Showing papers in "Československá patologie in 1975"

[Small-cell carcinoma of the larynx].

Abstract: In a 69-year-old man by biopsy and for the first time on necropsy a primary small-cell carcinoma of the laryngeal ventricle with metastases into the liver was detected and confirmed. Under the electron microscope in the cells endocrine granules were found which were not argyrophil.

Jejunal mucosa in children with mucoviscidosis

Abstract: Thirty-eight specimens obtained by jejunal biopsy from 22 children suffering from mucoviscidosis were examined by histochemical techniques. In 27% of the patients the findings were within normal limits. In 18% of cases, associated coeliacal sprue was disclosed. The remaining cases displayed slight morphological abnormalities associated with trehalase and/or lactase deficiency, and in 41% there was hypersecretion of viscous mucus filling up dilated crypts and adhering to the surface of villi. The findings as observed in enterobiopsis are not pathognostic of mucoviscidosis. They however, should make one to think of it, particularly if trehalase and/or lactase deficiency is found associated with hypersecretion of viscous mucus and an almost normal morphological appearance. Neither normal findings nor that of coeliacal sprue exclude the diagnosis of mucoviscidosis. It appears that malabsorption in mucoviscidosis is not only pancreatogenic; the intestinal mucosa may be contributory to a various degree as well.

Analysis of motivation in attempted suicides of sniffing addicts

Abstract: The authors examined a group of 30 addicts, each of whom had attempted a suicide, once at least, irrespective of the mode of performance. They analysed the motivation and the causes leading the adolescent addicts to suicidal attempts. The suicidal attempts were shown to occur under acute intoxication in 83.3 per cent of cases. Most frequently, the mode of the suicidal attempt was drastic, as e.g. cutting the antebrachial and the wrist veins in 56.6 per cent of cases. In 43.3 per cent of cases there occurred mild encephalopathies. A history of delinquent behaviour was recorded in 63.3 per cent of cases. Eighty per cent of the addicts originated from defective families or had other adverse social conditions. In 80 per cent addiction of psychotropic substances of more than one year duration was noted. Addiction of more than one drug was recorded in 90 per cent of cases. Most probably, volatile psychotropic substances act as "accelerators" in this connection, deteriorating the personality alterations of encephalopathic and psychopathic origin already present, thus conditioning the motivation of suicidal attempts. This finding may be of significance in aiding the forensic psychology and the medicolegal expertise of realized suicides. Language: sk

Pathologic anatomy at the University in Prague before 1882

Abstract: The author analyzed a group of 156 pedestrians (70 men and 86 women) above 50 years (Me = 72 years in men and 72.5 years in women) who died in 1967-1972 as a result of traffic accidents in the catchment area of the University Hospital in Prague 10. Head injuries were recorded in 73%, injuries of the chest in 62%, of the abdomen in 30%, of the spine in 26%, of the pelvis in 52%, of the upper extremities in 26% and of the lower extremities in 51% of the injured. In 20 (12.8%) a single injury was involved, in 136 (97.2%) multiple injuries, most frequently injuries of three parts of the body were observed - in 43 (27.5%) of the injured. The curve illustrating the number of surviving subjects in relation to the time which had elapsed since the injury displayed two definite and two indicated inflexions suggesting increased lethality. The first definite inflexion was between the second and third hour after injury and in those who died during this period fractures of the spine, bones of the lower extremities and pelvic bones with retroperitoneal bleeding were more frequent. The second definite inflexion was 36-48 hours after injury and in the patients pulmonary complications (atelectases, incipient inflammations) were more frequent. The indicated inflexion which was on the 9th day after injury was due to bronchopneumonias which were often observed at that time. Due to the small number of observations the authors were unable to interpret the infexions found on the 7th and 11th day after injury. Language: cs

[The so-called immunologic classification of non-Hodgkin's malignant lymphoma].

Abstract: The so-called immunologic classification of malignant lymphomas was used in 100 of suitable cases. Without the simultaneous use of immunocytological methods the classification was applicable with certain restrictions only, but, in general the entire classification scheme could be used in routine bioptic practice. The so-called immunologic classification permits a more accurate determination of the nature of the neoplasms and a larger flexibility in classifying them considering the possible trend of alterations that may occur during the course of the disease. Some difficulties and points of confusion have been discussed.