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JournalISSN: 0007-1250

British Journal of Psychiatry 

Cambridge University Press
About: British Journal of Psychiatry is an academic journal published by Cambridge University Press. The journal publishes majorly in the area(s): Poison control & Population. It has an ISSN identifier of 0007-1250. Over the lifetime, 21955 publications have been published receiving 1017265 citations. The journal is also known as: Br J Psychiatry & The British Journal of Psychiatry.


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Journal ArticleDOI
TL;DR: The construction of a depression rating scale designed to be particularly sensitive to treatment effects is described, and its capacity to differentiate between responders and non-responders to antidepressant treatment was better than the HRS, indicating greater sensitivity to change.
Abstract: The construction of a depression rating scale designed to be particularly sensitive to treatment effects is described. Ratings of 54 English and 52 Swedish patients on a 65 item comprehensive psychopathology scale were used to identify the 17 most commonly occurring symptoms in primary depressive illness in the combined sample. Ratings on these 17 items for 64 patients participating in studies of four different antidepressant drugs were used to create a depression scale consisting of the 10 items which showed the largest changes with treatment and the highest correlation to overall change. The inner-rater reliability of the new depression scale was high. Scores on the scale correlated significantly with scores on a standard rating scale for depression, the Hamilton Rating Scale (HRS), indicating its validity as a general severity estimate. Its capacity to differentiate between responders and non-responders to antidepressant treatment was better than the HRS, indicating greater sensitivity to change. The practical and ethical implications in terms of smaller sample sizes in clinical trials are discussed.

11,923 citations

Journal ArticleDOI
TL;DR: The development of a 10-item self-report scale (EPDS) to screen for Postnatal Depression in the community was found to have satisfactory sensitivity and specficity, and was also sensitive to change in the severity of depression over time.
Abstract: The development of a 10-item self-report scale (EPDS) to screen for Postnatal Depression in the community is described. After extensive pilot interviews a validation study was carried out on 84 mothers using the Research Diagnostic Criteria for depressive illness obtained from Goldberg's Standardised Psychiatric Interview. The EPDS was found to have satisfactory sensitivity and specificity, and was also sensitive to change in the severity of depression over time. The scale can be completed in about 5 minutes and has a simple method of scoring. The use of the EPDS in the secondary prevention of Postnatal Depression is discussed.

10,857 citations

Journal ArticleDOI
TL;DR: The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.
Abstract: An eleven item clinician-administered Mania Rating Scale (MRS) is introduced, and its reliability, validity and sensitivity are examined. There was a high correlation between the scores of two independent clinicians on both the total score (0.93) and the individual item scores (0.66 to 0.92). The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently. The score also correlated with the number of days of subsequent stay in hospital. It was able to differentiate statistically patients before and after two weeks of treatment and to distinguish levels of severity based on the global rating.

7,398 citations

Journal ArticleDOI
TL;DR: The Clinical Dementia Rating (CRD) was developed for a prospective study of mild senile dementia—Alzheimer type (SDAT), and was found to distinguish unambiguously among older subjects with a wide range of cognitive function.
Abstract: Accurate clinical staging of dementia in older subjects has not previously been achieved despite the use of such methods as psychometric testing, behavioural rating, and various combinations of simpler psychometric and behavioural evaluations The Clinical Dementia Rating (CRD), a global rating device, was developed for a prospective study of mild senile dementia--Alzheimer type (SDAT) Reliability, validity, and correlational data are discussed The CRD was found to distinguish unambiguously among older subjects with a wide range of cognitive function, from healthy to severely impaired

6,428 citations

Journal ArticleDOI
TL;DR: The expectation of mental disorder shows a steep increase with advancing chronological age, and beyond 75 years a large part of this increase is accounted for by disorders associated with degenerative changes in the central nervous system for which the authors lack remedies at the present time.
Abstract: 1. The association between plaque counts in sections of cerebral cortex and measures of intellectual and personality functioning undertaken in elderly subjects during life has been studied. 2. There was no evidence that degenerative changes had contributed significantly to the causation of illness in patients with "functional" psychiatric disorders or delirious states. 3. There is a highly significant correlation between mean plaque counts and scores for dementia and performance in psychological tests. The findings suggest that psychological and pathological indices are closely related to one another, possibly through their common association with the underlying degenerative process in the brain. 4. Among severely demented subjects and those diagnosed clinically as "senile dements", correlations between psychological and pathological measures decline sharply. However, pathological differences between normal, mildly demented, and severely demented subjects appear to be of a quantitative nature. The possibility that there are qualitative differences in this group, inaccessible to present methods of examination, cannot be excluded.

4,058 citations

Performance
Metrics
No. of papers from the Journal in previous years
YearPapers
2023108
2022203
2021157
2020162
2019160
2018166