Journal•ISSN: 0009-2797
Chemico-Biological Interactions
Elsevier BV
About: Chemico-Biological Interactions is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Medicine & Oxidative stress. It has an ISSN identifier of 0009-2797. Over the lifetime, 8884 publications have been published receiving 276427 citations.
Topics: Medicine, Oxidative stress, Apoptosis, Glutathione, Lipid peroxidation
Papers published on a yearly basis
Papers
More filters
TL;DR: This review examines the evidence for involvement of the oxidative stress in the carcinogenesis process and the role of enzymatic and non-enzymatic antioxidants in the process of carcinogenesis as well as the antioxidant interactions with various regulatory factors.
5,937 citations
TL;DR: The antioxidant activity of curcumin was determined by employing various in vitro antioxidant assays such as 1,1-diphenyl-2-picryl-hydrazyl free radical (DPPH*) scavenging, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, N,N-dimethyl-p-phenylenediamine dihydrochloride
1,464 citations
TL;DR: ROS homeostasis is described, principles of their investigation and technical approaches to investigate ROS-related processes are described, and a classification of oxidative stress based on its intensity is proposed.
1,036 citations
TL;DR: The higher redox potential benzoquinones and naphthoquinones are the most cytotoxic presumably because of their higher electrophilicty and thiol reactivity and/or because the quinones or GSH conjugates are more readily reduced to semiquinones which activate oxygen.
989 citations
TL;DR: Treatment with an inhibitor, buthionine sulfoximine (BSO), of gamma-glutamylcysteine synthetase leads to decreased cellular GSH levels, and its application can provide a useful experimental model of GSH deficiency.
880 citations