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Showing papers in "Biotechnology Advances in 2003"


Journal ArticleDOI
TL;DR: Economics of monoseptic production of microalgae in photobioreactors and the downstream recovery of metabolites are discussed using eicosapentaenoic acid (EPA) recovery as a representative case study.

2,220 citations


Journal ArticleDOI
TL;DR: The decolorization and detoxification potential of WRF can be harnessed thanks to emerging knowledge of the physiology of these organisms as well as of the biocatalysis and stability characteristics of their enzymes.

1,091 citations


Journal ArticleDOI
TL;DR: A closer look will be taken at the mechanisms of both plants in constructed wetlands and the microorganisms in the root zone which come into play when they remove contaminants from wastewater.

1,042 citations


Journal ArticleDOI
TL;DR: The net result of adding bacteria to plants is a significant increase in both the number of seeds that germinate and the amount of biomass that the plants are able to attain, making phytoremediation in the presence of plant growth-promoting bacteria a much faster and more efficient process.

769 citations


Journal ArticleDOI
TL;DR: Maximum algae productivity is required for effective nutrient removal and must be considered as a key area of research, and low harvesting costs are also required for a cost-effective nutrient removal system.

406 citations


Journal ArticleDOI
TL;DR: This paper reviews recent advances in heterotrophic production of EPA by microalgae with an emphasis on the use of diatoms as producing organisms.

367 citations


Journal ArticleDOI
TL;DR: The use of two-peptide antimicrobial peptides as replacement for clinical antibiotics is promising, though their applications in preservation of foods, in veterinary medicine, and in dentistry are more immediate.

308 citations


Journal ArticleDOI
TL;DR: This review focuses on the physiologically active polysaccharopeptides of C. versicolor, which are effective immunopotentiators which are used to supplement the chemotherapy and radiotherapy of cancers and various infectious diseases.

266 citations


Journal ArticleDOI
TL;DR: The present review describes the advances in the use of biological treatment for the destruction of cyanide in gold mill effluents.

265 citations


Journal ArticleDOI
TL;DR: The principles, application and new developing techniques of ISFET-based biosensors are reviewed.

216 citations


Journal ArticleDOI
TL;DR: The safety and acceptability of many widely used solid waste management practices are of serious concern and the probable and relative effects on both public health and environmental safety of tradition and modern landfill technologies will be evaluated with respect to proposed alternative treatment technologies.

Journal ArticleDOI
TL;DR: Here, recent and landmark advances in genetic alteration of members of the ethylene pathway in plants and the physiological consequences of these alterations are examined.

Journal ArticleDOI
TL;DR: This review focuses on methods of producing sponge biomass to overcome supply limitations and production techniques discussed include aquaculture in the sea, the controlled environments of aquariums, and culture of sponge cells and primmorphs.

Journal ArticleDOI
TL;DR: This review highlights all available literature that exists on ornamental Chrysanthemum in vitro cell, tissue and organ culture, micropropagation and transformation.

Journal ArticleDOI
TL;DR: Better understanding of the adenovirus infection and replication kinetics as well as better understanding of complementing cell line physiology and metabolism greatly contributed to improving vector titers and volumetric productivity at higher cell densities.

Journal ArticleDOI
TL;DR: The cell-free system described here bypasses most of the biological processes and lends itself to robotic automation for high-throughput expression of genetic information, thus opening up many possibilities in the post-genome era.

Journal ArticleDOI
TL;DR: Wetlands to promote nitrogen removal, mainly through denitrification but also through burial and plant uptake, offer a sound ecotechnological solution and changes in farming practices and use of wetlands for nitrogen assimilation can reduce nitrogen levels in the River.

Journal ArticleDOI
TL;DR: Improvement of data quality and sustainability of IRM strategies have been targeted in an ongoing partnership between the USEPA Office of Research and Development and the Office of Pesticide Programs that will further enhance the agency's ability to develop sustainable insect resistance management strategies for transgenic field corn producing B. thuringiensis (Bt) insecticidal proteins.

Journal ArticleDOI
TL;DR: Different formats of immunoassays designed for hapten identification and various display technologies available for antibody selection and improvement are examined.

Journal ArticleDOI
TL;DR: What the consequences of multiple-nutrient-limited growth are for industrial processes and how the concept might be applied are discussed.

Journal ArticleDOI
TL;DR: A review of the development of the models and the directions they provide for a comprehensive model of oscillatory metabolism is discussed.

Journal ArticleDOI
TL;DR: The potential application of electrochemical biosensors in monitoring of general toxicity as well as hydrocarbons and heavy metals is surveyed.

Journal ArticleDOI
TL;DR: This review discusses the microbial transformation studies of drugs, correlating them with the corresponding metabolism (biotransformation) in animal systems, and emphasis is placed on the potential of microorganisms to mimic mammalian metabolism.

Journal ArticleDOI
TL;DR: One of the major tasks of biochemical engineering sciences is not developing new know-how for industrial applications, but elucidating the know-why in biochemical engineering by conducting research on the underlying scientific fundamentals.

Journal ArticleDOI
TL;DR: A roundtable was organized to explore the potential role of advances in biotechnology and bioengineering to aid in developing causative relationships between spatial and temporal changes in urbanization patterns and groundwater and surface water quality parameters, and to address aspects of socioeconomic constraints in implementing sustainable exploitation of water resources.

Journal ArticleDOI
TL;DR: There is tremendous potential in the application of DNA microarray technology to screen for endocrine-disrupting compounds, which may have synergistic as well as individual effects, and the complexity of the endocrine system itself.

Journal ArticleDOI
TL;DR: It is found that the two most important engineering aspects to take into account the mass propagation of nematodes are oxygen transfer rate and hydrodynamics to allow mating and to avoid mechanical damage of juveniles in stage 2.

Journal ArticleDOI
TL;DR: This review describes the study on "nitrogen-philic plants", which can grow with nitrogen dioxide as the sole nitrogen source, by screening of naturally occurring plants for the assimilation of nitrogen dioxide and genetic manipulation of plants for those genes involved in the primary nitrate metabolism.

Journal ArticleDOI
TL;DR: This review discusses the gene therapy strategy for the hemoglobinopathies and outlines why lentiviral-derived vectors are particularly suited for this type of application, keeping past failures at gene therapy of these hemoglobinopathy in mind.

Journal ArticleDOI
TL;DR: Self-assembling oligopeptide-coated surfaces and plastic substrate may indicate good water-retaining ability by the cell, and there was no apparent difference in cell adhesion and morphology among cells obtained from lag, exponential and stationary growth phases.