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Showing papers in "Chest in 2009"



Journal ArticleDOI
01 Jul 2009-Chest
TL;DR: The recommendations of the IASLC International Staging Committee for the definitions for the TNM descriptors and the stage grouping in the new non-small cell lung cancer staging system are reviewed.

819 citations


Journal ArticleDOI
01 Mar 2009-Chest
TL;DR: This overview identifies the gaps in the understanding of RV failure and attempts to fill them, when possible, and aims to encourage the pulmonary hypertension research community to direct some of their attention to the RV, in parallel to their focus on the pulmonary vasculature.

627 citations



Journal ArticleDOI
01 Aug 2009-Chest
TL;DR: In this article, the emergence of resistant bacilli (totally drug-resistant [TDR] or super extensively drug resistant [XDR] tuberculosis [TB] strains) among patients with multidrug-resistant TB (MDR-TB) was documented.

525 citations


Journal ArticleDOI
01 Feb 2009-Chest
TL;DR: It is demonstrated that M-mode ultrasonography is a reproducible method for assessing hemidiaphragmatic movement.

511 citations


Journal ArticleDOI
01 Jan 2009-Chest
TL;DR: The evidence that accelerating aging of lung in response to oxidative stress is involved in the pathogenesis and progression of COPD, particularly emphysema is reviewed.

500 citations


Journal ArticleDOI
01 Feb 2009-Chest
TL;DR: Mucin glycoprotein overproduction and hypersecretion are common features of chronic inflammatory airway disease, and this has been the underlying rationale to investigate the mechanisms of mucin gene regulation and mucin secretion.

465 citations


Journal ArticleDOI
01 Jul 2009-Chest
TL;DR: IPF patients with emphysema exhibited higher mortality compared with those with IPF without emphySEma, and this dire prognosis seems to be at least partially associated with the development of severe pulmonary arterial hypertension.

423 citations


Journal ArticleDOI
01 Jul 2009-Chest
TL;DR: Both early and late fluid management of septic shock complicated by ALI can influence patient outcomes.

384 citations


Journal ArticleDOI
01 Jun 2009-Chest
TL;DR: In patients with alveolar consolidation displayingAir bronchograms on an ultrasound, the dynamic air bronchogram indicated pneumonia, distinguishing it from resorptive atelectasis, increasing the understanding of the pathophysiology of lung diseases within the clinical context and decreases the need for fibroscopy in practice.

Journal ArticleDOI
01 Nov 2009-Chest
TL;DR: It is proposed that the evaluation of patients with RA-ILD should focus on identifying those with UIP pattern on HRCT scans, as these patients are likely to carry a worse prognosis.

Journal ArticleDOI
01 Aug 2009-Chest
TL;DR: The diagnostic yield of EBUS-guided TBNA is superior to TBNA using a standard 19-gauge needle for sampling of mediastinal lymph nodes in patients with a clinical suspicion of sarcoidosis.

Journal ArticleDOI
01 Oct 2009-Chest
TL;DR: A-predominance suggests that fluid may be given without initial concern for the development of hydrostatic pulmonary edema, and this bedside potential will be appreciated by those intensivists who envision fluid therapy based on low PAOP values and who consider that using the concept of a safety factor provided by lung ultrasound is logical.

Journal ArticleDOI
01 Apr 2009-Chest
TL;DR: Chronic cough and sputum production and decreased FEV(1) were independently associated with an increased risk of frequent exacerbations and frequent hospitalizations, including severe exacerbations requiring hospitalizations.

Journal ArticleDOI
01 Jun 2009-Chest
TL;DR: In this article, the authors used a global rating-of-change questionnaire (GRCQ) to assess patients' perceptions of change in their respiratory symptoms after TIS treatment, and mapped the mean change from baseline CFQ-R-Respiratory scores onto the GRCQ to estimate the minimal clinically important difference (MCID).

Journal ArticleDOI
01 Jun 2009-Chest
TL;DR: B-line resolution appears to occur real-time as fluid is removed from the body, and this change was statistically significant, and these data support thoracic ultrasound as a useful method for evaluating real- time changes in EVLW and in assessing a patient's physiologic response to the removal of fluid.

Journal ArticleDOI
01 Mar 2009-Chest
TL;DR: A diagnosis of PE should be considered in patients with exacerbation severe enough to warrant hospitalization, especially in those with an intermediate-to-high pretest probability of PE.

Journal ArticleDOI
01 Sep 2009-Chest
TL;DR: Livestock farmers have an increased risk of chronic bronchitis, COPD, and reduced FEV, and atopy appears more susceptible to develop farming-related COPD; a role for specific biological agents cannot be excluded.

Journal ArticleDOI
01 Sep 2009-Chest
TL;DR: OSA is prevalent in patients with IPF and may be underrecognized by primary care providers and specialists, and formal sleep evaluation and polysomnography should be considered in patientswith IPF.

Journal ArticleDOI
01 May 2009-Chest
TL;DR: In patients with CF, PA airway infection, moderate-to-severe lung disease, and no recent use of antipseudomonal antibiotics or azithromycin, 28-day treatment with AZLI significantly improved respiratory symptoms and pulmonary function, and was well tolerated.

Journal ArticleDOI
01 Jan 2009-Chest
TL;DR: Quantitative CT-determined air trapping in asthmatic subjects identifies a group of individuals at high risk for severe disease, including history of pneumonia, neutrophilic inflammation, and atopy.

Journal ArticleDOI
01 Oct 2009-Chest
TL;DR: Almost one-half of the patients with CB/COPD had coexisting metabolic syndrome, with a slightly lower frequency in patients with severe COPD, which is associated with an increase in the levels of some systemic inflammatory markers and physical inactivity, independent of lung function impairment.

Journal ArticleDOI
01 Jan 2009-Chest
TL;DR: Experimental and clinical data suggest that glucocorticoid tissue resistance may also play an important role in the diagnosis of adrenal failure and the role of corticosteroid therapy in critically ill patients.

Journal ArticleDOI
01 May 2009-Chest
TL;DR: It is shown that EMST is a viable treatment modality for a population of participants with PD at risk of aspiration and significant decreases in the P/A scores were found posttraining.

Journal ArticleDOI
01 Dec 2009-Chest
TL;DR: No significant effect on BMD was detected for ICS therapy compared with placebo in the TORCH study, and osteoporosis is highly prevalent in patients with COPD, irrespective of gender.

Journal ArticleDOI
01 May 2009-Chest
TL;DR: The long-term administration of prophylactic nCPAP following cardiac surgery improved arterial oxygenation, reduced the incidence of pulmonary complications including pneumonia and reintubation rate, and reduced readmission rate to the ICU or intermediate care unit (IMCU).

Journal ArticleDOI
01 Nov 2009-Chest
TL;DR: This review discusses evolving conceptual mechanisms for the pathogenesis of pulmonary fibrosis relevant to idiopathic pulmonary fibrot, including the importance of the integrity of the alveolar-capillary barrier basement membrane to conserving the architecture of the injured lung.

Journal ArticleDOI
01 Mar 2009-Chest
TL;DR: The present study provides additional evidence that HCAP should be distinguished from CAP, and suggests that the therapeutic strategy for HCAP in the moderate class holds the key to improving mortality.

Journal ArticleDOI
01 Mar 2009-Chest
TL;DR: A systematic review of the effectiveness of CME for the Agency for Health Care Research and Quality found multiple media, multiple techniques of instruction, and multiple exposures to content are suggested to meet instructional objectives intended to improve clinical outcomes.