Showing papers in "Biosensors and Bioelectronics in 2021"

TL;DR: The key structural components of the virus were presented to provide the audience with an understanding of the scientific principles behind the testing tools and the methods in the early research state.

TL;DR: A specific and sensitive immunosensor for immunoglobulin detection produced against SARS-CoV-2 is developed and the proposed format was also extended to antigen detection, which presents new possibilities for diagnosing COVID-19.

TL;DR: In this paper, the application of potentiometric-based biosensors and classifications of them into four major categories: photoelectrochemical, molecular imprinted polymer, wearable and light-addressable.

TL;DR: This analytical tool has high potentiality for market entry as the first highly sensitive electrochemical immunoassay for SARS-CoV-2 detection in untreated saliva.

TL;DR: The collateral activity against single-stranded DNA reporters of activated Cas12a triggered by RT-LAMP amplicon increases detection sensitivity and makes detection results observable with naked eye, and the opvCRISPR enables detection at nearly single molecule level in 45 min.

TL;DR: The recently developed POC diagnostics integrated or future possibilities of integration with IoMT are discussed with focus on emerging and re-emerging infectious diseases like malaria, dengue fever, influenza A (H1N1), human papilloma virus, Ebola virus disease (EVD), Zika virus (ZIKV), and coronavirus (COVID-19).

TL;DR: A method for rapid and direct optical measurement of SARS-CoV-2 virus particles in one step nearly without any sample preparation using a spike protein specific nanoplasmonic resonance sensor is developed.

TL;DR: A novel nanozyme-based chemiluminescence paper assay for rapid and sensitive detection of SARS-CoV-2 spike antigen, which integrates nanozyme and enzymatic chemilUMinescence immunoassay with the lateral flow strip is developed and provides a high-sensitive point-of-care testing (POCT) approach.

TL;DR: In this paper, a miniaturized plasmonic immunosensor based on toroidal electrodynamics concept was used to detect SARS-CoV-2 virus protein with significantly low as limit of detection (LoD).

TL;DR: This platform provides a facile, fast and general route for sensitive SERS detection of Raman inactive biomacromolecules, which offers great promising utility for in situ and fast point-of-care practical bioassay.

TL;DR: This review article surveys state-of-the-art nanomaterials-based electrochemical sensors and biosensors for the detection and quantification of six classes of significant pharmaceutical compounds, including anti-inflammatory, anti-depressant,Anti-bacterial, anti -viral, pro-fungal, and anti-cancer drugs.

TL;DR: The methods created by different research institutes as well as the commercial devices and kits developed by companies for the detection of SARS-CoV-2 and Middle East respiratory syndrome (MERS) coronavirus are summarized and some promising techniques are proposed.

TL;DR: This review describes how research efforts have led to pioneering developments and are driving the advancement and commercialization of wearable electrochemical sensors: from minimally invasive continuous glucose monitors for chronic disease management to non-invasive sweat electrolyte sensors for dehydration monitoring in fitness applications.

TL;DR: This is the first study to detect SARS-CoV-2 S1 antigen using an LFIA with matched pair consisting of ACE2 and antibody, which can form matched pairs with commercially available antibodies.

TL;DR: Gold nanoparticles (AuNPs) of versatile shapes and morphologies such as nanorods, nanoclusters, nanoflowers, nanostars, nanocages, nanobipyramids and nanowires have been employed as probes to design biosensors enabling detecting various contaminants and allergens.

TL;DR: Rapid label-free electrochemical detection of SARS-CoV-2 antibodies using a commercially available impedance sensing platform is demonstrated and a well-based platform provides a simplified and familiar testing interface that can be readily adaptable for use in clinical settings.

TL;DR: This IgA LFIA immunosensor could be useful for noninvasively monitoring early immune responses to COVID-19 and for investigating the diagnostic/prognostic utility of salivary IgA in the context of large-scale screening to assess the efficacy of SARS-CoV-2 vaccines.

TL;DR: This review covers the remarkable developments in TENG-based biomedical sensing which have arisen in the last octennium, focusing on both in-body and on-body biomedical sensing solutions.

TL;DR: This review provides a general overview of electrochemical MIP-based sensors that have been reported for the detection of pharmaceuticals, pesticides, heavy metals and other contaminants in water samples in the past decade.

TL;DR: The trans-cleavage activity of CRISPR/Cas12a is introduced into an electrochemical biosensor (E-CRISPR), combined with recombinase-assisted amplification (RAA), to establish a cost-effective, specific and ultrasensitive method; namely RAA-based E-CRisPR.

TL;DR: In this article, the authors reviewed recent innovations of aptamer-functionalized metal-organic frameworks (MOFs)-based biosensors and their bio-applications, and provided a brief overview on the integration of MOFs on microfluidic devices.

TL;DR: The enhancement of both stability and sensitivity has been achieved by utilizing two types of MOFs, which laid the foundation for expanding the applications of BFC-based self-powered biosensors.

TL;DR: Advances in electrochemical biosensing platforms towards the detection of SARS-CoV-2 through studying similar viruses are reviewed.

TL;DR: In this article, a 3D self-supporting Z-scheme AgI/Ag/BiOI heterojunction arrays with in-situ formed biocatalytic precipitation (BCP) signal amplification strategy was used to detect chloramphenicol (CAP) detection.

TL;DR: A soft template-directed wet chemical approach was proposed for preparation of 2D MnO2 nanoflakes, in which the morphology can be easily tuned by the template dosage, and not only the oxidase-like activity was discovered, but2D Mn O2 nan oflakes also display a significant peroxidase- like activity.

TL;DR: A sensitive biosensor was developed based on aptamer functionalized polydimethylsiloxane (PDMS) film for the detection of Staphylococcus aureus using surface-enhanced Raman scattering (SERS) technology and a 92.5-110% recovery rate was achieved.

TL;DR: In this article, the authors design and implement different multiplexed versions of their electrochemical microfluidic biosensor by dividing its channel into subsections, creating four novel chip designs for the amplification-free and simultaneous quantification of up to eight miRNAs on the CRISPR-Biosensor X ('X' highlighting the multiplexing aspect of the device).

TL;DR: A SARS-CoV-2 NP-specific rapid diagnostic test is successfully developed, which is expected to be a simple and Rapid diagnostic test for COVID-19.

TL;DR: A novel fiber-optic based label-free biosensor is presented, whose performance were verified through the detection of C-reactive protein (CRP) in serum, based on a long period grating fabricated in a double cladding fiber with a W-shaped refractive index (RI) profile.

TL;DR: A rapid electrochemical diagnostic kit composed of fixed/screen printed electrodes that can detect pathogenic viruses such as SARS-CoV-2 and/or animal viruses through the differentiable fingerprint of their viral glycoproteins at different voltage positions is designed.