cells.

Journal ArticleDOI
TL;DR: Electron density calculations suggest that the different reactivities cannot be attributed solely to differences in electron distribution along the polyene chain of the different chromophores, which would alter the susceptibility to free-radical addition to the conjugated double-bond system.

Journal ArticleDOI
TL;DR: The structure of the core catalytic unit of ATP synthase, alpha 3 beta 3 gamma, has been determined by X-ray crystallography, revealing a roughly symmetrical arrangement of alternating alpha and beta subunits around a central cavity in which helical portions of gamma are found.

Journal ArticleDOI
TL;DR: This paper has detailed their discovery, biochemical attributes and substrate specificities and has provided information as to the methodology used to detect and manipulate their activities.

Journal ArticleDOI
TL;DR: Several magainin analogs with different charges (0 to +6) and hydrophobicities are synthesized and systematically studied their interactions with the outer and inner membranes of three species of Gram-negative bacteria, indicating the importance of electrostatic interactions.

Journal ArticleDOI
TL;DR: In this article, the results of a systematic study on liposome variables potentially affecting lymphatic disposition and biodistribution of liposomes after sc injection were reported, showing that the lymphatic uptake from the s.c. injection site of small liposoms (about 0.04 microm) was relatively high (76% of the injected dose (%ID)) as compared to large, non-sized liposOME, which remained almost completely at the site of injection.

Journal ArticleDOI
TL;DR: The concentration of PEG-grafted lipids required for the inhibition of erythrocyte adhesion decreases with increasing molecular weight of the grafted PEG, and the implication on the function of stealth liposomes is discussed.

Journal ArticleDOI
TL;DR: The ability of carotenoids to protect egg-yolk phosphatidylcholine lipids against oxidation by peroxyl radicals generated from azo-initiators was studied and Lycopene was destroyed most rapidly but was least effective as an antioxidant.


Journal ArticleDOI
TL;DR: In this article, the second-order rate constants of the reactions of chlorogenic acid with superoxide and hydroxyl radical with a pulse radiolysis were found to be 1.67 +/- 0.28 and 3.19 x 10(9) M(-1) s(-1), respectively.


Journal ArticleDOI
TL;DR: TEL–PDGF receptor and chronic myelomonocytic leukemia, ALK and lymphoma, RET and multiple endocrine neoplasia type 2, and other mutations.

Journal ArticleDOI
TL;DR: The current under-standing of the biological consequences of FTI treat-ment of normal and transformed cells is summarized, and speculations as to where future researchefforts in these areas might usefully be directed are presented.

Journal ArticleDOI
TL;DR: The deduced three-dimensional structures of cold alpha-amylase, beta-lactamase, lipase and subtilisin have been compared to their mesophilic homologs and it appears that the molecular adaptation resides in a weakening of the intramolecular interactions, and in some cases in an increase of the interaction with the solvent, leading to more flexible molecular edifices capable of performing catalysis at a lower energy cost.