Showing papers in "Československá patologie in 1984"

Electron microscopy morphometric analysis of the effect of immobilization stress on the structure of the myocardium in rats belonging to 2 age groups

Abstract: 13 month-old and 25 month-old Wistar rats were exposed to immobilisation stress and compared with a control group of animals. The most impressive influence was found in mitochondria but there were not any significant changes of myofibrils. The number of mitochondria decreased significantly as well as their relative cytoplasmic volume. Absolute mitochondrial volume increased simultaneously. Difference in age of animals resulted in greater mitochondrial sensibility to stress condition in 25 month-old rats.

Carcinoma of the hypophysis with acromegaly

Abstract: A 38-year old man deceased after being operated on recurring pituitary adenoma removed 13 years ago. Autopsy showed a massive spread of tumour on dura and in subarachnoid space. Growth hormone producing cells were found prevailing in the primary tumour as well as in secondaries by immunohistochemistry and immunofluorescence which concurred with acromegaly. Many cells produced prolactin. The tumour spreading discontinually in subdural and subarachnoid space was taken for a carcinoma.

[The first report of "senile" amyloidosis of the heart--I. Soyka, 1876, Prague].

Abstract: Isidor Soyka (1850--1889) described, as first, in 1876 in a Prague medical journal the lesion, which is nowadays termed, "senile cardiac amyloid". Information regarding both the original paper and the author is presented.

[An aorto-esophageal fistula in a patient with malignant lymphogranuloma].

Abstract: A 25-year-old man suffering from lymphogranuloma malignum received mediastinal radiotherapy in a dose of 3,380 R (827 mC/1 kg). About 2,5 years later fatal gastro-intestinal haemorrhage occurred from a aortooesophageal fistula. Aortic necrosis of media and intima with G+ cocci was found, as well as adventitial fibrosis with radiation fibroblasts. Assisting mechanisms of aortic damage by therapeutic doses of radiation were discussed.

Monstrous epithelium in the seminal vesicles and epididymis

Abstract: Monstrous epithelial cells in seminal vesicles, causing diagnostical embarrassment , occur sometimes in fine needle-aspirates of prostate gland. Their frequency was studied in a group of autopsies (6 boys of the age from 6 hours to 10 years, mean age 3,1 years and 34 adult men of the age from 42 to 91 years, mean age 68,4 years). Monstrous cells did not occur in boys but were found in 73,5% of adults. There were similar epithelial monstrosities in epididymis simultaneously. Most of them were found in efferent ductuli (in 76,4%). Big monstrous epithelial cells with conspicuous irregular hyperchromatic nuclei are to be distinguished cautiously from the neoplastic ones. They may be caused by ageing and hormonal influence above all (in analogy to Arias-Stella phenomenon in women).