scispace - formally typeset
Search or ask a question

Showing papers in "Cell Biology International Reports in 1992"


Journal ArticleDOI
TL;DR: Transforming growth factor-beta 1 inhibited secretion of human hepatocyte growth factor (hHGF), which is also known as scatter factor or fibroblast-derived tumor cytotoxic factor, by MRC-5 cells, and was more potent than that of dexamethasone.

76 citations


Journal ArticleDOI
TL;DR: The interaction of pollen tube MTs with mAb 6-11B-1 suggested that acetylation of alpha-tubulin correlates well with the putative arrays of stable MTs.

53 citations


Journal ArticleDOI
TL;DR: The idea that 'functional' attachments are the only kind that exist is explored: ' functional' attachments involving active transcription units might be stable enough to organize chromatin during both interphase and mitosis, but 'dynamic' enough to allow duplication of attached sequences without disrupting loops.

48 citations


Journal ArticleDOI
TL;DR: In conclusion, partial thermoprotection of bovine embryos from heat shock can be achieved in vitro by administration of GSH, while taurine is only slightly effective.

47 citations


Journal ArticleDOI
TL;DR: A simple one step centrifugation method was developed for purification of primordial germ cells (PGCs) of chick embryos and the purity was 86%, which was 22 times that obtained previously.

41 citations



Journal ArticleDOI
TL;DR: Only HuH-6 Clone 5 cells were stimulated by recombinant hHGF, a potent mitogen for rat and human hepatocytes in primary culture, which caused dose-dependent increases in cell number and DNA synthesis of cells.

40 citations


Journal ArticleDOI
TL;DR: Direct evidence indicates that despite its lower mitogenic activity the action of IGF-II is mediated through IGF-I receptors, and the galactopoietic activity of Des-3-IGF-I was studied in an organ culture of bovine lactating mammary glands using lactogen-responsive fat synthesis as a test.

40 citations


Journal ArticleDOI
TL;DR: This electron microscopy review documents the in situ cytochemical localization of important nuclear structures and relates this to the important nuclear functions of RNA transcription and processing.

38 citations


Journal ArticleDOI
TL;DR: Results identified ALA, LF and TF as possible intrinsic factors associated with regulation of mammary epithelial cell proliferation in both the absence and presence of 10% fetal bovine serum (FBS).

35 citations


Journal ArticleDOI
TL;DR: The core filament nuclear matrix structure may not completely disassemble at mitosis but, rather, that parts remain as a structural network connected to chromosomes and other mitotic structures that may, in turn, serve as the core structures on which the nuclear matrices of daughter cells are built.


Journal ArticleDOI
TL;DR: There is evidence that adhesive phenomena can contribute at least in part to the selective patterns of spread shown by a variety of tumour cell types.

Journal ArticleDOI
TL;DR: Both homodimers play an important role in chondrocyte differentiation and together with IGF-I interact in the regulation of longitudinal bone growth.

Journal ArticleDOI
TL;DR: It is concluded that oxygen free-radical scavengers are potent inhibitors of the production of macrophage-mediated angiogenic activity.

Journal ArticleDOI
TL;DR: It is proposed that the inhibition of glycolysis was due to the high ATP/ADP ratio of the lungs of the nicotine exposed rats.

Journal ArticleDOI
TL;DR: In an in vitro model, capillary endothelial cells were grown in fibrin matrix containing fibronectin or hyaluronic acid and the study of co-localization of nucleus and actin filaments showed different cell behaviours.

Journal ArticleDOI
TL;DR: VIP modulates simultaneously two disparate cellular events, namely the cell proliferation and differentiation of the RPE, however, with different potencies, and the lowest concentrations of VIP showing significant stimulatory effect oncell proliferation and melanin synthesis are 5x 10(-11) M and 5 x 10(-9)M, respectively.

Journal ArticleDOI
TL;DR: The active Balbiani ring (BR) genes in the giant puffs in Chironomus salivary glands can be visualized in three dimensions within the cell nucleus, indicating that the nucleosomes unfold and refold during transcription.

Journal ArticleDOI
TL;DR: Sphingomyelin liposomes and brain microsomes were oxidized by exposure to hydrogen peroxide and ferrous ion and Sodium ferulate effectively inhibited TBAR formation, protected Na(+)-K( +)-ATPase activity and prevented the oxidative modification of SH groups.

Journal ArticleDOI
TL;DR: An attractive hypothesis has been suggested that individual loops correspond to the functional genomic domains (Cook, 1989) and it was easy to explain how the preferential sensitivity to DNase I could be maintained within the limited though large areas of the genome.

Journal ArticleDOI
TL;DR: It is concluded that cAMP initially activates predominantly the apical Cl- channel and the basolateral K+ channel in colon cancer cell lines, causing a decrease of the cellular Cl and K content in high-K (high-Cl) cells.

Journal ArticleDOI
TL;DR: A cell culture system for the study of human serum growth factors is described, based on a diploid human embryonic lung fibroblast cell strain with a finite life span, which retains its responsiveness to growth stimuli during in vitro aging, although the net proliferative effect decreases as they approach senescence.

Journal ArticleDOI
TL;DR: The karyotypic patterns before and after the crisis show that the translocation together with expression of SV40 T-antigen is not sufficient for direct immortalization.

Journal ArticleDOI
TL;DR: It is demonstrated that IPNV appear internalized within vesicular compartments which are located peripherally in CHSE-214 cells, and suggest that endocytosis may be involved during the initiating events in the productive IPNV infection.

Journal ArticleDOI
W You1, S Abe, E Davies
TL;DR: When conventional, high ionic strength buffers were used for the isolation of polysomes from pea roots, only about 10% were retained in the detergent-insoluble pellet, and they were not degraded by endogenous RNase.

Journal ArticleDOI
TL;DR: Triton X-100-extracted human skin fibroblasts were exposed to human immunodeficiency virus type 1 protease and analysed by 2D-gel electrophoresis and immunofluorescence microscopy, finding prominent stress fibers and chromatin structure seemed to be rather resistant to the action of this protease.

Journal ArticleDOI
TL;DR: The adenylate cyclase system present in particulate fractions prepared from two planarian species was tested for sensitivity to various neurotransmitters, suggesting the presence in planarians of a serotonin receptor of the type 5-HT1A.


Journal ArticleDOI
TL;DR: The data suggest that differences in functional responses elicited in monocytes by all three factors may be dependent on different routes on nuclear signalling employed by the factors.