Showing papers in "Canadian Journal of Chemistry in 2012"
TL;DR: In this article, it was shown that bitumen separation from oil sands is far more efficient with an organic solvent than with the conventional hot water (Clark) process, but the removal of the organic solvent from the bitumen requ...
Abstract: Separation of bitumen from oil sands is far more efficient with an organic solvent than with the conventional hot water (Clark) process, but the removal of the organic solvent from the bitumen requ...
101 citations
TL;DR: Mesoporous silica and organosilica materials are a class of nanostructured materials that have porous structures with tunable nanometer pores, large surface areas, high pore volumes, and, in some c...
Abstract: Mesoporous silica and organosilica materials are a class of nanostructured materials that have porous structures with tunable nanometer pores, large surface areas, high pore volumes, and, in some c...
74 citations
TL;DR: In this article, the use of functionalized ionic liquids as both reaction media and promoters is reviewed, and the authors show that Ionic liquids designed with special functionality can enhance the reaction rate.
Abstract: The recent development in the use of functionalized ionic liquids as both reaction media and promoters is reviewed. Ionic liquids designed with special functionality can enhance the reaction rate, ...
35 citations
TL;DR: In this article, the performance of a photocatalytic reaction is mainly determined by the quality of the photocatalyst, and the quality can significantly enhance the stability and activity of the reaction.
Abstract: The performance of a photocatalytic reaction is mainly determined by the quality of the photocatalyst. For real applications, significantly enhancing the stability and activity of the photocatalyst...
32 citations
TL;DR: Tridentate Schiff base complexes of zinc and calcium were prepared and tested in the ring-opening polymerization of e-caprolactone and rac-lactide to generate biodegradable polymeric materials from... as mentioned in this paper.
Abstract: Tridentate Schiff base complexes of zinc and calcium were prepared and tested in the ring-opening polymerization of e-caprolactone and rac-lactide to generate biodegradable polymeric materials from...
31 citations
TL;DR: This synthesis of the propargyl-isoindolinone core features an aldehyde–alkyne–amine (A3) coupling-based tandem strategy using methyl 2-formylbenzoate, primary aryl amine, and terminal alkyne under Cu(OTf)2 catalysis.
Abstract: Isoindolinone derivatives are important pharmaceutical building blocks in medicinal chemistry. Isoindolo[2,1-a]quinolines are a class of interesting compounds that possess protective effects agains...
29 citations
TL;DR: Dimethylplatinum(II) complexes [PtMe2(NN)], with NN = diimine ligand, can react with dichloromethane or chloroform solvent to give the corresponding organoplatinum(IV) complexes as discussed by the authors.
Abstract: Dimethylplatinum(II) complexes [PtMe2(NN)], with NN = diimine ligand, can react with dichloromethane or chloroform solvent to give the corresponding organoplatinum(IV) complexes [PtClMe2(CH2Cl)(NN)] or [PtClMe2(CHCl2)(NN)], respectively. The products can exist in isomeric forms, corresponding to products of cis or trans oxidative addition. The structures of three dichloromethane adducts and one chloroform adduct are reported.
29 citations
TL;DR: In this article, a new and convenient method for the synthesis of bis(pyrazolyl)methanes by one-pot tandem Knoevenagel-Michael reaction of 3-methyl-1-phenyl-5-pyrazolone with aryl, hetero-aryl, or alkyl aldehydes in...
Abstract: A new and convenient method for the synthesis of bis(pyrazolyl)methanes by one-pot tandem Knoevenagel–Michael reaction of 3-methyl-1-phenyl-5-pyrazolone with aryl, heteroaryl, or alkyl aldehydes in...
29 citations
TL;DR: In this paper, the authors described a one-pot condensation of aldehydes, 2-hydroxynaphthalene-1,4-dione, and 2-n...
Abstract: Facile and convenient procedures for the synthesis of dibenzo[a,i]xanthene-diones have been described. The process employs one-pot condensation of aldehydes, 2-hydroxynaphthalene-1,4-dione, and 2-n...
28 citations
TL;DR: In this article, a green and simple procedure for the thiocynation of aromatic and heteroaromatic rings in the presence of a catalytic amount of citric acid in water is described.
Abstract: A green and simple procedure for the thiocynation of aromatic and heteroaromatic rings in the presence of a catalytic amount of citric acid in water are described. The reactions proceed in high yie...
27 citations
TL;DR: The biocatalytic performance of a cloned cyclohexylamine oxidase derived from Brevibacterium oxydans IH-35A towards structurally different amines was investigated and excellent enantiomeric ratios (>99:1) and good isolated yields of the corresponding (R)-amines were obtained.
Abstract: The biocatalytic performance of a cloned cyclohexylamine oxidase derived from Brevibacterium oxydans IH-35A towards structurally different amines was investigated. Cycloalkyl primary amines, alkyl ...
TL;DR: The 7-hydroxy compounds were found to be more potent and the activity of the C-1 benzoxymethyl analogue exceeded that of narciclasine, which was used as a positive control.
Abstract: Several C-1 homologues of pancratistatin and 7-deoxypancratistatin were synthesized by a phenanthrene–phenathridone oxidative recyclization strategy. The key steps involved the enzymatic dihydroxyl...
TL;DR: In this paper, a simple and straightforward method for reducing the C=C double bond with hydrazine is described, and a number of representative C =C bonds in various steric and electronic environments were examined.
Abstract: A simple and straightforward method for reducing the C=C double bond with hydrazine is described. A number of representative C=C bonds in various steric and electronic environments were examined. S...
TL;DR: A multilayer film based on gold nanoparticles (AuNPs), thionine (Thi), and TiO2graphene (TiO2-Gr) was exploited to develop a highly sensitive amperometric immunosensor for detecting carcinoe....
Abstract: A novel multilayer film based on gold nanoparticles (AuNPs), thionine (Thi), and TiO2–graphene (TiO2–Gr) was exploited to develop a highly sensitive amperometric immunosensor for detecting carcinoe...
TL;DR: In this paper, the authors proposed a route for depolymerization of silicone elastomer surfaces that are rough at the nanometer to micron scales, but there are few efficient routes for their preparation.
Abstract: Silicone elastomer surfaces that are rough at the nanometer to micron scales could be useful for biomaterials, but there are few efficient routes for their preparation. Silicones undergo depolymeri...
TL;DR: In this article, a comparison of benzylidene, benzhydrylidene and fluorenylidsene tert-butybenzylidenes was made.
Abstract: Hydrazine and azapeptide analogs were synthesized effectively by alkylation of alkylidene carbazates and semicarbazones. In comparisons of benzylidene, benzhydrylidene, and fluorenylidene tert-buty...
TL;DR: It was recently discovered that easily available CuSO4·5H2O could be employed as an efficient catalyst towards the coupling reactions of terminal alkynes with H-phosphonates, which finally led to t...
Abstract: It was recently discovered that easily available CuSO4·5H2O could be employed as an efficient catalyst towards the coupling reactions of terminal alkynes with H-phosphonates, which finally led to t...
TL;DR: In this article, the results obtained in the synthesis of thioamide and a-ketothioamides by a modification of the Willgerodt-Kindler reaction, under solvent-free and non-catalyst conditions using IR energy as a source of activation, are presented.
Abstract: In this paper, the results obtained in the synthesis of thioamides and a-ketothioamides by a modification of the Willgerodt-Kindler reaction, under solvent-free and noncatalyst conditions using IR energy as a source of activation, are presented. The use of IR energy in these reactions has been shown to lead to a mixture of thioamide and a-ketothioamide as the main products in most cases, with the latter predominating. The yields of a-ketothioamides from most of these reac- tions are better than those reported previously. To the best of our knowledge, this is the first time that IR energy has been applied to promote the Willgerodt-Kindler reaction.
TL;DR: Sulfonated multiwalled carbon nanotubes (MWCNTs) were synthesized by chemical vapor deposition (CVD) as a new and facile one-pot method using acetylene (as the CNT precursor), thiophene (as sul...
Abstract: Sulfonated multiwalled carbon nanotubes (MWCNTs) were synthesized by chemical vapor deposition (CVD) as a new and facile one-pot method using acetylene (as the CNT precursor), thiophene (as the sul...
TL;DR: In this article, the authors cover recent literature on radical perfluoroalkylation reactions of aromatic nuclei in organic and aqueous media, focusing on radical aromatic perfluoralkyla...
Abstract: This account intends to cover recent literature on radical perfluoroalkylation reactions of aromatic nuclei in organic and aqueous media. Emphasis will be placed on radical aromatic perfluoroalkyla...
TL;DR: A facile synthesis of polysubstituted pyrroles from tosylmethyl isocyanide (TOSMIC) and readily synthesized vinyl azides was developed.
Abstract: A facile synthesis of polysubstituted pyrroles from tosylmethyl isocyanide (TOSMIC) and readily synthesized vinyl azides was developed. The reaction proceeded under mild conditions in the presence ...
TL;DR: Ionic ligands derived from a salen ligand containing two proximal 1,3-disubstituted imidazolium ionic liquid cores form cobalt(III) complexes capable of selectively oxidizing veratryl alcohol as mentioned in this paper.
Abstract: Ionic ligands derived from a salen ligand containing two proximal 1,3-disubstituted imidazolium ionic liquid cores form cobalt(III) complexes capable of selectively oxidizing veratryl alcohol, a li...
TL;DR: In this paper, a simple, atom economical, and scalable synthesis of 2,4,5-trisubstituted imidazoles from benzil, aldehydes, and ammonium acetate is shown to proceed readily in methanol with high yield.
Abstract: Operationally simple, atom economical, and scalable synthesis of 2,4,5-trisubstituted imidazoles from benzil, aldehydes, and ammonium acetate is shown to proceed readily in methanol with high yield...
TL;DR: In this article, graphite nanostructures are prepared by thermolysis of a prepared polyacrylamide gel, which was prepared by radical chain polymerization and the synthesis of the nanostructure.
Abstract: In the present work, graphite nanostructures are prepared by thermolysis of a prepared polyacrylamide gel. The gel was prepared by radical chain polymerization and the synthesis of the nanostructur...
TL;DR: In this paper, three kinds of nano-baskets including 1,2alternate and cone conformers of di-ionizable p-tert-butylcalix[4]arene-1,2-crown-3 were synthesized and the competitive solvent extractions of alkali and alkaline earth metal cations were studied.
Abstract: Three kinds of nano-baskets including 1,2-alternate and cone conformers of di-ionizable p-tert-butylcalix[4]arene-1,2-crown-3 and the cone conformer of p-tert-butylcalix[4]arene-1,2-thiacrown-3 were synthesized and the competitive solvent extractions of alkali and alkaline earth metal cations were studied. The novelty of this study is including three binding units of the calixarene’s bowl, the crown ether’s ring, and electron-donor ionizable moieties in a unique scaffold, in which their sizes were selected based upon their complexation ability to show equal binding tendency towards the cations. The objective of this work is to assess the extraction efficiency, selectivity, and pH1/2 of such complexes. The results of solvent extraction experiments indicated that these compounds were effective extractants of alkali and alkaline earth metal cations. Their selectivities were greatly influenced by the acidity of the solution and the conformations of the calixcrown. One conformer was highly selective to Na+ and...
TL;DR: In this paper, a TGA-capped CdTe nanoparticles were synthesized in aqueous medium, and their application as fluorescence probes in the detection of adenine and guanine was studied.
Abstract: Thioglycolic acid (TGA)-capped CdTe nanoparticles (NPs) were synthesized in aqueous medium, and their application as fluorescence probes in the detection of adenine and guanine was studied. The TGA...
TL;DR: In this paper, the synthesis of (Z)-1,2-dichloroalkene analogues from mucochloric acid was reported, which is a more versatile approach.
Abstract: (Z)-1,2-Dihaloalkenes are thermodynamically disfavoured of the two stereoisomers. This paper reports the synthesis of some (Z)-1,2-dichloroalkene analogues from mucochloric acid. A more versatile a...
TL;DR: The synthesis of the pharmaceutical (R)-tolterodine is reported using lithiation/borylation-protodeboronation of a homoallyl carbamate as the key step and it was found that the latter arrangement was considerably better than the former.
Abstract: The synthesis of the pharmaceutical (R)-tolterodine is reported using lithiation/borylation-protodeboronation of a homoallyl carbamate as the key step. This step was tested with two permutations: an electron-neutral aryl Li-carbamate reacting with an electron-rich boronic ester and an electron-rich aryl Li-carbamate reacting with an electron-neutral boronic ester. It was found that the latter arrangement was considerably better than the former. Further improvements were achieved using magnesium bromide in methanol leading to a process that gave high yield and high enantioselectivity in the lithiation/borylation reaction. The key step was used in an efficient synthesis of (R)-tolterodine in a total of eight steps in a 30% overall yield and 90% ee.
TL;DR: In this paper, the synthesis and characterization of the first heteroleptic pyrrolide/2,2′-bipyridyl complexes of ruthenium(II) were reported.
Abstract: The synthesis and characterization of the first heteroleptic pyrrolide/2,2′-bipyridyl complexes of ruthenium(II) are reported. Pyrroles substituted at the 2-position with X = O functionality react ...
TL;DR: In this article, the interaction strength of hydrogen-bonded complexes at the B3LYP/6-311++G(d,p) level was analyzed in accordance with routine spectroscopy events, such as the red-and blue-shifts on the stretch frequencies of the proton donors (HF and HCF3).
Abstract: This work presents a theoretical study about the interaction strength of the hydrogen-bonded complexes C2H4O···HF, C3H6O···HF, C2H4O···HCF3, and C3H6O···HCF3 at the B3LYP/6–311++G(d,p) level. The structures, hydrogen bond energies, charge transfers, and dipole moments of these complexes were analyzed in accordance with routine spectroscopy events, such as the red- and blue-shifts on the stretch frequencies of the proton donors (HF and HCF3). The ChelpG atomic charges were used to quantify the charge-transfer fluxes from electron donor (O) towards to acceptors (HF or HCF3). Moreover, the topological calculations on the basis of the quantum theory of atoms in molecules (QTAIM) approach were also used to unveil the hydrogen bond strength (O···H), mainly in the determination of their electronic densities and Laplacian shapes.