Showing papers in "Chest in 2008"
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TL;DR: This article discusses the prevention of venous thromboembolism (VTE) and is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
3,944 citations
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TL;DR: Guyatt et al. as mentioned in this paper presented the pharmacokinetics and pharmacodynamics of vitamin K antagonists (VKAs) and provided specific management recommendations for the first 1 or 2 days for most individuals.
2,105 citations
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TL;DR: This chapter about treatment for venous thromboembolic disease is part of the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition) and indicates that the benefits do or do not outweigh risks, burden, and costs.
1,985 citations
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TL;DR: Lung ultrasound can help the clinician make a rapid diagnosis in patients with acute respiratory failure, thus meeting the priority objective of saving time.
1,510 citations
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TL;DR: A systematic review of the literature demonstrated a very poor relationship between CVP and blood volume as well as the inability of CVP/DeltaCVP to predict the hemodynamic response to a fluid challenge.
1,295 citations
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TL;DR: The key recommendations in this article include bridging anticoagulation with therapeutic-dose subcutaneous (SC) LMWH or IV UFH over no bridging during temporary interruption of VKA therapy and continuing aspirin and clopidogrel in the perioperative period.
843 citations
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TL;DR: This chapter about antithrombotic therapy in atrial fibrillation (AF) is part of the American College of Chest Physicians Evidence-Based Guidelines Clinical Practice Guidelines (8th Edition).
777 citations
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TL;DR: The article does not provide specific management recommendations; however, it does highlight important practical aspects related to antiplatelet therapy, including the optimal dose of aspirin, the variable balance of benefits and hazards in different clinical settings, and the issue of interindividual variability in response toAntiplatelet drugs.
752 citations
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TL;DR: In this paper, the recognition, treatment, and prevention of heparin-induced thrombocytopenia (HIT) is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
745 citations
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TL;DR: In this paper, the management of venous thromboembolism (VTE) and thrombophilia, as well as the use of antithrombotic agents, during pregnancy is discussed.
744 citations
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TL;DR: Within this chapter, the majority of recommendations are separate for neonates and children, reflecting the significant differences in epidemiology of thrombosis and safety and efficacy of therapy in these two populations.
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TL;DR: Three parenteral direct thrombin inhibitors and danaparoid are approved as alternatives to heparin in HIT patients and fondaparinux binds only to antithrombin; therefore, HIT and osteoporosis are unlikely to occur.
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TL;DR: In this article, the authors found that VKA therapy, targeted international normalized ratio (INR) of 2.5 (range, 2.0-3.0), is associated with a lower risk of bleeding than therapy targeted at an INR > 3.0.
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TL;DR: A simulation-based educational program significantly improved the quality of care provided by residents during actual ACLS events and there is a growing body of evidence indicating that simulation can be a useful adjunct to traditional methods of procedural training.
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TL;DR: The proceedings of a multidisciplinary workshop on anxiety and depression in COPD aimed to shed light on the current understanding of these comorbidities, and outline unanswered questions and areas of future research needs.
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TL;DR: In this literature review, the data are consistent with a reduction in mortality rates in general populations of patients with ALI/ARDS over the last 10 years.
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University of Toronto1, University of California, San Francisco2, University of Alberta3, University of Rochester4, University of Cincinnati5, University of South Florida6, Mayo Clinic7, State University of New York System8, University of California, Los Angeles9, Université de Montréal10, Yale University11, American College of Chest Physicians12
TL;DR: The substantial prevalence of WRA supports consideration of the diagnosis in all who present with new-onset or worsening asthma, followed by appropriate investigations and intervention including consideration of other exposed workers.
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TL;DR: This article about treatment and prevention of stroke is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
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TL;DR: There is a need for further research to fully demonstrate a causal role for OSA in the development and severity of type 2 diabetes, and future studies must carefully consider the confounding effects of central obesity in examining the link between OSA and alterations in glucose metabolism.
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TL;DR: EBUS-TBNA can be used to accurately sample and stage patients with clinical stage 1 lung cancer and no evidence of mediastinal involvement on CT and PET and the negative predictive value was 98.9%.
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TL;DR: The importance of discussing prognosis effectively, the key role of the integrated interdisciplinary team in this communication, and the importance of assessing spiritual needs and addressing barriers that can be raised by cross-cultural communication are emphasized.
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TL;DR: A structured clinical assessment incorporating advanced cardiac imaging with PET scanning or CMRI is more sensitive than the established criteria for the identification of CS in ambulatory patients with preserved cardiac function, who appear to be at low risk for short-term mortality.
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TL;DR: Lung US scans carried out in the emergency department of the ED detect occult PTX and its extension with an accuracy that is almost as high as the reference standard (CT scanning).
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TL;DR: The new and updated recommendations are provided and several important changes that are made in the guideline development process are reviewed, including an attempt to increase the participation of female authors and contributors from outside North America.
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TL;DR: In this article, the authors provide a context and rationale for improving the quality of communication with family members and to provide practical, evidence-based guidance on how to conduct this communication in the ICU setting.
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TL;DR: At presentation, patients with arm DVT have less often clinically overt PE than those with lower-limb DVT, but their 3-month outcome is similar, and those with cancer have the worse outcome.
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TL;DR: This chapter outlines the rationale for development of new antithrombotic agents, describes the new antiplatelet, anticoagulant, and fibrinolytic drugs, and provides clinical perspectives on the opportunities and challenges faced by these novel agents.
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TL;DR: If one aims at changing physical activity habits in the daily life of COPD patients, the contribution of long-lasting programs might be important.
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TL;DR: The 6MWD helps predict mortality primarily in patients with severe COPD and the oxygen desaturation profile during the 6MWT appears to be of less relevance than in other lung diseases and than the resting Pao2.