Showing papers in "Biomaterials in 2002"

TL;DR: Analysis of the measured data shows a high correlation between the scaffold porosity and the compressive properties based on a power-law relationship.

TL;DR: Advantages of photopolymerization of hydrogels are presented, the photoinitiators and materials in current use are described and the applications that have been investigated are summarized.

TL;DR: PEG and folic acid modification of magnetite nanoparticles could be used to resist the protein adsorption and thus avoid the particle recognition by macrophage cells, and to facilitate the nanoparticle uptake to specific cancer cells for cancer therapy and diagnosis.

TL;DR: Poly(ethylene glycol) (PEG) hydrogels were investigated as encapsulation matrices for osteoblasts to assess their applicability in promoting bone tissue engineering and a concentration dependence of RGD groups was observed, with increased osteoblast attachment and spreading with higher RGD concentrations.

TL;DR: A theoretical model was developed that allows to predict the erosion mechanism of water insoluble biodegradable polymer matrices and it was shown experimentally that poly(alpha-hydroxy ester) matrices, which are considered classical bulk eroding materials, can also undergo surface erosion.

TL;DR: The results support the conclusion that properly prepared silkworm fiber matrices, aside from providing unique benefits in terms of mechanical properties as well as biocompatibility and slow degradability, can provide suitable biomaterial matrices for the support of adult stem cell differentiation toward ligament lineages.

TL;DR: These techniques include high resolution and high temperature X-ray diffractometry and FTIR spectroscopy show that very small variations of the Ca/P molar ratio of the powder lead to great changes in powder composition and characteristics after thermal treatment.

TL;DR: An image-based homogenization optimization approach is demonstrated that can design scaffold microstructure, scaffold material and regenerate tissueMicrostructure to meet conflicting design requirements and ensure adequate cell/gene delivery can be introduced using a minimum porosity threshold.

TL;DR: The photopolymerization of mixtures of Bis-GMA/TEGDMA, Bis-gMA/UDMA and Bis- GMA/Bis-EMA showed a good linear relationship of degree of conversion with the mole fraction of Bis -GMA and in the case of the first pair also with the Tg of the initial monomer mixture.

TL;DR: A unique, heterogeneous, osteochondral scaffold is developed using the TheriForm three-dimensional printing process, suggesting that these scaffolds have desirable mechanical properties for in vivo applications, including full joint replacement.

TL;DR: For the first time, hydrogel scaffolds with a designed external shape and a well-defined internal pore structure were prepared by this RP process and the versatile application potential of new hydrogels was demonstrated in cell culture.

TL;DR: In this study, several techniques were utilized to investigate the interactions between quaternary ammonium functionalized poly(propylene imine) dendrimers and bacterial membranes to establish the basis for their mode of action.

TL;DR: Intrinsically cell non-adhesive PVA hydrogels were functionalized with the cell-adhesion peptide RGDS and found to support the attachment and spreading of fibroblasts in a dose-dependent manner, and suggest that photopolymerizable PVA Hydrogels are promising for tissue engineering applications.

TL;DR: A new generation of alumina-zirconia nano-composites having a high resistance to crack propagation, and as a consequence may offer the option to improve lifetime and reliability of ceramic joint prostheses.

TL;DR: The mechanical, thermal and swelling properties of the films are very close to those previously obtained for glutaraldehyde crosslinked gelatin, and suggest that genipin, which is by far less cytotoxic, can be considered a valid alternative for crosslinking gelatin biomaterials.

TL;DR: The effects of pinning density and chain length are interrelated, but the key factor is optimization of PEG chain density by use of the CP conditions, provided that a sufficient density of pining sites exists.

TL;DR: In cytotoxicity test using L929 fibroblastic cells, the EDC-cross-linked membranes demonstrated no significant toxicity and in enzymatic degradation test, EDC treated membranes showed significant enhancement of the resistance to collagenase activity in comparison with 0.625% glutaraldehyde treatment.

TL;DR: Preliminary results showed that controlling the overall geometry of the regenerated bone tissue is possible through the internal architectural design of the scaffolds, and the mechanical and the in vivo performance of designed HA implants were characterized.

TL;DR: The chitosan hydrogel due to its accelerating healing ability is considered to become an excellent dressing for wound occlusion and tissue adhesive in urgent hemostasis situations.

TL;DR: It appears that the addition of silver onto implantable medical devices could be beneficial when specific biological properties, such as antibacterial behaviour, are required.

TL;DR: The results of the study demonstrated that the genipin-crosslinked chitosan microspheres have a superior biocompatibility and a slower degradation rate than the glutaraldehyde-cross linked chitOSanmicrospheres, which may be a suitable polymeric carrier for long-acting injectable drug delivery.

TL;DR: The surface properties of anodic oxides formed on commercially pure (c.p.) titanium screw implants as well as to study 'native' oxides on turned c.p. titanium implants are investigated to elucidate the influence of the oxide properties on the biological reaction.

TL;DR: The complicate conformational behavior in the amide I, II and III bands seems to be affected by the cross-linking induced directional arrangement of HAp/COL nanocomposite fibrils.

TL;DR: In this paper, the physicochemical properties of nanoparticles were investigated by using size exclusion chromatography, FT-IR, dynamic light scattering, transmission electron microscope and zeta potential.

TL;DR: QAS-coated silicone rubber shows antimicrobial properties against adhering bacteria, both in vitro and in vivo.

TL;DR: In this paper, the authors used polymer demixing of polystyrene and poly(4-bromostyrene) producing nanometrically high islands, and observed endothelial cell response to the islands.

TL;DR: While not addressing all facets of ISO 10993 testing, the biocompatibility and SEM data indicate few concerns about use of typical MEMS materials in implant applications.

TL;DR: The biocompatibility of chitosan modified by several methods was carefully evaluated at the cellular and protein levels using different physical and biological methods and a basic theory for the modification of biomaterials is provided.

TL;DR: OWLS is presented to demonstrate how monitoring the modification of different metal oxides with polymers and the response of the coated oxides to biofluids help in the design of novel biomaterials and how OWLS is useful for accurate bioaffinity sensing, which is a key issue in the development of new drugs.

TL;DR: Histological and immunohistochemical staining and scanning electron microscopy observation indicated that the osteoblasts attached to and proliferated on the scaffolds, and the cell/scaffold constructs had good biomineralization effect after 3 weeks in culture.