Showing papers in "Biophysical Journal in 1976"

TL;DR: The theoretical basis and some practical guidelines for simple, rigorous analysis of FPR experiments are presented and some model experiments on aqueous solutions of rhodamine 6G are described.

TL;DR: A method based on the Fourier convolution theorem is developed for the analysis of data composed of random noise, plus an unknown constant "base line," plus a sum of (or an integral over a continuous spectrum of) exponential decay functions.

TL;DR: An effective experimental system for the characterization of molecular and structural mobility that incorporates a modified fluorescence microscope geometry and a variety of analytical techniques to measure effective diffusion coefficients ranging over almost six orders of magnitude.

TL;DR: Micropipette measurements of isotropic tension vs. area expansion in pre-swollen single human red cells gave a value of 288 +/- 50 SD dyn/cm for the elastic, area compressibility modulus, which correlates well with data on in vitro, monolayer surface pressure versus area curves at oil-water interfaces.

TL;DR: Assuming that the shape of red blood cells is controlled by the curvature elasticity of the surrounding membrane, theoretical shapes are fit to the contours Evans and co-workers determined by interference microscopy.

TL;DR: In this paper, the anisotropy of the spin-diffusion coefficient Ds of water protons in skeletal muscle has been studied by pulsed NMR methods, and it was shown that there is a large fraction of the cellular water associated with the proteins in such a way that its diffusion coefficient is substantially reduced.

TL;DR: It is concluded that aminopyrimidines may be used as tools to block the potassium conductance in excitable membranes, but only within certain specific voltage and frequency limits.

TL;DR: A general predictive relation for the convection heat transfer from animal forms is developed, and employs a simple, unique characteristic dimension to represent the animal which is the cube root of the animal volume.

TL;DR: Externally applied 3-aminopyridine or 4-AMP, 4-AmP substantially diminished gK+ in the presynaptic terminal of the squid giant synapse without blocking synaptic transmission and provide a simple tool for the study of voltage-dependent calcium conductance changes in this terminal.

TL;DR: Methods of the qualitative theory of differential equations are used to determine the conditions necessary for a system of equations to have an oscillatory solution, and a model satisfying these conditions is shown to preduct many experimental observations of Aplysia abdominal ganglion R15 cell behavior.

TL;DR: Three specimen preparation techniques for electron microscopy were used to investigate the incorporation of the ATPase polypeptide chains in the membranes of fragmented sarcoplasmic reticulum (SR) obtained from rabbit skeletal muscle, and it is proposed that the outer leaflet of the SR membrane is prevalently composed of the enzyme lipoprotein complex, and the inner leaflet is mostly a phospholipid monolayer.

TL;DR: Tests for correlation between spike trains indicate that the responses of auditory nerve fibers to a tone and to silence can be described as statistically independent point processes, which implies that the initiation of spikes in these fibers is governed by localized processes specific for each fiber.

TL;DR: These conclusions account for the observed helical and circular trajectories of sperm, and for the figure eight motion of the tip of the flagellum in the planar case.

TL;DR: A precedure is described by which an artifact in the time-dependent spectra can be eliminated and the data for the generation of time-resolved emission spectra are obtained with a computer-interfaced instrument based on the single-photon counting method.

TL;DR: Analysis of data indicated that the inhibition of DNA synthesis could be explained by replication forks halting at pyrimidine dimers, which is the predicted pattern if DNA synthesis in each replicon continued at its previous rate until a lesion is reached, and then halted.

TL;DR: The potential distribution within the internodal axon of mammalian nerve fibers is derived by applying known node potential waveforms to the ends of an equivalent circuit model of the internode, and the extracellular potential waveform depended on the location of the nodes within the tube.

TL;DR: Frog urinary bladder epithelium has been examined by freeze-fracture electron microscopy of preparations previously fixed by glutaraldehyde either at rest or during antidiuretic challenge and particle clusters were observed, both in the presence and in the absence of water net flow.

TL;DR: The Tunneling transfer of electrons between two sites, appropriate to biological intermolecular electron transfer, contains physical considerations which are not important in the tunneling transfer between two metals.

TL;DR: A mathematical model for the motion of a bacterial population in prescribed attractant or repellent gradients is presented and predictions of the theory are in general agreement with the experiments of Dahlquist et al.

TL;DR: The secondary structures of the histones, H1, H2A, H3, and H4 have been predicted utilizing the predictive scheme of Chou and Fasman and a new set of conformational parameters based on the X-ray data of 29 protein structures.

TL;DR: The yield of fluorescence in Chlorella from a 7 ns pulse of light is found to decrease gradually as a function of the number of hits in the photosynthetic units, which supports the view that this random process is not in the time but in the spatial domain.

TL;DR: The bilayer must be surrounded by a torus of alkane solvent, petroleum jelly, or silicone grease depending upon the details of technique used to form the bilayer.

TL;DR: Results are reported for the quantum efficiency of Chlorella as a function of intensity, but with picosecond excitation, and show a drop of quantum efficiency with intensity in agreement with results of Mauzerall.

TL;DR: The macromolecular structure (protein-protein interaction which may result in the possible exciton interaction of the retinal pi-pi* (NV1) transition moments and protein-lipid interaction) are not significantly altered and the interaction between the apoprotein and retinal seems to be relatively more pronounced than the 13-cis form.

TL;DR: A theory of viscoplasticity formulated by Prager and Hohenemser is developed for a two-dimensional membrane surface and applied to the analysis of the flow of "microtethers" pulled from red blood cells attached to glass substrates.

TL;DR: Pulsed Nd laser experiments in suspensions of the purple membrane of Halobacterium halobium are carried out at room temperature, and a photostationary mixture of bacteriorhodopsin and its red-shifted photoproduct is obtained.

TL;DR: The shape distributions of normal and hardened human and rabbit erythrocytes and platelets were obtained for edge-on orientations of a few hundred freely rotating cells from analyses of microphotographs obtained similarly as by Ponder (1930), with the best model for platelets appearing to be an oblate spheroid.

TL;DR: The recent results of Campillo et al. and Mauzerall on the quenching of the fluorescence of chlorophyll a in Chlorella pyrenoids as a function of the intensity of the laser excitation pulses are rationalized by applying a model invoking singlet-singlet exciton annihilation.