British Journal of Neurosurgery 

About: British Journal of Neurosurgery is an academic journal published by Informa. The journal publishes majorly in the area(s): Aneurysm & Medicine. It has an ISSN identifier of 0268-8697. Over the lifetime, 5175 publications have been published receiving 79280 citations.

Learning from Bristol: report of the public inquiry into children's heart surgery at Bristol Royal Infirmary 1984-1995.

Abstract: (2002). Learning from Bristol: report of the public inquiry into children's heart surgery at Bristol Royal Infirmary 1984-1995. British Journal of Neurosurgery: Vol. 16, No. 3, pp. 211-216.

Seizures and epilepsy.

Abstract: Procedure Appropriateness Category Relative Radiation Level CT head without IV contrast Usually Appropriate ☢☢☢ MRI head without IV contrast Usually Appropriate O MRI head without and with IV contrast May Be Appropriate O CT head with IV contrast Usually Not Appropriate ☢☢☢ CT head without and with IV contrast Usually Not Appropriate ☢☢☢ FDG-PET/CT brain Usually Not Appropriate ☢☢☢☢ MEG Usually Not Appropriate O MRI functional (fMRI) head without IV contrast Usually Not Appropriate O HMPAO SPECT or SPECT/CT brain ictal and interictal Usually Not Appropriate ☢☢☢

Biomechanics and neuropathology of adult and paediatric head injury.

Abstract: The objective of this study was to understand the biomechanics in age-related primary traumatic brain injuries (TBI) causing initial severity and secondary progressive damage and to develop strategy reducing TBI outcome variability using biomechanical reconstruction to identify types of causal mechanisms prior to clinical trials of neuro-protective treatment. The methods included the explanation of TBI biomechanics and physiopathological mechanisms from dual perspectives of neurosurgery and biomechanical engineering. Scaling of tolerances for skull failure and brain injuries in infants, children and adults are developed. Diagnostic assumptions without biomechanical considerations are critiqued. Methods for retrospective TBI reconstruction for prevention are summarized. Mechanisms of TBI are based on the differences between the mechanical properties of the head and neck related to age. Skull fracture levels correlate with increasing cranial bone thickness and in the development of the cranial sutures in infants and in adults. Head injury tolerance levels at three age categories for cerebral concussion, skull fracture and three grades of diffuse axonal injuries (DAI) are presented. Brain mass correlates inversely for TBI caused by angular head motions and locations of injurious stresses are predictable by centripetal theory. Improved quantitative diagnosis of TBI type and severity levels depend primarily on age and biomechanical mechanisms. Reconstruction of the biomechanics is feasible and enables quantitative stratification of TBI severity. Experimental treatment has succeeded in preventing progressive damage in animal TBI models. In humans this has failed, because the animal model received biomechanically controlled TBI and humans did not. Clinical similarities of human TBI patients do not necessarily predict equivalent biomechanics because such trauma can be produced in various ways. We recommend 'reverse engineering' for in-depth reconstruction of the TBI injury mechanism for qualitative diagnoses and reduction of outcome variability.

The Westmead Head Injury Project outcome in severe head injury. A comparative analysis of pre-hospital, clinical and CT variables.

Abstract: A prospective study of 315 consecutive patients with a severe head injury was undertaken to study factors contributing to mortality and morbidity, both in the pre-hospital and hospital phases. Entr...

Risk factors for neurosurgical site infections after craniotomy: a critical reappraisal of antibiotic prophylaxis on 4578 patients

Abstract: The objective of this study was to evaluate incidence and risk factors of postoperative infections, with emphasis on antibiotic prophylaxis, in a series of 4578 craniotomies. A prospective database...