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Showing papers in "Brain Research in 1976"



Journal ArticleDOI
TL;DR: The results of lesion and pharmacological experiments suggest that 5-HT-containing neurons localized in the raphe nuclei of the brain stem participate functionally in the control of slow wave sleep (SWS) 24-27 as well as in a variety of waking behavioral processes s,l°.

881 citations


Journal ArticleDOI
TL;DR: Examination of various biochemical characteristics of the GABAnergic nervous system in the rat brain was made between 15 days of gestation and adulthood, finding the rise in the density of the apparent postsynaptic GABA receptor after 8 days postpartum correlates best with the increase in the activity of glutamic acid decarboxylase, a presynaptic marker.

704 citations


Journal ArticleDOI
James L. Henry1
TL;DR: Results suggest that substance P may be involved in excitatory spinal processes and that its actions may be associated specifically with nociception.

656 citations


Journal ArticleDOI
TL;DR: The organization of the regional connections was outlined in a stereotaxic atlas using the autoradiographic tracing method: the majority of the ascending pathways from the rostral raphe nuclei are directed mainly through a ventrolateral bundle via the ventral tegmental area of Tsai, with some lateral extensions to the substantia nigra, and then through the fields of Forel and the zona incerta.

652 citations


Journal ArticleDOI
TL;DR: A localization of receptor binding to the upper dorsal horn is reported and a fall in opiate receptor binding in this area following dorsal root section of rhesus monkey spinal cord is described.

623 citations


Journal ArticleDOI
TL;DR: It is suggested that morphine acting through the periaqueductal gray may actuate a potent supraspinal modulatory system related to the transmission of information derived from behaviorally aversive stimuli.

598 citations


Journal ArticleDOI
TL;DR: The afferents from each geniculate lamina were found to be segregated into patches, about 500 mum wide, which probably form the anatomical basis for ocular dominance columns, and suggests that the recurrent loop to the LGN is mediated monosynaptically.

534 citations


Journal ArticleDOI
TL;DR: Almost all brain regions investigated contained both noradrenaline and lopamine in measurable amount, however, both catecholamines appeared to be unevenly distributed.

520 citations



Journal ArticleDOI
TL;DR: Two general classes of medium-sized neuron were found in the locus coeruleus in Nissl- and DBH-stained material: multipolar and somewhat smaller fusiform cells; both types of neuron have relatively long thin dendrites which extend well beyond the limits of the nucleus into surrounding neuropil and nuclear areas.

Journal ArticleDOI
TL;DR: While the majority of the monoamine-containing neurons in the transplants died within the first month after transplantation, a significant number of neurons survived for at least half a year in the brain.

Journal ArticleDOI
TL;DR: The extent and time course of degeneration is described and the nature of the reinnervation processes is described; degenerating entorhinal terminals behaved as a population which disappeared randomly at a rate dependent on the fraction of terminals present at any time.

Journal ArticleDOI
TL;DR: The amine mechanisms demonstrated in human brain vessels appear to be principally the same of those shown in more extensive studies on laboratory animals.

Journal ArticleDOI
TL;DR: Using a sensitive radioimmunoassay, the level of substance P is higher in the mesencephalon, hypothalamus and preoptic area than in other regions of the brain and is found in especially high concentrations in the reticular part of the substantia nigra and the interpeduncular nucleus.


Journal ArticleDOI
TL;DR: The frontal lobe connections of the post-Rolandic sensory association areas are investigated and it was found that the caudalmost portion of area 7 has a distinct projection pattern, connecting with the dorsal prearcuate cortex--areas 8B and 46.

Journal ArticleDOI
TL;DR: Subregions of the rat hippocampal slice were investigated in relation to (a) the presence of long-term potentiation and (b) responsiveness to low-frequency stimulation to find areas CA3 and CA1 exhibit response facilitation whereas the dentate gyrus exhibits response depression.

Journal ArticleDOI
TL;DR: The results emphasize the importance of striatonigral projections which recent studies have suggested contain a GABAergic link.

Journal ArticleDOI
TL;DR: Two monkeys were trained to perform 3 kinds of spatial tasks (right-left DR, up-down DR, and conditional position discrimination with delay) and results indicate that there are two types of differential delay units.

Journal ArticleDOI
TL;DR: Isometric responses of individual gastrocnemius muscle units of both fast (F) and slow (S) twitch type were studied during repetitive intracellular stimulation of the innervating motoneurons in anesthetized cats to represent a disenhancement process intrinsic to muscle unit fibers activated in unfused tetani.



Journal ArticleDOI
TL;DR: It is concluded that Stoffels' principle of lamellation holds and, that one pulvinar subdivision projects to several cortical areas, that adjacent Pulvinar subdivisions have overlapping projections to these cortical areas and their layers and that the pulvinars also projects to the same cortical area as DLG but to different layers.

Journal ArticleDOI
TL;DR: The authors' data indicate that granule cells retain a capacity even into adulthood to manufacture, position and assemble postsynaptic components of a synapse and, in concert with reactive afferents, form normal-appearing synapses.

Journal ArticleDOI
TL;DR: A gradient of response magnitude was observed across the movement fields of neurons in the intermediate and deeper layers of the superior colliculus, suggesting that precise saccadic movements are not produced by the discharge of a small population of finely tuned neurons but result from the weighted sum of the simultaneous movement tendenciesproduced by the activity of a large population of less finely tuned neuron.

Journal ArticleDOI
TL;DR: A recent study was able to demonstrate the occurrence of VIP, not only in endocrine-like cells, but also in a rich system of gastrointestinal nerves, some of which had a perivascular localization 12.

Journal ArticleDOI
TL;DR: The frontal areas receiving dopaminergic innervation coincide strikingly with the 'prefrontal cortex' as defined by neuroanatomical studies, which is assumed to be more or less equivalent to the prefrontal cortex of primates and derives direct projections from the amygdala.

Journal ArticleDOI
TL;DR: Findings indicate that the neostriatum has 2 distinct types of spiny neurons with long axons (spiny I and II), some of which may contribute to the efferent system.

Journal ArticleDOI
TL;DR: In all cases, the characteristics of responses to electrical stimulation were studied using the tests of invariance of latency, high frequency following, and collision for determining the orthodromic or antidromic nature of the responses.