Showing papers in "Biosensors and Bioelectronics in 2015"
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TL;DR: This review outlines some of the advantages and challenges that may accompany a transition from macroscopic to microfluidic cell culture and focuses on decisive factors that distinguish Macroscopic from microfluidity cell culture to encourage a reconsideration of how macroscopy cell culture principles might apply to micro fluidiccell culture.
760 citations
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TL;DR: The new wireless mouthguard biosensor system is able to monitor SUA level in real-time and continuous fashion, and can be readily expanded to an array of sensors for different analytes to enable an attractive wearable monitoring system for diverse health and fitness applications.
439 citations
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TL;DR: This review introduces briefly the recent achievements in electrochemical sensing of heavy metal ions with inorganic, organic and bio-materials modified electrodes, and the unique properties of inorganic nanomaterials, organic small molecules or their polymers, enzymes and nucleic acids for detection ofheavy metal ions are highlighted.
434 citations
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TL;DR: This review provides an overview of the strategies involved in aptamer-based ELASA, a systematic evolution of Ligands by Exponential Enrichment (SELEX) method that can generate a nucleic acid-based probe (aptamer) that possess numerous advantages compared to antibodies.
434 citations
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TL;DR: This review discusses aspects related to the application of different nanomaterials (e.g. gold nanoparticles, carbon nanotubes, quantum dots, up-converting phosphor technologies, and latex beads, between others) in LFBs.
427 citations
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TL;DR: This review gives an introduction to aptamer including the selection process SELEX with its focus on aptamer advantages over antibodies, and depicts LFIA with itsfocus on aptamers opportunities in LFIA over antibodies to provide a general guide for the design of aptamer-based lateral flow biosensing assays.
414 citations
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TL;DR: High attractive electrochemical properties and electrocatalytic activity of these elite nanomaterials have facilitated achievement of enhanced signal amplification needed for the construction of ultrasensitive electrochemical affinity biosensors for detection of glucose, cholesterol, Escherichia coli, influenza virus, cancer, human papillomavirus and amino acids.
312 citations
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TL;DR: It is envisioned that more novel F-CNPs-based nanosensors with more accuracy and robustness will be widely used to assay and remove various metal ions, and there will be more practical applications in coming years.
298 citations
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TL;DR: In this work, a novel fluorescence resonance energy transfer (FRET) biosensor based on graphene quantum dots (GQDs) and gold nanoparticles (AuNPs) pairs was developed for Staphylococcus aureus specific gene sequence detection.
296 citations
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TL;DR: TiO2-Ti3C2 nanocomposite could be a promising matrix for the fabrication of mediator-free biosensors, and might find wide potential applications in environmental analysis and biomedical detection.
292 citations
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TL;DR: Nitrogen and sulfur co-doped carbon dots (N,S/C-dots) with high fluorescence quantum yields (FLQY, 25%) was successfully synthesized by a one-step microwave-assisted method and was successfully applied to probe Hg(2+) in living cells, which broaden its application in biological system.
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TL;DR: The proposed sandwich assay benefits from advantageous of a sandwich assay for increased specificity, MB as carriers of affinity ligands for solution-phase recognition and fast magnetic separation, AgNPs for signal amplification, and an electrochemical stripping voltammetry read-out as a simple and sensitive detection.
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TL;DR: A simple and accurate biosensor based on a chemiluminescent (CL)-lateral flow immunoassay (LFIA) method integrated in a smartphone to quantitatively detect salivary cortisol, which could find application in the growing area of home-self-diagnostic device technology for clinical biomarker monitoring.
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TL;DR: A rapid fluorescence "switch-on" assay was developed to detect trace amount of GSH based on carbon dots-MnO2nanocomposites, which was fabricated through in situ synthesis of MnO2 nanosheets in carbon dots colloid solution and demonstrated highly selectivity toward GSH with a detection limit of 300nM.
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TL;DR: In this article, the authors used Fe3O4 magnetic nanoparticles (MNP) as a nano-probe to detect the glycoprotein of Ebola virus (EBOV) as low as 1 ng/mL, which is 100 times more sensitive than the standard strip method.
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TL;DR: Fluorescence probe experiments demonstrated that the peroxidase-like activity of H2TCPP-NiO NPs originated from the generation of OH radical, which may provide great potential applications in biomedicine, biotechnology and environmental chemistry.
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TL;DR: It is the first report to explore a colorimetric Hg(2+) sensing system on the basis of peroxidase mimicking activities of Pt nanoparticles, and one of the most intriguing results is that BSA-stabilized Pt nanozymes demonstrate the ability to sense Hg (2+) ions in aqueous solution without significant interference from other metal ions.
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TL;DR: A simple, highly sensitive and selective fluorometric Hg(2+) sensor based on CDs-labeled oligodeoxyribonucleotide and GO without complicated, costly and time-consuming operations is designed.
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TL;DR: Using graphitic carbon nitride (g-C3N4) nanosheets, an effective and facile fluorescence sensing approach for the label-free and selective determination of chromium (VI) (Cr(VI), which has the potential application for detection of Cr(VI) in lake waters and AA in biological fluids.
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TL;DR: An immunochromatographic test was developed for the simultaneous detection of several compounds in a complex sample matrix in a 'traffic light' format comprising three lines of different colors on a test strip, thereby providing an easy tool with which to identify an analyte of interest based on the visible color of the line formed.
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TL;DR: A fluorescent turn-on nanosensor for lead (II) detection based on biocompatible graphene quantum dots and graphene oxide by employment of Pb(2+)-induced G-quadruplex formation was reported.
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TL;DR: A Raman based biosensor was developed for S. typhimurium and S. aureus detection simultaneously, which results in high sensitivity and specificity, and can be used to detect actual samples.
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TL;DR: This review explores the basic features of these sensing approaches through evaluation of their performance and describes the challenges and opportunities for these unique sensing techniques.
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TL;DR: In this review, the latest novelties in development and application of FRET nanosensors employing QDs are presented.
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TL;DR: A novel and sensitive sensor for the detection of organophosphorus pesticides based on the inner-filter effect (IFE) between gold nanoparticles (AuNPs) and ratiometric fluorescent quantum dots (RF-QDs) is developed.
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TL;DR: A simple and sensitive fluorescent sensor for methyl parathion is developed based on L-tyrosine methyl ester functionalized carbon dots (Tyr-CDs) and tyrosinase system that shows a low detection limit, wide linear range, good selectivity and high reproducibility.
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TL;DR: Current isothermal amplification methods as classified by their enzymatic mechanisms are reviewed, and their advantages, disadvantages, efficiencies, and applications are compared.
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TL;DR: The effects of hydraulic residence time (HRT), reactive brilliant red X-3B (ABRx3) proportion and COD concentration on the electricity production of CW-MFC and the degradation characteristics of ABRX3 were investigated and the highest decolorization rate and electricity production were obtained when HRT was 3 days.
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TL;DR: The obtained results indicate the proposed immunosensor can be used for monitor the differences in PSA concentration in cancer tissue samples which holds great promise in clinical screening of cancer biomarkers.
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TL;DR: Recently, microscale MFCs have received increasing attention as a unique platform for various applications such as powering small portable electronic elements in remote locations, performing fundamental studies of microorganisms, screening bacterial strains, and toxicity detection in water.